Surgery 3. Malignant Pancreatic Disorder Flashcards

1
Q
Pancreatic ductal adenocarcinoma 
Risk factor :- 
Not a risk factor :- 
MC gene mutated :- 
MC histologycal type :- 
Periampullary cancer 
Group of ,,,,cancers situated within ,,,,cm of ampullary opening :- 
1. 
2. 
3. 
4. 
MC is :-
A

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2
Q

MC presentation of CA of head off pancreases & periampullary CA :-
1.
2.

A

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3
Q
Courvoisers laws :- 
Exception to courvoisers law :- 
1. 
2. 
3. 
PNS seein pancreatic cancer :-
A

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4
Q
IOC for CA pancreas :- 
On MRCP/ERCP :- 
X-ray show :- 
Duodenography shows :- 
IOC for staging :-
A

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5
Q
CA pancreases imaging signs 
On ERCP :- 
1. 
2. 
On barium meal 
1. 
2. 
3.
A

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6
Q

Best Tumor marker for CA pancreases :-

A

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7
Q

Best method to obtain tissue diagnosis in CA pancreases :-

A

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8
Q

Staging of CA pancreases :-

A

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9
Q

Management of CA pancreases based on

  1. Coeliac axis
  2. Superior mesenteric artery involvement :-
  3. SMV-PV junction :-
  4. Common hepatic artery :-

Resectable tumor :-
Borderline resectable :-
Unresectable :-

A

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10
Q

Surgery

  1. In tail or body :-
  2. In head :-
    a.
    b.

Surgery of choice for CA head of pancreases :-

A

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11
Q
Whipples procedure 
Aka :- 
Aka :- 
Done only if 
1. 
2. 

Things removed in whipples procedure

Complication of whipples :-
MC complications :-
MC cause of death :- ,,,,,,,,MC in ,,,,,,,,
MC surgical complication :-

A

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12
Q

Kochers Manuer :-

A

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13
Q

Modified whipples :-
Aka :- PPPD
Aka :-

Incision given :-

Removal of
1.
2.
3.

A

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14
Q
Chemotherapy in CA pancreases:- 
Nodal disease present :- 
T3/T4 :- 
Radiotherapy:- 
Most important prognostic factor :-
A

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15
Q

Unresectable :- palliative in nature :-
Jaundice + pruritis :-
Jaundice + gastric outlet obstruction:-
Pain :-

Triple bypass include
1,
2,
3,

A

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16
Q

Cystic neoplasm of pancreas,-
1.
2.

A

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17
Q
More common in :- 
Age of female :- 
CEA :- 
Cells :- 
Cyst structure :- 
Locual :- 
Nature :- 
CT scan:- 
Management :-
A

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18
Q
Introduction papillary mucinious neoplasm 
IPMN 
Sex :-
Triad for diagnosis :- ,,,,,,,,,,,triad 
1. 
2. 
3. 
Site mc :- 
Enzymes elivated :- 

Management l
Observation when :-
Respected when :-

A

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19
Q
Insulinoma 
MC endocrine tumor of pancreases 
Cells :- 
Distribution:- 
Nature :- 
Encapsulated
A

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20
Q

Triad of insulinoma is :-

A

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21
Q
Whipples triad is for 
1. 
2. 
3. 
Gold standard for insulinoma :- 
1. 
2. 
C peptide analysis :- 
Localization best inv is :- 

Management

  1. Enucleation when :-
  2. If malignant than :-

Drug that decrease insulin secretion ,-

A

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22
Q

Gastrinomas
Aka :-
MC pancreatic endocrine tumor in MEN 1 syndrome :-
MC site :-

Gastrinoma triangle aka ,,,,,,,,,,triangle :- 
1. 
2. 
3. 
Gastrinomas which lies outside :- 
% of malignant :- 
CF :- 
Zollinger Ellison triad
1. 
2. 
3. 
MC symptom 
Cause :- 
Asso with :- 
1, 
2, 
3. 
4. 
Diagnosis 
Serum gastrin level :- 
If less than :- 
Give :- 
Value :- 
Gastric ph :- 
Basal gastric output :- 

Localisation using :-
Best :-
All pt of zes should be tested for :-

Management 
Enucleation when :- 
Remove full wall thickness when :- 
Unresectable 
1,
2.
3. 

Pancreatic ZER :- large tumor :
If resectable : -

A

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23
Q
Glucagnoma.:-
Tumor of :- 
Leads to :- 
1. 
2. 
3.
4.
A

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24
Q
VIPoma 
Nature :- 
WDHA syndrome aka :- 
WD :- 
H:-
A:- 

Site :-

A

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25
Q

Non functional pancreatic endocrine neoplasm :-
MC site :-
Nature :-
CF :-

Difference between functional and non functional

Management:- 
MC site of metastasis:- 
Metastatic disease :- 
1. 
2.
A

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26
Q
Difference between pancreatic CA vs nonfunctional tumors 
Size :-
Marker :- 
Imaging feature :- 
Somatostatin receptor syntigraphy : -
A

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