Surgery Flashcards
(143 cards)
Example of depolarising neuromuscular drug
suxamethonium
key adverse events from suxamethonium
malignant hyperthermia
hyperkalaemia
reversal agent for malignant hyperthermia
IV dantrolene
MoA of suxamethonium
binds nACh, constant depolarisation of motor plate through non-competitive agonism
contraindications to suxamethonium
penetrating eye injuries
acute narrow angle glaucoma
this drug increases intra ocular pressure
use of suxamethonium
rapid sequence intubation
due to rapid onset and short duration of action
examples of non-depolarising neuromuscular blocking drugs
Tubocurarine, atracurium, vecuronium, pancuronium
MoA of non depolarising NMDs
Competitive antagonist of nicotinic acetylcholine receptors
main adverse effect of non depolarising NMD
hypotension
reversal agent for non depolarising NMD
neostigmine (Acetylcholinesterase inhibitor)
treatment of local anaesthetic toxicity
20% lipid emulsion
symptoms of local anaesthetic toxicity
agitation, confusion, dizziness, drowsiness, dysphoria, auditory changes, tinnitus, perioral numbness, metallic taste, and dysarthria
consequences of local anaesthetic toxicity
seizures, respiratory arrest, and/or coma.
drugs that can cause ED
beta blockers
SSRIs
most common type of prostate cancer
adenocarcinoma (95%)
most common type of bladder cancer
transitional cell carcinoma
which airway adjunct is suitable for a seizing patient
nasopharyngeal
RELATIVE contraindication for nasopharyngeal airway
basal skull fracture
what is the main complication of axillary lymph node clearance
lymphoedema and functional arm impairment
how is the risk of DVT reduced in superficial thrombophlebitis
LMWH
where is the lesion in subclavian steal syndrome
proximal stenotic lesion of the subclavian artery results in retrograde flow through vertebral or internal thoracic arteries
main presentation of subclavian steal syndrome
syncope
aetiology of aortic coarctation
aortic stenosis at site of ductus arteriosus
how does inflammatory breast cancer present
progressive erythema and oedema in the absence of signs of infection such as WCC or CRP, fever or discharge