Sweatman: Alternative Therapies Flashcards
(38 cards)
natural drugs linked to liver damage
Kava
comfrey
retail vs non-retail
non-retaile MUCH more likely to report adverse effects, interactions, warnings and recommendations to discuss with provider
and more often include citations from medical literature
HERBALS affecting coagulation status
coumarin derivatives-> anise, celery, chamomile, fenugreek, red clover
natural sialcylates-> meadowsweet, poplar, willowbark
Antiplatelet action-> garlic, gingko biloba
hypercoagulability–> short lived fibrinolytic action
capiscum
known prescription drug interactions
bitter orange-1a2 echinacea-1a2 gingko biloba-2d6 ginseng-2d6 St. Johns wort-3A4, 2C9
antagonize immunosupressants like azathioprine, corticosteroids, cyclosporine, tacrolimus
echinacea
ginseng
stimulant effects may oppose sedatives and produce additive actions with epi, phentamine, pseudoehpedrine, nictoine or amphetimine
caffeine and green tea
estrogen like compounds
could increase risk of cancer in uterus
possible breast and other hormone sensitive cancers
red clover
mean PSA doubling time increased
pomegranite juice
cyp3a4 inhibitor, increases rhabdomyolysis with statins
pomegranate juice
can cause pseudoaldosteronism
hypokalemia esp with diuretics and steroids, hypertnension, preterm labor
licorice root
-innapropriate stimulation of mineralocorticoid receptor by cortisol
DGL -fewer symptoms
non-prescription stimulant laxative-FDA approved
senna
overuse may cause hypokalemia and dehydration
overuse of senna
hypokalemia and dehydration
decrease absorption of other drugs-BC pills, estrogens, digoxin
prevention of UTI or H pylori, prevent dental plaques
cranberry -MAY PREVENT E COLI FROM CLINGING TO THE WALLS
vitamins easily absorbed but not stored in the body
water soluble-renally eliminated
these are the B vitamins
fat soluble vitamins-absorbed with bile acids and are stored for use as needed
ADEK
acute renal failure requiring dialysis
vitamin C
birth defects, liver problems, osteoporosis
vitamin A
-exacerbated by ETOH and high cholesterol
constiupation, weight loss, arryhtmia, calcium and phosphorous deposition in soft tissue
vitamin D
antagonixe warfarin anticoagulant
Vitamin E and K
omega 3 fatty acids
slight dec in BP, high intake required causing increase bleeding
increase HDL and INCrease LDL
dec risk fo second MI, and death from any cause
dec risk of Alzheimers, dec risk of CV disease, protection from cyclosporine toxicity, improvement in Rhematoid arthritis
COq10,
antioxidant lowers BP increased HDL and dec heart disease prevent statin induced myopathy well tolerated
may reduce warfarin activity
inneffective glucosamine
hydrochlorite
glucosamine works for
joints
may increase INR
melatonin made from
serotonin-tryptophan