Swine Dr. Bennett Flashcards

1
Q

General considerations of pig anesthesia

A

certain breeds are prone to malignant hyperthermia:

Landrace

Large White

Peitrain

Poland-China

difficult to restrain

poor venous access

more challanging to intubate

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2
Q

How long to withhold food in pigs

A

6-12 h adults

most anesthetics are “off label”

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3
Q

IM drug admin in pigs

A

need long needle due to significant SQ fat

3-4cm (1.5”) needle

Best in neck caudal to ear & 5 cm from dorsal midline

Do not inject into hindlimb mm.

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4
Q

Where to place IVC in pigs

A

aruicular v.

cephalic v.

can use EMLA cream prior to IVC placement

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5
Q

What drug is used for sedation & premed of pigs

A

Azaperone - butyropenone class

may be combined w/ opioids & ketamine

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6
Q

Azaperone

A

dose related sedation

may cause excitement

dopamine antagonist (like aceprom)

resp & CV effects minimal

BP can fall via alpha1 blockade

  • classified as tranquilizer & antianxiety drug*
  • potent antiemetic*

mediated through via dopamine receptors in CRTZ

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7
Q

What alpha 2 agonist can be used in pigs

Reversal drug

A

Xylazine

Detomidine

Dexmedetomidine ($$$)

pigs less sensitive to alpha2 vs other spp

Atipamezole for reversal

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8
Q

What benzos & dissociative drugs can be used in pigs

A

diazepam + ketamine

midazolam + ketamine (IM)

climazolam+azaperon+ketamine

  • reverse w/ sarmzenil*
  • In US:*

zolazepam + tiletamine IM

small vol needed, rapid onset, very efficatious

incr dose, incr duration & recovery time

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9
Q

Intubation of pigs

A

topical local to reduce risk of laryngospasm

have a selection of tubes available - airway relatively narrow for bodyweight

stylet associated risk of penetrating airway

ensure ETT isn’t to long

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10
Q

Anes maintenance in pigs

A

isoflurane

sevoflurane/desflurane

halothane has risk of malignant hyperthermia

TIVA:

Propofol CRI

Triple Drip (GG+xylazine+ketamine)

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11
Q

monitoring anes in pigs

A

Arterial BP

doppler, oscillometry for non-invasive

for invasive use auricular art.

ETCO2, ETAA, FiO2

Temperature: important for detection of hyperthermia or hypothermia

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12
Q

analgesia in pigs

A

NSAIDs : Meloxicam, Carprofen

Opioids: fairly insensitive to effects but there are published doses

drug withdrawal requirements

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13
Q

local anes in pigs

A

lumbosacral epidural for C-section, castration

use stifle as landmark

Lidocaine: dose varies by size

can use combo of Alpha2 agonist & lidocaine

(xylazine+lidocaine)

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14
Q

recovery in pigs

A

risk of laryngospasm

airway obstruction

prone to hypothermia due to lack of furry coat

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15
Q

Malignant hyperthermia

A

rare inherited condition

due to mutation of the ryanodine Ca2+ release channel in sarcoplasmic reticulum

Suxamethonium & halothane most commonly inplicated

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16
Q

CS of malignant hyperthermia

A

rapid incr ETCO2

muscle rigidity

dramatic incr in body temp

tachypnea→dyspnea→apnea

hypoxia, cyanosis

incr lactate production

metabolic acidosis

myoglobinuria

arrhythmias

17
Q

Tx for malignant hyperthermia

A

stop admin of inhalant gas!

change breathing system or switch to clean machine

cool down

intracellular MNBD (dantrolene)

sodium bicarb to tx metabolic acidosis

maintain normal ventilation