Surgery Flashcards

(143 cards)

1
Q

Example of depolarising neuromuscular drug

A

suxamethonium

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2
Q

key adverse events from suxamethonium

A

malignant hyperthermia
hyperkalaemia

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3
Q

reversal agent for malignant hyperthermia

A

IV dantrolene

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4
Q

MoA of suxamethonium

A

binds nACh, constant depolarisation of motor plate through non-competitive agonism

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5
Q

contraindications to suxamethonium

A

penetrating eye injuries
acute narrow angle glaucoma

this drug increases intra ocular pressure

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6
Q

use of suxamethonium

A

rapid sequence intubation

due to rapid onset and short duration of action

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7
Q

examples of non-depolarising neuromuscular blocking drugs

A

Tubocurarine, atracurium, vecuronium, pancuronium

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8
Q

MoA of non depolarising NMDs

A

Competitive antagonist of nicotinic acetylcholine receptors

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9
Q

main adverse effect of non depolarising NMD

A

hypotension

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10
Q

reversal agent for non depolarising NMD

A

neostigmine (Acetylcholinesterase inhibitor)

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11
Q

treatment of local anaesthetic toxicity

A

20% lipid emulsion

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12
Q

symptoms of local anaesthetic toxicity

A

agitation, confusion, dizziness, drowsiness, dysphoria, auditory changes, tinnitus, perioral numbness, metallic taste, and dysarthria

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13
Q

consequences of local anaesthetic toxicity

A

seizures, respiratory arrest, and/or coma.

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14
Q

drugs that can cause ED

A

beta blockers
SSRIs

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15
Q

most common type of prostate cancer

A

adenocarcinoma (95%)

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16
Q

most common type of bladder cancer

A

transitional cell carcinoma

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17
Q

which airway adjunct is suitable for a seizing patient

A

nasopharyngeal

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18
Q

RELATIVE contraindication for nasopharyngeal airway

A

basal skull fracture

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19
Q

what is the main complication of axillary lymph node clearance

A

lymphoedema and functional arm impairment

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20
Q

how is the risk of DVT reduced in superficial thrombophlebitis

A

LMWH

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21
Q

where is the lesion in subclavian steal syndrome

A

proximal stenotic lesion of the subclavian artery results in retrograde flow through vertebral or internal thoracic arteries

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22
Q

main presentation of subclavian steal syndrome

A

syncope

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23
Q

aetiology of aortic coarctation

A

aortic stenosis at site of ductus arteriosus

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24
Q

how does inflammatory breast cancer present

A

progressive erythema and oedema in the absence of signs of infection such as WCC or CRP, fever or discharge

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25
what size lump is the cut off for wide local excision
< 4cm
26
what size lump is the cut off for mastectomy
> 4cm
27
first line treatment of lactational mastitis
12-24 hours of effective milk removal i.e. continue breastfeeding don't start Abx just because they present after one day of symptoms
28
features of duct ectasia
nipple retraction milky or cheesy or green discharge
29
describe the breast screening programme in the NHS
for women between 50 to 70, screened every 3 years Over 70s are usually not invited but can request screening via their GP
30
what is the chemotherapy treatment for node positive breast cancer
FEC-D chemotherapy
31
what is the chemotherapy treatment for node negative breast cancer requiring chemo
FEC chemotherapy
32
first line mx of patient with mild symptoms related to varicose veins [4]
elevate legs compression stockings lose weight regular exercise
33
key investigation of varicose veins
venous duplex ultrasound demonstrates retrograde flow
34
when should varicose veins be referred to vascular [5]
significant/troublesome lower limb symptoms e.g. pain, discomfort or swelling previous bleeding from varicose veins skin changes secondary to chronic venous insufficiency (e.g. pigmentation and eczema) superficial thrombophlebitis an active or healed venous leg ulcer
35
what are the surgical treatments for varicose
endothermal ablation: using either radiofrequency ablation or endovenous laser treatment foam sclerotherapy: irritant foam → inflammatory response → closure of the vein surgery: either ligation or stripping
36
4 skin changes associated with varicose veins/chronic venous insufficiency
varicose eczema (also known as venous stasis) haemosiderin deposition → hyperpigmentation lipodermatosclerosis → hard/tight skin atrophie blanche → hypopigmentation
37
what poses the greatest risk to developing TRALI
infusion with plasma components
38
what is normal CVP
In a healthy adult, the normal range for CVP is typically between 2 to 8 mmHg (millimeters of mercury) when measured at the end of expiration while the individual is at rest and in a supine (lying down) position.
39
signs of bowel perforation what investigation must be done
severe abdominal pain, guarding, and rigidity. An erect chest X-ray is the most appropriate initial imaging study for suspected bowel perforation because it can detect free air under the diaphragm (pneumoperitoneum)
40
what are the indications for thoracotomy in haemothorax
>1.5L blood drained initially or losses of >200ml per hour for >2 hours
41
which congenital hernias can be managed conservatively and which ones need repair ASAP
conservative for umbilical till 4-5years old repair for inguinal
42
examples of benign liver lesions [8]
hemangiomas Liver cell adenoma Mesenchymal hamartomas Liver abscess Amoebic abscess Hyatid cysts Polycystic liver disease Cystadenoma
43
which nerve is at risk of damage when doing a carotid endarterectomy how does damage present?
hypoglossal It presents as ipsilateral tongue deviation towards lesion.
44
preferred method of detecting free air in the abdomen
CT abdo
45
difference between incarcerated and strangulated hernias
strangulated ones are painful unlike incarcerated hernias
46
what is the general treatment of inguinal hernias
treat medically fit patients even if they are asymptomatic i.e. refer routinely to open mesh repair
47
how are surgically unfit patients treated for inguinal hernias
a hernia truss
48
how are unilateral inguinal hernias treated compared to bilateral hernias | surgical approach
unilateral inguinal hernias are generally repaired with an open approach bilateral and recurrent inguinal hernias are generally repaired laparoscopically
49
Parkland formula for burns fluid resus how is resus fluid distributed over the 24 hours
SA% x body weight x 4ml gives fluid replacement over 24 hours 50% over the first 8 hours 50% over the next 16 hours
50
which fluids are used in burns resus
crystalloids only Hartmans and Ringers
51
what fluids are used in burns resus after 24 hours
colloids including albumin and FFP
52
which analgesia should be avoided post kidney transplant
NSAIDs
53
What should you do to ascertain the anatomy and subtype of inguinal swelling?
press on the deep inguinal ring and ask the patient to cough
54
where in the body should lidocaine never be used
it must never be used near extremities due to the risk of ischaemia
55
radiological sign indicating free air in the abdomen
rigler's sign
56
nerve lesion due to Posterior triangle lymph node biopsy
accessory nerve lesion
57
nerve lesion due to Lloyd Davies stirrups
common peroneal nerve
58
nerve lesion due to Thyroidectomy
laryngeal nerve
59
nerve lesion due to Anterior resection of rectum
hypogastric autonomic nerves
60
nerve lesion due to Axillary node clearance
long thoracic nerve, thoracodorsal nerve and intercostobrachial nerve
61
nerve lesion due to Inguinal hernia surgery
ilioinguinal nerve
62
nerve lesion due to Varicose vein surgery
sural and saphenous nerves
63
nerve lesion due to Posterior approach to the hip
sciatic nerve
64
what size fibroadenoma is surgically excised
>3cm or causing discomfort and pain
65
what is Whipple's procedure for
pancreatic tumours
66
management of those who've always had difficulties maintaining an erection
routine referral to urology
67
how can you check for rectal anastomotic leak
gastrograffin enema
68
treatment of acute anal fissure
1) soften stool dietary advice: high-fibre diet with high fluid intake 2) bulk-forming laxatives are first-line - if not tolerated then lactulose should be tried 3) lubricants such as petroleum jelly may be tried before defecation 4) topical anaesthetics 5) analgesia
69
treatment of chronic anal fissure
- use acute treatment - 1st line: topical glyceryl trinitrate (GTN) if topical GTN is not effective after 8 weeks then secondary care referral should be considered for surgery (sphincterotomy) or botulinum toxin
70
type of resection for Caecal, ascending or proximal transverse colon
right hemicolectomy
71
type of resection for Distal transverse, descending colon
left hemicolectomy
72
type of resection for Sigmoid colon
high anterior
73
type of resection for Upper rectum
anterior resection
74
type of resection for Lower rectum
anterior resection (low TME)
75
type of resection for Anal verge
Abdomino-perineal excision of rectum
76
management of caecal volvulus
right hemicolectomy
77
management of sigmoid volvulus
rigid sigmoidoscopy with rectal tube insertion
78
when is a Hartmann's procedure done
emergency resection of bowel especially perforation
79
main investigation for diffuse axonal injury
MRI brain
80
appearance of ileostomy
spouted
81
appearance of colostomy
flushed
82
outputs of ileostomy
liquid
83
outputs of colostomy
solid
84
main investigation for chronic pancreatitis
CT abdo
85
monitoring for risk of diabetes in someone with chronic pancreatitis
annual HbA1c
86
treatment of post op ileus
NBM and NG tube
87
at which positions do haemorrhoids develop
3,7 and 11 o clock
88
treatment of refractory crohns
infliximab
89
position of anal fissures
6 and 12 o clock
90
staging of oesophageal or gastric cancer
CT
91
most common cause of chronic pancreatitis
chronic alcohol
92
treatment of Gastric MALT lymphoma
treat the H.pylori with triple therapy will respond if low grade
93
head trauma related causes of third nerve compression
extradural bleed transtentorial herniation
94
treatment of thrombosed haemorrhoids
if presenting within 72 hours of onset of pain --> Surgery Beyond 72 hours --> conservative management
95
how does a thrombosed haemorrhoid present
typically present with significant pain and a tender lump examination reveals a purplish, oedematous, tender subcutaneous perianal mass
96
diagnostic investigation of boerhaaves syndrome
CT contrast swallow
97
treatment of boerhaaves
Treatment is with **thoracotomy and lavage**, if less than 12 hours after onset then primary repair is usually feasible, surgery delayed beyond 12 hours is best managed by insertion of a T tube to create a controlled fistula between oesophagus and skin.
98
what may be observed in the chest wall of someone with boerhaaves
Subcutaneous emphysema presents as crepitus
99
which stoma is usually used after rectal cancer surgery
loop ileostomy
100
4 risk factors of atherosclerotic vascular disease
smoking HTN hypercholestrolaemia DM
101
how does intermittent claudication present?
pain after walking. Gripping, tightening, burning pain in thighs, buttocks.
102
intermittent claudication vs spinal stenosis
spinal stenosis pain is worse at rest and better with exercise.
103
most common location of varicoceles
left side (80%)
104
investigation of varicoceles
ultrasound with Doppler studies
105
what does RUQ pain with bilious fluid in abdominal drain suggest
biliary leak usually post cholecystectomy
106
which renal stones are semi opaque
cystine stones
107
how does Pagets disease of the breast present
Reddening and thickening of nipple and areola weeping, crusty lesion nipple when areola is spared sometimes
108
adverse effects of aromatase inhibitors [4]
osteoporosis: NICE recommends a DEXA scan when initiating a patient on aromatase inhibitors for breast cancer hot flushes arthralgia, myalgia insomnia
109
MoA of aromatase inhibitors
reduces peripheral oestrogen synthesis
110
what should patients with PAD be started on [2]
statin e.g. atorvastatin 80mg and clopi naftidrofuryl oxalate (in those with poor quality of life)
111
what size segment should endovascular revascularization be used for in severe PAD/CLI
<10cm /short also aortic iliac disease and high-risk patients
112
what size segment should surgical revascularization be used for in severe PAD/CLI
>10 cm /long also multifocal lesions, lesions of the common femoral artery and purely infrapopliteal disease
113
1st line management of PAD
supervised exercise programme
114
what does surgical revascularisation in PAD consist of [2]
surgical bypass with an autologous vein or prosthetic material endarterectomy
115
what does endovascular revascularisation in PAD consist of
percutaenous transluminal angioplasty +/- stent placement
116
women with no palpable axillary lymphadenopathy at presentation should have a ...{investigation} what if this investigation is negative....
pre-operative axillary ultrasound before their primary surgery if negative then they should have a sentinel node biopsy to assess the nodal burden
117
when is axillary node clearance indicated
when there is palpable axillary lymphadenopathy
118
The 'snowstorm' sign on ultrasound of axillary lymph nodes indicates ....[pathology]
extracapsular breast implant rupture. due to leakage of the silicone, which then drains via the lymphatic system, giving the 'snowstorm appearance' both in the breast and the lymph nodes.
119
diagnosis of Pagets disease of the breast [3]
Diagnosis is made by punch biopsy, mammography and ultrasound of the breast.
120
treatment of Raynaud's disease
calcium antagonists
121
Dukes classification for colorectal cancer (A-D)
Tumour confined to the mucosa Tumour invading bowel wall Lymph node metastases Distant metastases
122
indication for CT head within the hour
GCS < 13 on initial assessment GCS < 15 at 2 hours post-injury suspected open or depressed skull fracture any sign of basal skull fracture (haemotympanum, 'panda' eyes, cerebrospinal fluid leakage from the ear or nose, Battle's sign). post-traumatic seizure. focal neurological deficit. more than 1 episode of vomiting
123
features of biliary colic
colicky right upper quadrant abdominal pain worse postprandially, worse after fatty foods the pain may radiate to the right shoulder/interscapular region nausea and vomiting are common in contrast to other gallstone-related conditions, in biliary colic there is no fever and liver function tests/inflammatory markers are normal elective lap chole
124
what BMI can be referred straight to bariatric surgery
>50 >35 if weight is causing/affecting a medical condition
125
where do Lynch syndrome tumours tend to be found
ascending colon and hepatic flexure
126
complications of NG feeding
diarrhoea aspiration hyperglycaemia refeeding syndrome
127
what agent causes hydatid cysts where is it endemic to
Echinococcus granulosus Mediterranean and Middle Eastern countriesin
128
investigation of hydatid cysts
USS --> CT abdo to differentiate between pyogenic and amoebic cysts serology remove surgically
129
amoebic abscess
Liver abscess is the most common extra intestinal manifestation of amoebiasis Between 75 and 90% lesions occur in the right lobe Presenting complaints typically include fever and right upper quadrant pain Ultrasonography will usually show a fluid filled structure with poorly defined boundaries Aspiration yield sterile odourless fluid which has an anchovy paste consistency Treatment is with metronidazole
130
hemangioma
Most common benign tumours of mesenchymal origin Incidence in autopsy series is 8% Cavernous haemangiomas may be enormous Clinically they are reddish purple hypervascular lesions Lesions are normally separated from normal liver by ring of fibrous tissue On ultrasound they are typically hyperechoic
131
liver mass associated with COCP use
liver cell adenoma
132
Solitary rectal ulcer
Associated with chronic straining and constipation. Histology shows mucosal thickening, lamina propria replaced with collagen and smooth muscle (fibromuscular obliteration)
133
Dermatofibroma
Solitary dermal nodules Usually affect extremities of young adults Lesions feel larger than they appear visually Histologically they consist of proliferating fibroblasts merging with sparsely cellular dermal tissues
134
triad of gastric volvulus
vomiting, pain and failed attempts to pass an NG tube
135
McEvedy's
Groin incision e.g. Emergency repair strangulated femoral hernia
136
Lanz
Incision in right iliac fossa e.g. Appendicectomy
137
Gable
Rooftop incision
138
The H causes of pancreatitis
Hypertriglyceridaemia Hyperchylomicronaemia Hypercalcaemia Hypothermia
139
emergency surgery in fulminant UC
subtotal colectomy
140
Gingko leaf sign post laparoscopic surgery
subcutaneous emphysema If the anterior chest wall is affected air can outline the pectoralis major muscle, giving rise to the 'ginkgo leaf' sign.
141
treatment of fissure in any
Stool softeners, topical diltiazem or GTN, botulinum toxin, Sphincterotomy
142
infectious disease that causes sigmoid volvulus
Chagas disease
143