Sunday Flashcards

(30 cards)

1
Q

Emphysema

A

Histological description of alveolar wall destruction with airway collapse and air trapping

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2
Q

Chest X-ray features of COPD

A

Hyperinflation over 10 posterior ribs, flat diaphragm
Pulmonary hypertension: prominent pulmonary arteries
Bullae

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3
Q

Management of COPD

A

MDT
Smoking cessation
Pulmonary Rehabilitation (tailored exercise program, psychosocial support)
Comorbidites and vaccines (pneumococcal and flu)
Med: SABA, SAMA, inhaled corticosteroids
Home emergency pack

Ltot if PaO2

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4
Q

Chronic bronchitis definition

A

Cough productive of sputum for over 3 months on most days for over 2 consecutive years

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5
Q

Management of Fibrotic lung disease

A

Find underlying cause

Stop smoking
Pulmonary rehabilitation
LTOT
sympathetic treatment: antitussives, heart failure

Surgery only if Idiopathic Lung Fibrosis

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6
Q

Imaging features of bronchiectasis

A

X-ray: tramlines and ring shadows(bunch of grapes)

High resolution CT: Signet Ring Sign (thickened dilated bronchi and smaller adjacent vascular bundle)
Pools of mucus in saccule dilatation a

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7
Q

Complications of Bronchiectasis

A
Cachexia
Pulmonary hypertension
Massive haemoptysis
Type 2 respiratory failure
Amyloidosis
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8
Q

Management of Bronchiectasis

A

Conservative:
MDT and physio

Medical:
Antibiotics for exacerbations
Bronchodilators
Treat underlying cause
Vaccination (flu and pneumococcus)

Surgical: may be indicated in severe localised disease or obstruction

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9
Q

Ghon focus

A

Primary TB, organism multiplies at pleural surface

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10
Q

Ranke Complex

A

Fibrosis of Ghon complex giving calcified nodule

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11
Q

Investigations in TB

A

Active TB:
Chest X-ray and cultures, also microscopy for acid fast bacilli

Latent:
Mantoux test,
Elispot (patient lymphocytes incubated with specific TB antigens to see if IFNgamma production)
PCR

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12
Q

Extra pulmonary features of Cystic Fibrosis

A

Pancreatic: Diabetes, malabsorption
Gut: Distal Intestinal Obstruction Syndrome
Reproductive: infertility
Liver: gallstones and cirrhosis

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13
Q

Management of Cystic Fibrosis

A

Physiotherapy: postural drainage
Antibiotics: prophylactic and for acute exacerbations
Mucolytics
Segregate from other CF patients (Burkholderia risk)
Vaccination

Pancreatic supplements, ADEK, insulin

Fertility and genetic counselling

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14
Q

Causes of hyperthyroidism

A

Graves (increased uptake)

Toxic multinodular goitre= plummers
De quervains

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15
Q

Common causes hypothyroidism

A

Primary atrophic goitre (autoimmune)
Hashimotos
Simple colloid goitre (iodine deficiency)

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16
Q

Triple assessment for suspected thyroid lesion

A

Clinical examination
Ultrasound
FNAC

17
Q

Practicalities of thyroid surgery

A

Render euthyroid pre op with antithyroid drugs but stop 10 days before surgery (they increase vascularity)

Check for phaeo pre op if medullary carcinoma

Laryngoscopy pre and post op

18
Q

Causes of lump in anterior triangle

A

Lymph node
Goitre
Branchial cyst
Carotid body tumour (at carotid bifurcation, mostly benign)

19
Q

Causes lump in posterior triangle

A

Lymph node
Pharyngeal pouch
Cervical rib (overdevelopment of transverse process of c7)

20
Q

Causes of a cervical lymphadenopathy

A
LIST
Lymphoma or Leukaemia
Infection: EBV, TB, tonsillitis
Sarcoidosis
Tumours from elsewhere: breast, lung, ENT, gastro
21
Q

Complications of a parotidectomy

A

Immediate:
Facial nerve injury
Reactionary haemorrhage

Early:
Temporary facial weakness
Salivary fistula
Loss of pinna sensation (greater auricular nerve damage)

Late:
Frey’s syndrome= facial sweating whilst eating

22
Q

Risk factors for breast disease

A

BOOBYS
Bleeding in life (early menarche, late menopause)
Oestrogen: OCP, HRT
Other breast disease: previous cancer, DCIS
Breast feeding is protective
Young un > 35
Sister (family history)

23
Q

Classification of chronic venous disease (varicose)

A
CEAP
Clinical signs (>6 +symptomatic or asymptomatic)
Etiology
Anatomy
Pathophysiology
24
Q

Conservative measures for varicose veins

A

Lose weight and regular exercise
Avoid prolonged standing
Compression stockings
Skin care: emollients

25
Management of chronic limb ischaemia
``` Non surgical: Walk through pain Optimise risk factors Antiplatelets and statins Foot care ``` Interventional: Angioplasty with or without stenting Surgical: Endarterectomy Bypass grafting Amputation
26
What is a DatScan?
Injection of Ioflupane isotope, binds to dopamine rigid neurones and allows visualisation if substantia nigra Used in diagnosis of Parkinson's
27
Causes of cerebellar pathology
``` DATIES Demyelination Alcohol Tumours or Trauma Inherited eg Wilsons Epilepsy medications eg Phenytoin Stroke ```
28
Management of Multiple Sclerosis
MDT Acute: methylprednisolone Preventing relapse: disease modifying IFNbeta Glatirimir Preventing Relapse: Biologics Natalizumab (anti VLa4 antibodies) Alemtuzumab (Campath) Symptomatic: fatigue, depression, pain, spasticity, urgency
29
What is Myasthenia Gravis?
Neuromuscular disease causing fluctuating muscle weakness as a result of antibodies to Acetylcholine receptors on the post synaptic membrane
30
Management of Myasthenia Gravis
Acute: plasmapheresis or IVIg, monitor FVC and consider ventilation Chronic: Pyridostigmine (anticholinesterase inhibitor) Immunosuppression with steroids and Azathioprine Thymectomy