Flashcards in supportive care Deck (12)
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1
for F+N which patients would you consider adding vancomycin?
-AML patients receiving high dose cytarabine, due to risk of S.viridans infection associated with septic shock and ARDS
-presented with hypotension/shock
-mucositis
-prior history of alpha hemolytic strep infection
-colonization with resistant bugs
-vegetations on echo
2
for F+N when would you consider adding flagyl?
-typhlitis
-significant mucosal breakdown
-perianal skin breakdown
-c-diff infection
-peritoneal signs or other abdominal pathology
3
what infections are BMT patients at risk for within the first 30 days post BMT?
gram negatives
staph
aspergillus
candida
HSV-1
4
what infections are BMT patients at risk for within 30-120 days post BMT?
candida
aspergillus
PJP
CMV, adeno, EBV, HHV-6
5
what are three findings on imaging that suggest Invasive fungal infection of lower resp tract?
dense circumscribed lesion with or without halo sign
air crescent sign
cavitation
6
what is the best antifungal to use to treat aspergillus
voriconzole
7
amphotericin does not cover which species of candida the best and is not recommended?
candida albicans
fluconazole is the treatment of choice
8
what is the treatment of choice for mucormycosis
Ampho B
9
for neutropenic patients what is the initial therapy for candidemia?
echinocandin is the therapy of choice
Ampho B is an alternative
10
What are the principles of chemotherapy?
- multi-drug therapy
- neo-adjuvant vs adjuvant therapy
- dose intensity
11
Identify 2 subtle CT signs suggestive of invasive aspergillosis.
- halo sign
- air-crescent sign
12
