Supplements Flashcards

1
Q

What are supplements

A
  • supplements classed in legislation
    = complementary compound feedstuff
  • compound feed = mix of at least 2 feed materials for feeding to animals in oral form as either a complete feed or a complementary feed
  • Complementary feed = compound feed which has a high content of certain substances but is required to be fed with other feedstuffs to make a complete ration
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2
Q

legal requirements of supplements - specific regulations

A
  • Regulation 767/2009 on placing on the market and use of feed
  • Regulation 1831/2003 on additives for use in animal nutrition
    ~ additives= amino acids, flavour, pre/probiolitcs
    ~ if not registered cant use
  • Directive 2002/32/EC on undesirable substances in animal feed
    ~ toxins, metals, slamonella
  • Regulation 2017/1017 provides a catalogue of feed materials
  • Directive 2008/38/EC on intended uses of animal feedingstuffs for particular nutritional purposes
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3
Q

legal products of supplements - definicion of medicinal products

A
  • must abide to regs governing medical products
  • if it has an effect on animal = needs
  • presentation implies that they are medicinal (tablets, syringes)
    = any substance/combination of substances that may be used in, or administered to, animals with a view either to restoring, correcting or modifying physiological functions by exerting a pharmacological, immunological or metabolic action, or to making a medical diagnosis
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4
Q

examples words manufacturers not legally use

A
Cause 
Inflammation
Disease (mention)
Injuries
Support / Boost
Treat
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5
Q

NOPS

  • what is it
  • what certified companies do
  • how do nops occur
A

= naturally occuring prohibited substances
= voluntary scheme ran by the British Equestrian Trade Association
- if company NOPS certified = must put processes in place to reduce occurance of NOPS in feeds/sup
- NOPS are compounds that shown to have physiological effect on horse
~ result in positive drugs test
- either naturally present within ingreedinets or occur result of inadvertant cross contamination

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6
Q

NOPS

- main NOPS and sources

A
  • Caffeine – cacao, coffee, tea
  • Theobromine – cacao
  • Theophylline – tea
  • Morphine – opium poppy (risk buy herbs abroad), Papaver somniferum
  • Hyoscine – nightshade, Datura
  • Atropine – nightshade, - Atropa belladonna
  • Cannabinoids - Hemp fibre and plant material
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7
Q

What purposes are supplements produced

A
  • Support joints (biggest seller)
  • Calm excitable behaviour
  • Supply vitamins and minerals
  • Promote healthy skin and coat
  • Support hoof growth
  • Promote digestive health

BUT not alturnative for good feeding practices, need to feed balanced diet for individual needs

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8
Q

How are supplements fed and why increased usage

A
  • changes in feeding practices = increased use
  • fed small quantities = concentrated formulation
    ~ high concentration
  • need to understand supp func so fed correctly/safely
    ~ feeding vit/min supp full amount conc feed = excess
    ~ unbalance diet
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9
Q

Why increased use of supplements

A
  • Horses require less feed than previous due to undertaking less exercise = become overweight so need to feed less concentrates but still provide essential nutrients
  • cheaper
  • Balances diet
  • Increased availability
  • Increased product ranges and investments by companies
  • Targeted support
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10
Q

sourcing ingredients

A
  • vast ingredients
  • ingredients can be restricted
  • need to have full traceability
  • supplements for specific purposes should contain certain ingreedients
    ~ Research findings indicate they are effective
    ~ Traditional use has indicated they are effective
    ~ Anecdotal evidence indicates they are effective
  • lack of research = expensive and ethical concerns
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11
Q

supplements for joint support

A
  • most popular
  • reflects freq that equids are affected by osteoarthritis
    ~ most common cause of lameness in equids
  • strain on joints for performance activities (jumping = greatest)
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12
Q

suplements for joint support - why lack research

A
  • lab research using tissue/cell samples indicate some ingredients effective reducing joint degredation
  • limited studies using live equids
  • if include antinflamtorys = benefit = reduce pain and swelling
  • diff to measure lameness = influenced by many factors
    ~ stride lengths, joint and flexion now better measurements
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13
Q

joint supp - glucosamine

A
  • essential to skin, tendons, ligaments and articular cartilage
  • 2 forms
    ~ glucosamine hydrochloride (most use)
    ~ glucosamine sulphate
  • which form more effective still uncertain = more research needed
    ~ sulphate has slightly higher absorption rate (both low 2.5-6% oraly)
  • shown to work best when administered with chondroitin sulphate = protect articular cartilage
  • recomended 10g for 500kg horse = 0.02g/kg BW
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14
Q

joint supp - chondroitin

A
  • A component of articular cartilage usually supplemented as Chondroitin sulphate
    ~ Thought to inhibit cartilage breakdown although further research needed
  • Absorption of oral Chondroitin sulphate is higher than Glucosamine
    ~ Approximately 30-35%
  • Sources of Chondroitin are bovine/porcine/avian cartilage and shark fin
    ~ Shark fin is commonly used in equine supplements after BSE outbreak
  • Recommended amount unclear
    ~ Most supplements contain 2mg/kg BW/day
    ~ 500kg = 1000mg or 1g per day
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15
Q

joint supp - MSM

A

= methyl sulphonyl methane
- 2 roles
~ sulphur = provide strength to articular cartilage
~ acts as antioxidant = protects against cell damage
- few studies into msm and effectiveness
- most joint supp contain msm
- reccomende amount = 20mg/kg BW/day

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16
Q

joint supp - Hyaluronic acid

A
  • HA important component in joint fluid and articular cartilage = elasticity of joint
  • help reduce inflamation (swelling and pain)
  • can be injetced into joint capsule but risk infection
  • oral supp shown to be absorbed but amount reaching joint unknown
  • rec amount = 0.15mg/kg BW/day
17
Q

function of joint supplements

A

func ingredients = support tissue within joint, reduce swelling and pain
~ herbal ingredients shown to have effective anti-inflam properties (e.g. boswellia, devils claw (nops))
- some studies looking at these ingreedients only effect of supp over short time periods
~ humans = glucosamine and chondroitin sulphate accumulate in joint tissue over period of weeks
- recommendations are to feed joint supp on daily basis
- likely take weeks before improvements in movement and joint
- no evidence cartilage regenerates in adult horses

18
Q

supp for behavioural issues about

A
  • designed to reduce excitable behaviour and anxiety
  • increasing number on market
  • reflect challenges owner face providing adequate excercise or turn out
  • calming supp not replacement for correct training
19
Q

supp behaviour - magnesium

A
  • Magnesium needed for metabolism of carbohydrates and normal nerve and muscle function
  • Particularly muscle relaxation
  • Magnesium is lost in sweat and urine and deficiency causes nervousness and muscle tremors
  • Used in calming supplements
  • Calmers are designed to be fed everyday or as one off additions to the diet
  • oxide and carbonate used in calmers
  • mag aspartate used in instant syringe calmers
    ~ most rapidly absorbed form of mag
    ~ acts quicker but for shorter time
  • rec amount = 20-23mg/kg BW/day
  • most calmers provide 6-7g mag per day
20
Q

supp behaviour - tryptophan

A
  • essential amino acid
  • must be provided in diet
  • used to form serotonin = neurotransmitter that helps feelings of calmness
  • can be synthetic form as actual tryptophan or natural form in brewers yeast
  • no recomendations for daily feeding rate of tryptophan
  • some effects seen but need fed multiple days
  • no resurch conclusively shown effect on behaviour
21
Q

supp behaviour - b vits/yeast

A
  • b vits needed for norm metabolism of carbohydrates, fats and proteins = production of energy
  • needed for norm muscle and nerve func
  • equids produce own supply b vits during fermentation of forages in hind gut
    ~ nervous/excitable behaviour can upset digestion = reuce production b vits
    ~ feeding dietary supply can help support b vit func
  • brewers yeast = natural source b vits and amino acids
    ~ also synthetic form for guaranteed amounts
    ~ no rec leves except thiamine B1 and Riboflavin B2
  • calming supp take weeks for effect to be seen due to time it can take for changes in behavior
    ~ fear/ecitement remain for some time due to learnt behaviour
22
Q

prebiotics

A

= nutrients that not directly used by equids
- provide food for bacteria in hindgut
- often in form of oligosacharides
~ FOS (fructo-oligosacharides)
~ MOS (mannan-oligosacharides)
* e.g. bio-moss = selectively binds to pathogeneic bac, stops bac bind to intestinal wall and so excreted = reduce no. pathogens in tract
* derived from outer cell wall of S.cerevisiae = beta-glucans known elements able to activate immune sys of animals
- feed good bac and bind to disease causing bac e.g. e.coli and salmonella = maintain gut health
- discussion about continued and periodic feeding
- rec amount = 10g/day per adult horse

23
Q

Probiotics

A

= living microorganisms that positiveley affect the GIT enviro
- live strains of bac or yeast
~ many supp use Yea-sacc
- no live bac approved for use in uk (only yeast)
- some discussion about periodic or continued feeding
- rec amount = 10g/day per adult horse

24
Q

inclusion and feeding rate

A
  • when comparing or evaluating supp = need to calculate feeding rate of active ingreedients to determine if effective and its economic value
25
Q

inclusion and feeding rate

A
feed = how much given to horse
incl = how much nutrient is in certain amount of product
  • when comparing or evaluating supp = need to calculate feeding rate of active ingreedients to determine if effective and its economic value
26
Q

Charcoal

A
  • used when eaten something toxic
  • binds with toxins and expelled
  • used in equids with diarrhoea to firm up loose droppings or those with endotoxeaimia (blood poisoning)
  • not absorbed so safe to introduce suddenly in diet
  • should not be fed continuously for long periods = influence absorption of other nutrients
  • feed for 1 week then discontinue
    ~ if still has issues and need to look at diet
    ~ need to find cause of digestive upset
27
Q

Look into for following supp

  • review evidence support use certain ingredients
  • critique supp on market with examples of good and bad (active ingredient, daily feed rates, cost per day)
A
  • hoof supp
  • digestive supp (hind gut)
  • resp supp