T1: intro Flashcards
(8 cards)
1
Q
Structural biology AIM
A
Mechanistic understand of biological structures
2
Q
how?
A
revealing 3d-structure of molecules
and functional characterisation
3
Q
Organism Length scales
A
Organism scale can be very diverse
however BIOLOGICAL MACROMOLECULES OF ALL ORGANISMS ARE IN SAME LENGTH SCALE
4
Q
macromolecular length scale
A
1-50nm
5
Q
1 A
A
= 0.1nm = 100pm
6
Q
Why is resolution important
A
At 30A = low resolution = contourless
inc resolution inc clarity and can see atoms clearly
7
Q
Pseudo Atomic Resolution
A
3.75A or better
8
Q
What behaviour do proteins show? and how can we better represent this?
A
dynamic - rotation of side chains constantly
snapshots»_space; still images
