Systems biology of the cell Flashcards
(4 cards)
1
Q
What is differential adhesion hypothesis?
A
- proposes that cell sorting can be explained as driven by differential adhesion between cell types within a tissue
- cells that adhere more form a tissue with higher surface tension
- tissues with different surface tensions will separate
2
Q
What are the basic ingredients for describing a simple cell?
A
- cortical tension
- adhesion-driven tension
- area conservation
3
Q
Describe in silico cells
A
- non-polar
- cells tend to round up alone but acquire honey-comb lattice when in contact with other cells
4
Q
What mediates adherins between cells?
A
cadherins
