Structure of the cell Flashcards

1
Q

what is a eukaryote cell

A

cell that contains membrane bound organelles

- organelles are suspended in cytosol

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2
Q

what is evidence of cellular arrangement

A

light microscope x1500 allows cells to be seen clearly

- electron microscope x50000 can see the ultrastructure of cells - confirms proposed arrangement

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3
Q

What is the function of the cell membrane

A
  • separates the cytoplasm from the outside environment
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4
Q

structure of cell membrane

A

fluid mosaic model

  • phosphate head attached to a fatty acid chain
  • bilayer - tails point inwards
  • cholesterol molecules
  • lots of integral & peripheral proteins
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5
Q

what is the function of cholesterol in the CSM

A
  • help regulate fluidity and stiffens it
  • prevents small water soluble molecules from passing through
  • provides a suitable molecular environment for some transmembrane proteins
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6
Q

what is the function of integral & peripheral proteins in the CSM

A

integral-allow different substances in and out of cells

peripheral- can act as receptors

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7
Q

what is the structure of the nucleus

A

large double membrane-bound organelles that contains chromatin and the nucleolus
- nuclear envelope has pores and is selectively permeable between the nucleus and the cytoplasm

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8
Q

what does the nucleolus contain

A

DNA, RNA and proteins which regulate the cell cycle

- site for rRNA synthesis

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9
Q

what is the function of mitochondria?

A

generate chemical energy (ATP) necessary for biochemical reactions with aerobic stages respiration

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10
Q

what do number of mitochondria indicate?

A

level of metabolism

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11
Q

which cells have many mitochondria and why?

A

hepatocytes - active role in digestion
sperm cell - need ATP for motility
slow twitch skeletal muscle- high aerobic activity

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12
Q

structure of endoplasmic reticulum

A

3D network of cavities, some sac like and some tubular, bounded by membranes
- two types RER AND SER

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13
Q

structure and function of RER

A
  • surface studded by ribosomes which are essential for protein synthesis
  • packages and folds primary and secondary proteins into tertiary ones and transports in vesicles to golgi
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14
Q

which cells contain lots of RER

A

pancreatic epithelial - synthesis proteins to release into the lumen
plasma cells - to produce antibodies
nerve cell bodies - to produce proteins that are used internally and transported along the axon along microtubules

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15
Q

structure and function of SER

A

no ribosome on the surface
single tubular sacs
involved in lipid, glycogen and steroid synthesis and the detoxification of noxious substances

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16
Q

where is lots of SER found?

A

liver cells - lipid synth and detoxification of drugs by xenobiotic degradation

17
Q

structure of Golgi apparatus

A
  • stacks of parallel flattened membrane pockets (cisternae)
18
Q

function of golgi

A

modifies tertiary into quaternary or lipo/glycoproteins

  • dehydrates enzyme secretions
  • produce lysosomes
19
Q

lysosomes structure and functions

A

membrane bound organelles that contain hydrolytic enzymes

- decompose substances taken into the cell and destroy worn out organelles and foreign proteins

20
Q

what is glycogen

A

polymer of alpha glucose that is highly branched and absorbed from the digestive system and circulates in the blood
- can be made by most cells to allow ATP synth to take place

21
Q

why are lipid droplets found in some cells

A

store for triglycerides in the cytoplasm

22
Q

what is the structure of fat cells and why

A

nucleus pushed to the side
lack of organelles
capillaries in connective tissue between the cells
- this is because it is specialised for triglyceride storage

23
Q

what stain turns lipids black in an electron micrograph?

24
Q

what is the cytoskeleton

A

dynamic, 3D web like structure filling the cytoplasm that acts a framework to maintain the shape and polarity of the cell

25
what are the components of the cytoskeleton
microfilaments intermediate filaments microtubules
26
what are microfilaments
-strands of actin (contractile) so provide a dynamic framework
27
where are microfilaments important
microvilli - act as a core through the projection to increases SA, allow motility and anchor is to the actin cortex of the cell
28
what are intermediate filaments for?
purely structural and form assemblies inside the cell | there are 5 classes (e.g. neurofilaments)
29
what are microtubules
largest component of cytoskeleton and made of subunits that can assemble/disassemble to provide for changes in cell shape and position of organelles
30
what is the structure of centrioles
come in pairs | bundle of 9 tubules in star formation - one is vertical and one is flat
31
what is the function of centrioles
maintaining cell shape in non dividing cells and tracts for transporting vesicle and organelles to move from place to place - responsible for polymerising microtubules - in a dividing cell centrioles replicate, separate and move to opposite sides of the cell to pull out the mitotic spindle and cause separation of the cell
32
erythrocytes shape and reasoning
disc shaped cells lack nucleus and organelles can deform when passing through narrow channels and shape allows a lot of Hb
33
nerve cell structure and reasoning
long axon as there is need to communicate to the periphery
34
epithelial cell structure and reasoning
columnar cells and crushed together with high cell to cell contact - act as a barrier
35
skeletal muscle cell structure and reasoning
long and thin multinucleated allow contraction to take place with sliding filament theory