Substance of Abuse Flashcards

(42 cards)

1
Q

Other names for Ethanol

A

Grain alcohol
Spiritus vini rectificatus
Neutral spirit

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2
Q

Most widely abused recreational substance

A

Ethanol

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3
Q

Responsible for major medical and socioeconomic problems

A

Ethanol

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4
Q

Alcohol content of Beer

A

4-5%

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5
Q

Alcohol content of Wine

A

10-14%

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6
Q

Alcohol content of Distilled spirits

A

30-50%

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7
Q

Metabolites of Alcohol

A

Acetaldehyde, Acetic Acid

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8
Q

S/S of Alcohol Poisoning

A

CNS depression, Acid-base Imbalance,
Metabolic Acidosis, Impaired Thermal Regulation
Hypoglycemia, Coma, Tachycardia

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9
Q

Treatment of Acute Alcohol Toxicity

A

Supportive Care
Fluids and Electrolytes
Vit B1 (Thiamine)

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10
Q

Treatment of Chronic Alcohol Poisoning

A

Disulfiram - Aldehyde dehydrogenase Inh
Naltrexone, Acamprosate - Reduce cravings and Inc. Abstinence rate
Behavioral Therapy

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11
Q

Active Ingredient of Tobacco

A

Nicotine

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12
Q

Lethal dose of Nicotine

A

Adult: 40-60mg
Child: 1.5 - 2 mg/kg

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13
Q

Treatment of Nicotine Toxicity

A

Activated Charcoal
Gastric Lavage
Mecamylamine (Inversine®)

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14
Q

From Papaver Somniferum (opium poppy)

A

Opioids

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14
Q

Natural Opioids

A

Opium, Morphine

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15
Q

Semi-synthetic Opioid

A

Heroin (Diacetylmrphine)
Codeine (Methylmorphine)

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16
Q

Synthetic Opioids

A

Methadone & Meperidine (Pethidine)

17
Q

Opioid Toxicity Manifestations

A

Coma (LOC)
Miosis (pinpoint pupil)
Respiratory depression

18
Q

Meperidine may cause

19
Q

Treatment for Opioids Toxicity

A

Naloxone
(pure Antagonist)
Naltrexone
Nalorphine
Nalmefen

20
Q

Hallucinogens

20
Q

Hallucinogens

A

Lysergic Acid Diethylamide (LSD)
Marijuana
Phencyclidine
Mescaline
Lysergic Acid Amide (LSA)

21
Q

Marijuana is derived from?

A

Cannabis sativa/sativum

22
Q

Other names for Marijuana

A

Mary Jane, Hashish, Indian Hemp, Weeds

23
Most commonly used Illegal Drug
Marijuana
24
Active constituent of Marijuana
△-9-tetrahydrocannabinol (THC) Cannabidiol
25
Angel Dust
Phencyclidine
26
Dissociative anesthetic
Phencyclidine
27
S/S of Phencyclidine Poisoning
Low: Bloodshot eyes, Loss of balance Med: Anesthesia, HPN High: Convulsion
28
Tx of Phencyclidine poisoning
Benzodiazepine, Diazepam (for seizure) Nitroprusside (for HPN)
29
Mescaline is derived from
Peyote cactus (Lophophora williamsii)
30
Mescaline Toxicity S/S
Sympathomimetic Toxidrome
31
TF: LSD is an Ergot derivative
True
32
Most potent hallucinogen
LSD
33
LSA is derived from
Morning glory family (Ipomoea indica)
34
Shabu
Methamphetamine
35
Ecstasy
3, 4-methylenedioxy-N-methamphetamine, or MDMA
36
S/S of Amphetamine poisoning
Seizures Psychosis/Agitation Hypertensive crisis Arrhythmias
37
Treatment for Amphetamine Poisoning
Seizures: Diazepam, Phenytoin Psychosis/Agitation: Chlorpromazine, haloperidol, Diazepam Hypertensive crisis: B-blockers, a-blockers Arrhythmias: Propanolo, Lidocaine
38
Cocaine is derived from
Erythroxylon coca
39
Cocaine
Crack, Freebase
40
Treatment of Cocaine Toxicity
Seizures: Benzodiazepine Psychosis: Neuroleptics HPN: Labetalol