Sympathomimetics Flashcards

(47 cards)

1
Q

Methoxyamine

A

alpha-1 agonist

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2
Q

Alpha-1 agonist MOA

A

Increases vasoconstriction peripherally
Increases pressures
May not impact CO

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3
Q

Alpha-1 Agonist Clinical Use

A

Hypotension

Shock

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4
Q

Alpha-2 Agonist MOA

A

Increases vasoconstriction if used locally

Decreases NE release systemically (Reduce sympathetic outflow)

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5
Q

Alpha-2 Agonist Clinical Use

A

Treat hypertension (esp. in pregnancy)

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6
Q

Alpha-methyldopa

A

Alpha-2 agonist

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7
Q

Beta-1 Agonist MOA

A

Increases sympathetic outflow
Increased CO
Increased renin production

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8
Q

Beta-1 Agonist Clinical Use

A

Treatment of heart failure and cardiogenic shock

Increase CO

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9
Q

Dobutamine

A

Beta-1 Agonist

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10
Q

Beta-2 Agonist MOA

A

Increases sympathetic outflow

Bronchodilation

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11
Q

Beta-2 Agonist Clinical Use

A

Asthma
COPD
Obstructive Lung Disease

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12
Q

Metaproterenol

A

Beta-2 Selective Agonist

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13
Q

Albuterol

A

Beta-2 Selective Agonist

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14
Q

Terbutaline

A

Beta-2 Selective Agonist

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15
Q

Salmeterol

A

Beta-2 Selective Agonist

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16
Q

Formoterol

A

Beta-2 Selective Agonist

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17
Q

Isoproterenol

A

Non-selective Beta Agonist

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18
Q

Epinephrine

A

Catecholamine

a1=a2; b1=b2

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19
Q

Epinephrine Uses

A

Asthma (b2)

Anaphylaxis (b2, b1, a1)

20
Q

Norepinephrine

A

Catecholamine

a1=a2; b1»>b2

21
Q

Norepinephrine Uses

A

Cardiogenic shock

22
Q

Dopamine

A

Catecholamine

D»>b»>a

23
Q

Dopamine Uses

A

Shock 2/2 low CO or renal failure

24
Q

Propranolol

A

Non-selective beta antagonist

25
Nadolol
Non-selective beta antagonist
26
Timolol
Non-selective beta antagonist
27
Metapranolol
Non-selective beta antagonist
28
Penbutolol
Non-selective beta antagonist
29
Carteolol
Non-selective beta antagonist
30
Non-selective beta antagonist Uses
Hypertension without asthma/COPD
31
Labetalol
Non-selective beta antagonist with selective alpha-1 antagonism
32
Carvedilol
Non-selective beta antagonist with selective alpha-1 antagonism
33
Beta-1 Antagonism Clinical Use
Reduce angina, improve exercise tolerance post-MI Decrease Cardiac work Renin suppression Antiarrhytmic
34
Acebutolol
Selective B1-antagonist
35
Metoprolol
Selective B1-antagonist
36
Atenolol
Selective B1-antagonist
37
Nebivolol
Selective B1-antagonist
38
Bisoprolol
Selective B1-antagonist
39
Betaxolol
Selective B1-antagonist
40
Esmolol
Selective B1-antagonist
41
SVT Beta blocker
Esmolol
42
Angina Beta Blocker
Metoprolol & Atenolol
43
Acute MI Beta Blocker
Metoprolol & Atenolol
44
Alpha 1 Antagonist Uses
Hypertension | Vasodilator
45
Prazosin
Alpha 1 Antagonist
46
Terazosin
Alpha 1 Antagonist
47
Doxazosin
Alpha 1 Antagonist