study guide Flashcards

(60 cards)

1
Q

what are the functions of the urinary system

A

regulating blood volume

stabilizing pH

eliminating organic wastes

secrete the hormones erythropoietin, calcitrol, and the enzyme renin

activation of vitamin D

regulation of water and electrolyte balances (Na, K, Cl, etc)

regulation of acid-base balance (pH) by controlling loss of hydrogen ions and bicarbonate ions in urine

regulation of (blood) arterial pressure

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2
Q

how is the kidney involved with normal bone ossifaction and development?

A

kidneys produce calcitriol

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3
Q

through which organ urine is eliminated

A

urethra

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4
Q

give the correct order in which urine passes, through the following structures

A

collecting duct
renal pyramids
renal pelvis
ureter
urinary bladder
urethra

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5
Q

what is the prominent indentation on the medial surface of the kidney

A

hilum

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6
Q

which is the cavity of the kidney that receives urine from the calyces

A

renal pelvis

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7
Q

through which blood vessel, blood leaves the glomerulus

A

efferent arteriole

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8
Q

what is the proper order for the structures of the renal corpuscle through which a substance passes during filtration?

A

capillary endothelium

dense layer

filtration slits

capsular space

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9
Q

what are renal columns

A

bundles of tissue that extend between pyramids from the cortex

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10
Q

in which part of the nephron the macula densa is found?

A

the distal convoluted tubule

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11
Q

name the hormones produced by the kidneys

A

erythropoietin

calcitriol

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12
Q

name the enzyme produced by the kidneys

A

renin

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13
Q

what is the role of kidneys in the activation of vitamin D

A

25-hydrocholecalciferol is hydroxylated to 1,25-dihydroxycholecalciferol

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14
Q

what is the primary fucntion of the proximal convoluted tubule

A

absorption of ions, organic molecules, vitamins, water

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15
Q

the following is a list of the blood vessels that carry blood tot he kidney. In what order does blood pass through these vessels

A

renal artery

interlobar artery

arcuate artery

cortical radiate artery

afferent arteriole

glomerulus

efferent arteriole

peritubular capillary

renal vein

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16
Q

what represents the amount of filtrate produced by the kidneys in one minute

A

glomerular filtration rate

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17
Q

by which method kidneys maintain the acid-base equilibrium of the body fluid

A

by reabsorption of bicarbonate ions and excretion of hydrogen ions

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18
Q

which hormone is responsible for making the distal and collecting tubule of the nephron to be permeable to water

A

anti diuretic hormone

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19
Q

if ADH is absent what type of urine will be produced

A

hypotonic urine

diabetes insipidus is a rare disease caused by deficiency of Antidiuretic Hormone (ADH)

deficiency of antidiuretic hormone (ADH) causes polyuria (excessive passage of urine)

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20
Q

where does potassium secretion take place in kidneys

A

distal tubule

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21
Q

which element is retained by the action of aldosterone on kidney tubules

A

sodium

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22
Q

in kidneys urine formation starts with filtration. It is possible because

A

efferent arteriole is narrower than afferent arteriole

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23
Q

in which segment of the nephron is sodium transported out of the nephron

A

proximal convoluted tubule

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24
Q

what is the composition of blood in the renal artery and renal vein

A

renal artery contains more oxygen, less carbon dioxide, and more urea than renal vein

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25
in which part of the renal tubule most of the water reabsorbed
proximal colvulted tubule
26
which part of the nephron is permeable to water due to ADH
last 1/3 of the distal convoluted tubule and collecting duct
27
when the pH of the blood is low, which substance is likely to be excreted in larger quantities in the urine
hydrogen ions
28
which process in the kidney regualtes the H+ concentration of the blood
tubular secretion
29
what is Angiotensinogen
a protein produced in the liver and present in the blood plasma
30
which process produces urea
deamination excess amino acid are broken down in the liver to produce urea
31
which cells produce renin
juxtaglomerular cells in the afferent and efferent arterioles
32
where is urea produced
liver
33
what is the correct path of the flow of glomerular filtrate in the kidneys
glomerulus proximal tubule henle's loop distal tubule collecting duct renal papilla renal pelvis
34
what is renin, give its function
renin is an enzyme produced by kidneys function: converts the plasma protein angiotensinogen formed in the liver to angiotensin 1 it is produced when the blood pressure and glomerular filtrate volume decrease
35
what is the role of angiotensin 2 maintaining blood pressure
angiotensin 2 constricts the walls of arterioles closing down capillary beds stimulates the proximal tubules in the kidney to reabsorb sodium ions stimulates the adrenal cortex to release aldosterone stimulates thirst triggers release of antidiuretic hormone (ADH) stimulates reabsorption of water in distal portion of DCT and collecting system mobilizing the venous reserve increasing cardiac output stimulating peripheral vasoconstriction elevating arterial pressures throughout body
36
an obstruction of a ureter by a kidney stone limits the flow of urine between which 2 points
renal pelvis urinary bladder
37
what effect does eating a high-protein diet have on the composition of urine
increased urea
38
damage to which part of the nephron interferes with hormonal control of blood pressure
juxtaglomerular apparatus
39
how are cortical and juxtamedullary nephrons structurally different
juxtamedullary nephrons have longer nephron loops
40
what is the composition of the filtrate in the capsular space
similar to plasma, only no proteins
41
which mechanism the kidney uses to raise systemic blood pressure
increase secretion of renin by the juxtaglomerular complex
42
a patient excretes a large volume of very dilute urine on a continuing basis. which of the following causes this condition
absence of ADH
43
what is the area of the urinary bladder bounded by the openings of the 2 ureters and the urethra
trigone
44
where do the renal veins drain blood into
inferior vena cava
45
the cells of the macula densa and the juxtaglomerular cells from the
juxtaglomerular complex
46
what is the structural and functional unit of kidneys
nephron
47
what is the function of vasa recta
to create the osmotic gradient in the medulla of the kideny to produce hypertonic urine involves the reabsorption in to the medullary interstitial fluid of Na+, Cl-, urea, and water acculmation of excess of these substances in the medulla is prevented by their removal in to the blood stream by vasa recta
48
what are the 3 processes involved in urine formation
glomerular filtration tubular reabsorption tubular secretion
49
what are the advantages of tubular reabsorption
very important to conserve water, ions, and important nutrients in out body also helps to control blood pH
50
main purpose of tubular secretion
removes wastes and regulate the H+ concentration of the blood
51
how is sodium reabsorbed in the proximal part of the tubule
by contransport with bicarbonate, glucose, amino acids, and phosphate water follows the Na+
52
what is the role of aldosterone in maintaining blood pressure
stimulates tubular reabsorption of sodium water follows sodium ions out of the nephron in to the peritubular capillaries thus restoring the blood volume and blood pressure increases the strength of the heartbeat stimulates the pituitary to release the ADH or vasopressin all these action lead to an increase in blood pressure
53
what are the componets of the juxtaglomerular appartus
consists of macula densa cells in the initial portion of the distal tubule and juxaglomerular cells in the walls of the afferent and efferent arterioles and the lacis or extraglomerular cells (unknown function)
54
function of macula densa
a fall in tubular Na+ and Cl- is detected by the macula densa and causes an increased renin secretion
55
what is the function of juxtaglomerular cells
of the afferent and efferent arterioles secrete renin and stores renin
56
what are the methods by which acid-base balance is maintained in our body
kidneys excrete H+ ions and conserve base (HCO3) buffer systems bind free H+ lungs eliminate CO2
57
what are the common kidney diseases
chronic kidney diseases (CKD) kidney failure kidney stones diabetes insipidus
58
what are the layers of the wall is the ureters
inner mucosa middle muscular layer outer connective tissue layer
59
which enzyme activate angiotensin 1 in to activated angiotensin 2 (active form)
enzyme produced by the endothelial lining of the blood capillaries of the alveoli
60
what are the 2 factors that inhibit the secretion of ADH
increase in blood volume increase in blood pressure inhibit the secretion of ADH