systemic bone diseases Flashcards
(39 cards)
Systemic bone disease, also known asmetabolic bone disease, refers to a ___________ group of disorders affecting the skeletal system.
heterogeneous
most common metabolic bone disease, low bone mass and microarchitectural deterioration
osteoporosis
The most important sequelae of osteoporosis is a _____ fracture.
fragility
_______ fracture is as a fracture that occurs when falling from equal to or less than standing height.
fragility
the stage immediately before osteoporosis
osteopenia
1 in __ women and 1 in __ men over the age of 50 will have a fragility fracture (osteoporotic fracture).
2, 4
3 most common sites for osteoporotic fractures
spine, wrist, hip
“Senile” osteoporosis results from
old age
remove bone:
build bone:
remove bone: osteoclasts
build bone: osteoblasts
Primary osteoporosis: most common, due to both ____ and declining ______levels.
age + hormone
Age related is known as senile or type ___ osteoporosis
type II
Osteoporosis from declining hormone levels is known as postmenopausal or ____ osteoporosis.
type I
Men are less likely to be screened and treated appropriately for osteoporosis
True or false
True
Gold standard for diagnosis of osteoporosis before a fragility fracture
DEXA
dual energy x-ray absorptiometry
______hump may result from spontaneous compression fracture in postmenopausal woman in the thoracic spine
dowager’s hump
No evidence that high-intensity exercise, such as running, is superior to low-intensity exercise, such as walking in preventing osteoporosis.
True or False
True
weekly exercise requirement to prevent osteoporosis
30 mins/3 days
mineral and vitamin vital to bone mineral density
calcium + vitamin D
a small tube is inserted into the collapsed vertebra. A balloon is passed through the tube and is inflated to restore height to the vertebra. Cement is then injected into the vertebral body to maintain the height of the vertebra.
kyphoplasty
similar procedure in which the cement is injected, but a balloon is not initially used to expand the vertebra.
Vertebroplasty
most important hormone regulating bone mineral density
parathyroid hormone
occurs when one or several cells in the parathyroid gland lose their ability to be regulated, developing autonomous excessive release of PTH.
primary hyperparathyroidism
Primary hyperparathyroidism (PHPT) is the most common cause of ____calcemia
hypercalcemia
Osteitis deformans AKA
Paget’s disease