Study guide test 3 Flashcards

1
Q

Caudal regression syndrome is commonly found in patients with what?

A

diabetes

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2
Q

What term defines the appearance of overlapping skull bones that indicates fetal death?

A

Spalding’s sign

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3
Q

What would fetal hydrops appear like under US and what are the sonographic findings?

A

scalp edema

pleural effusion

pericardial effusion

ascites

polyhydramnios

thickened placenta

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4
Q

If hydrops is caused by tachycardia, what would the fetal heart rate be?

A

200-240bpm

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5
Q

If a pregnant woman has a baby, and she is a patient of size, what is there an increased incidence of?

A

increased incidence of neural tube defects

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6
Q

What is caudal regression syndrome?

A

lack of development of the caudal spine and cord

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7
Q

What skeletal and central nervous system anomalies are found in infants of diabetic mothers?

A

caudal regression syndrome

neural tube defects excluding anencephaly

anencephaly with or without herniation of neural elements

microcephaly

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8
Q

When is it considered premature labor?

A

onset of labor before 37wks gest

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9
Q

Monochorionic twins, what anomaly is it when one twin develops without a heart or upper body?

A

acardiac anomaly

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10
Q

Twin to twin transfusion syndrome:

A

exists when there is an arteriovenous shunt within the placenta

arterial blood of one twin is pumped into the venous system of the other

one twin has less blood flow(develops oligo)

one twin has too much blood flow(develops poly)

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11
Q

What is poly-oli sequence?

A

diamniotic pregnancy: one sac has poly, the other has severe oligo and a smaller twin

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12
Q

What is another name for poly-oli sequence?

A

stuck twin

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13
Q

Development of conjoined twins occurs how many days after conception?

A

if division occurs after 13 days

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14
Q

Stuck twin syndrome is usually observed in what weeks?

A

usually manifests between 16-26wks gest

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15
Q

Diamniotic and dichorionic twin preg demonstrates what sonographic findings?

A

2 amnions and 2 chorions

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16
Q

What is demonstrated when one fertilized egg division occurs 4-8 days after fertilization?

A

one chorion and two amniotic sacs (monochorionic diamniotic)

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17
Q

What are the predictors of discordant in the growth of twins?

A

difference in estimated fetal weight of more than 20%

difference in BPD of 6mm

difference in AC of 20mm

difference in femur length of 5mm

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18
Q

Most frequent cause of nonimmune hydrops:

A

cardiovascular lesions

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19
Q

What are the advantages of chorionic villi samplings?

A

it is performed early in preg (10-14wks)

results are available within 1wk

earlier results allow more options for parents

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20
Q

Cordocentesis is more commonly used for what procedure?

A

guidance for transfusions to treat fetal isoimmunization

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21
Q

What is amniocentesis used for?

A

first used: to relieve polyhydramnios, Rh isoimmunization, document fetal lung maturity

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22
Q

Why do we perform amniocentesis?

A

offered to patients who are at risk for chromosomal abnormalities or biochemical disorders

23
Q

Twins that arise from two separately fertilized ova are what type of twins?

24
Q

Sonographic findings that suggest chromosomal anomalies include:

A

Tri 21: nuchal thickness, heart defects, duodenal atresia, shortened femurs, mild pyelectasis, mild ventriculomegaly, echogenic bowel

Tri 18: heart defects, choroid plexus cysts, clenched hands, micrognathia, talipes, renal anomalies, cleft lip and palate, omphalocele, CDH, cerebellar hypoplasia

Tri 13: holoprosencephaly, heart defects, cleft lip and palate, omphalocele, polydactyly, talipes, echogenic chordae tendineae, renal anomalies, meningomylocele, micrognathia

triploidy: hydatidiform placental degeneration, heart defects, renal anomalies, omphalocele, cranial defects, facial defects

Turner’s syndrome: cystic hygroma, heart defects, hydrops, renal anomalies

25
AFP is found in what fetal structures?
major protein in fetal serum, produced by yolk sac in early gest and later by the fetal liver found in fetal spine, gastrointestinal tract, liver, and kidneys
26
High levels of AFP indicate what?
neural tube defects-anencephaly and open spina bifida
27
What markers does the quad screen evaluate?
AFP, human chorionic gonadotropin (hCG), and unconjugated estriol
28
What is an abnormality of the number of chromosomes called?
aneuploidy
29
What is an early noninvasive means of assessing the risk of aneuploidy?
PAPP-A, and beta hCG levels-blood test
30
Following sono findings of thickening nuchal, shortened femurs, cardiac anomalies, and hydro, what do we look for?
Trisomy 21
31
Sonographic findings of cranial anomalies, choroid plexus cyst, facial abnormalities, and rocker bottom feet?
Trisomy 18
32
Holoprosencephaly and proboscis are found in what type of fetus?
Trisomy 13
33
Secondary to pregnancy include hypertension, coma, seizure in 2nd and 3rd tri represent what?
eclampsia
34
Large cystic hygroma, hydrops, coartation (arch/ascending, split, b/c of trauma) of the aorta may be seen in a fetus with what condition?
Turner's syndrome
35
Pregnancy associated with PAPP-A levels, what do they do?
increase throughout preg decrease in preg affected by aneuploidy
36
AFP produced early in gest by what structure?
yolk sac
37
Common reason for an elevated MSAFP is what?
twin pregnancy
38
What is the most common aneuploidy condition?
Down's syndrome (trisomy 21)
39
An optimal collection site in an amniocentesis is what?
away from the: fetus, central portion of the placenta, and umbilical cord near the maternal midline to avoid the maternal uterine vessels
40
MSAFP levels increase with advancing gest age and peak at how many wks gest?
15-18wks gest
41
Free beta hCG can be assessed in maternal serum in the 1rst tri to evaluate an increased risk of what condition?
Down syndrome
42
After amnio, sonographer should document what?
cardiac activity
43
Continuous monitoring with US during amnio is invaluable in cases of what?
oligohydramnios, anterior placental position, and premature rupture of membranes
44
Fetal death that occurs after the fetus has reached a certain growth that is too large to reabsorb into the uterus is called what?
fetal papyraceus
45
Low AFP levels have been found in this condition (most common)?
trisomy 21, 18, and 13
46
What is the picture of the chromosomes called?
karyotyping
47
Abnormal NT increases fetal risk for what?
tri 13, 18, 21 triploidy Turner's syndrome
48
What is associated with Turner's syndrome?
cystic hygroma heart defects hydrops renal anomalies
49
Which is included in 1rst tri maternal serum screening?
PAPP-A free beta hCG
50
Conjoined twins: 5 most common types
thoracopagus-joined at thorax omphalopagus-joined at the anterior wall craniopagus-joined at the cranium (syncephalus-conjoined twins with one head) pygopagus-joined at the ischial region ischiopagus-attached at the buttocks
51
Autosomal dominant
dominant disorder, condition caused by a single defective gene usually inherited by 1 parent who is affected may arise as a new mutation
52
Autosomal recessive
recessive disorder, caused by a pair of defective genes, one inherited from each parent 25% chance of having a fetus with a disorder
53
Mosaic patterns
mosaicism:occurrence of a gene mutation or chromosomal abnormality in a portion of an individual's cells