SUD Lecture Flashcards
1
Q
All addicting substances and behaviors
directly or indirectly affect the ? pathways,
A
dopamine
2
Q
As ? is the
primary neurotransmitter associated with the reinforcing effect of the substance.
A
dopamine
3
Q
DSM criteria for alcohol use disorder (at least ? of the following occurring in a ?-month
period)
A
2
12
4
Q
Screening of substance use disorders
Diagnostic Tools - ?
A
None
5
Q
Screening of substance use disorders
3 Screening Tools
A
CAGE
AUDIT – C
AUDIT
6
Q
CAGE: ? question screening
A
4
7
Q
AUDIT – C: ? question screening
A
3
8
Q
AUDIT: ? question screening
A
10
9
Q
Have you ever felt the
need to cut down on
your drinking?
CAGE
A
C
10
Q
Have people annoyed you by
criticizing your drinking?
CAGE
A
A
11
Q
Have you ever
felt guilty about drinking?
CAGE
A
G
12
Q
Have you ever felt you
needed a drink first thing
in the morning to steady
your nerves or to get rid
of a hangover (eye-
opener
CAGE
A
E
13
Q
What do each C mean
CAGE
A
Cut
14
Q
What do A mean
CAKE
A
Annoyed
15
Q
What does G mean
CAGE
A
Guilt
16
Q
What does E mean
CAGE
A
Eye opener
17
Q
AUDIT-C
A score greater than ? for men is at risk
A
4
18
Q
AUDIT-C
A score greater than ? for women is at risk
A
2
19
Q
Pharmacokinetics of Alcohol
Primarily metabolized in the ?
leading to ?
A
Liver
Cirrhosis
20
Q
Pharmacokinetics of Alcohol
?% is excreted in sweat, breath and urine
A
10
21
Q
Pharmacokinetics of Alcohol
? is the chemical name for alcohol
A
Ethanol
22
Q
10% is excreted in 3?
A
sweat, breath and urine
23
Q
Responsible for “rewarding” effect
A
Dopamine
24
Q
The inability to withhold a prepotent response or suppress an inappropriate or unwanted behavior which is casue d by alcohol ingestion
A
Disinhibition
25
Alcohol effects
S
D
R
D
S
N
Sedation,
Disinhibition,
Relaxation,
Decrease coordination
Slurred speech
Nausea
26
Alcohol Overdose
R
C
Respiratory depression
Cardiac arrest
27
Alcohol Withdrawal
T
S
E
D
Tremors,
seizures,
elevated temperature pulse blood pressure
Delirium tremens
28
Alcohol
Prolonged use : Effects or systems of the body. Can lead to other ? 2
dependencies, and malnutrition
29
Causes agitation, restlessness, anxiety, and sweating.
Alcohol Withdrawal vs. Alcohol Effects/overdose
Alcohol Withdrawal
30
Can lead to slowed brain function, cognitive impairment, coma.
Alcohol Withdrawal vs. Alcohol Effects/overdose
Alcohol Effects/overdose
31
VS:
elevated HR,
elevated temp,
normal or slightly elevated systolic BP
Mild, Moderate, Severe AWS
Mild
32
Ranges for normal temp in F
97 to 99
33
Ranges for normal temp in C
36.1 to 37.2
34
With alcohol withdrawal syndrome is ? of BP is priorty
Systolic
35
VS:
Heart rate 100-120 BPM elevated systolic BP
Elevated temperature
Mild, Moderate, Severe AWS
Moderate
36
VS
Heart rate 120 - 140 BPM; Elevated Systolic and Diastolic BP
Elevated temperature
Mild, Moderate, Severe AWS
Severe
37
Mild AWS
Diaphoresis :?
Slight
38
Moderate AWS
Diaphoresis :?
Obvious
39
Severe AWS
Diaphoresis :?
Marked
40
No confusion no hallucinations
Mild, Moderate, Severe AWS
Mild
41
-Intermittent confusion; transient visual
-Auditory hallucinations and
illusions (mostly at night)
Mild, Moderate, Severe AWS
Moderate
42
-Marked disorientation
-confusion
-disturbing visual and auditory
hallucinations
Mild, Moderate, Severe AWS
Severe
43
-Misidentification of objects delusions related to the hallucinations
Mild, Moderate, Severe AWS
Severe
44
Delirium tremens
Mild, Moderate, Severe AWS
Severe
45
disturbances and consciousness agitation
Mild, Moderate, Severe AWS
Severe
46
-Extreme restlessness and panic state unable to sleep
-Gross uncontrollable tremors
-Convulsions
Mild, Moderate, Severe AWS
Severe
47
mild anxiety and restlessness
restless sleep
Mild, Moderate, Severe AWS
Mild
48
hand tremors; shakes
Mild, Moderate, Severe AWS
Mild
49
no convulsions
Mild, Moderate, Severe AWS
Mild
50
Convulsions
Mild, Moderate, Severe AWS
Severe
51
Painful anxiety and motor restlessness
Mild, Moderate, Severe AWS
Moderate
52
insomnia and nightmares
Mild, Moderate, Severe AWS
Moderate
53
Visible tremulousness
Mild, Moderate, Severe AWS
Moderate
54
Rare convulsions
Mild, Moderate, Severe AWS
Severe
55
-Gross uncontrollable tremors
Mild, Moderate, Severe AWS
Severe
56
GI: impaired appetite, nausea
Mild, Moderate, Severe AWS
Mild
57
GI: anorexia, nausea and vomiting
Mild, Moderate, Severe AWS
Moderate
58
GI: rejecting all fluid and food
Mild, Moderate, Severe AWS
Severe
59
The following is what?
Determine if patient is at risk of withdrawal
Main Priority due to safety
60
Clinical Institute Withdrawal Assessment for
Alcohol Scale, Revised (CIWA-Ar)
V
N
V
T
A
H
P
C
Vital sign changes
Nausea
Vomiting
Tremors
Agitation
Headache
Perspiration
Change in mental status
61
Perspiration
the process of sweating
62
Diaphoresis
Sweating
63
What medication suppresses the CNS with give a sedative affect similar to alcohol?
Benzodiazepines (BENZOS)
64
Short acting Benzos for AWS
Lorazepam (Ativan)
65
Long-acting Benzos for AWS
Chlordiazepoxide (Librium)
Diazepam (Valium)
66
Benzos are the other drugs for ?
alcohol withdrawal not abuse
67
First line treatment of alcoholism
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
a. Naltrexone hydrochloride (ReVia)
68
An opioid receptor antagonist initially used to treat narcotic
dependence and is approved for treatment of alcohol dependence.
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
a. Naltrexone hydrochloride (ReVia)
69
increases abstinence and reduces alcohol cravens
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
a. Naltrexone hydrochloride (ReVia)
70
monthly injection
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
a. Naltrexone hydrochloride (ReVia)
71
won't stop the individual from drinking but extends periods of sobriety
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
a. Naltrexone hydrochloride (ReVia)
72
Use when abstinence started but not while the person is still drinking.
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
b. Acamprosate calcium
73
Can be used in conjunction with other medications to support but the outcome of recovery
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
b. Acamprosate calcium
74
an aversive medication, the patient is aware that they will get sick if they drink alcohol while taking this this medication.
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
c. Disulfiram (Antabuse)
75
This medication is not recommended unless the
patient is in full awareness of the side effects.
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
c. Disulfiram (Antabuse)
76
Inhibits the breakdown of acetaldehyde because acetaldehyde is toxic if a
person drinks?
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
c. Disulfiram (Antabuse)
77
they will become ill with the following symptoms
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
c. Disulfiram (Antabuse)
78
This medication is most effective in patients with
moderate motivation for long term recovery and sobriety
a. Naltrexone hydrochloride (ReVia)
b. Acamprosate calcium
c. Disulfiram (Antabuse)
c. Disulfiram (Antabuse)
79
Disulfiram symptoms
D
f
H
N
V
P
T
T
W
D
M
S
D
A
Diaphoresis
flushing of the neck and face
Hypotension
Nausea
Vomiting
Palpitations
Tachycardia
Tremor
Weakness
Dyspnea
MI
Seizures,
Death cardiac failure Arrhythmias
80
With Disulfiram pt should avoid
W
N
M
B
A
L
Wine
None alcoholic beer
Malt vinegar
Baked goods
Aftershaves
Lotions
81
Alcohol toxic to the brain – causes ? to frontal cortex and ? brain syndrome
atrophy
chronic
82
Poor dietary intake can lead to deficiencies or insufficiencies of 3
folic acid, thiamine and other B vitamins.
83
Degenerative brain disorder caused by thiamine deficiency
Wernicke vs Korsakoff
Wernicke
84
Involves the heart, vascular and nervous system. Inability to acquire new information and retrieve memories
Wernicke vs Korsakoff
Korsakoff
85
Wernicke
C
H
V
U
C
Confusion
hypotension
visual impairment
unsteady gait
Coma
86
Korsakoff
A
D
A
V
C
Attention deficit
Disorientation
Amnesia
Visual impairment
Confabulation
87
A neuropsychiatric disorder wherein a patient generates a false memory without the intention of deceit?
Confabulation
88
Wernicke encephalopathy -degenerative brain disorder caused by ? deficiency
Thiamine
89
Chronic AUD (Alcohol Use Disorder)
D
? after last intake of alcohol
Life threatening
A
S
A
A
D
Delirium tremens
48-72
A/V Hallucinations
Shaking
Altered Mental Status (Confusion)
Aspiration
Death
90
Chronic AUD (Alcohol Use Disorder)
? after last intake of alcohol
48-72 after last intake of alcohol
