Systemic disease and heart Flashcards Preview

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Flashcards in Systemic disease and heart Deck (25):
1

acromegaly

bp↑; lvh; hypertrophic cardiomyopathy; high output cardiac failure; coronary artery disease.

2

amyloidosis

Restrictive cardiomyopathy. Bright myocardium on echo.

3


ankylosing spondylitis

Conduction defects; av block; ar.

4

Behcet's disease

Aortic regurgitation; arterial ± venous thrombi.

5

cushing's syndrome

Hypertension

6

Down's syndrome

asd; vsd; mitral regurgitation

7

Ehlers-Danlos syndrome

Mitral valve prolapse + hyperelastic skin ± aneurysms and gi bleeds. Joints are loose and hypermobile; mutations exist, eg in genes for procollagen (COL3A1); there are 6 types

8


Friedrich's ataxia

Hypertrophic cardiomyopathy, dilatation over time.

9

Haemochromatosis

af; cardiomyopathy

10

Holt-Oram syndrome

asd or vsd with upper limb defects

11

HIV

Myocarditis; dilated cardiomyopathy; effusion; ventricular arrhythmias; sbe/ie; non-infective thrombotic (marantic) endocarditis; rvf (pulmonary hypertension); metastatic Kaposi’s sarcoma.

12

Hypothyroidism

Sinus bradycardia; low pulse pressure; pericardial effusion; coronary artery disease; low voltage ecg.

13

Kawasaki disease

Coronary arteritis similar to pan; commoner than rheumatic fever ([link]) as a cause of acquired heart disease.

14

Klinefelter's syndrome

asd. Psychopathy; learning difficulties; libido↓; gynaecomastia; sparse facial hair and small firm testes. xxy

15

Marfan's syndrome

Mitral valve prolapse; ar; aortic dissection. Look for long fingers and a high-arched palate.

16

Noonan's syndrome

asd; pulmonary stenosis ± low-set ears.

17

PAN

Small and medium vessel vasculitis + angina; mi; arrhythmias; ccf; pericarditis and conduction defects.

18

Rheumatoid arthritis

Conduction defects; pericarditis; lv dysfunction; aortic regurgitation; coronary arteritis. Look for arthritis signs,

19

Sarcoidosis

 Infiltrating granulomas may cause complete av block; ventricular or supraventricular tachycardia; myocarditis; ccf; restrictive cardiomyopathy. ecg may show q waves.

20

Syphilis

Myocarditis; ascending aortic aneurysm.

21

SLE

 Pericarditis/effusion; myocarditis; Libman–Sacks endocarditis; mitral valve prolapse; coronary arteritis

22

Systemic sclerosis

Pericarditis; pericardial effusion; myocardial fibrosis; myocardial ischaemia; conduction defects; cardiomyopathy.

23

THyrotoxicosis

Pulse↑; af ± emboli; wide pulse pressure; hyperdynamic apex; loud heart sounds; ejection systolic murmur; pleuropericardial rub; angina; high-output cardiac failure.

24

Turner's syndrome

Coarctation of aorta. Look for webbed neck. xo.

25

Williams syndrome

Supravalvular aortic stenosis (visuospatial iq↓).