T2: Pulmonary System (2) Flashcards
(57 cards)
When does shunting occur?
when a portion of the VENOUS blood does not participate in gas exchange
Examples of conditions that may cause anatomic shunting:
- AVMs
- ARDS
- atelectasis
- pneumonia
- pulmonary edema
- pulmonary embolus
- vascular lung tumors
- intracardiac R to L shunt
Does increased FiO2 help when shunting occurs?
No
Does PCO2 change or stay the same when shunting occurs? Why?
stays the same
B/c compensation with increased RR
Venous blood that flows through the lungs w/o being oxygenated due to nonfunctioning alveoli:
intrapulmonary shunting
Intrapulmonary shunting:
____% is abnormal
____% is life-threatening
greater than 10% = abnormal
greater than 30% = life-threatening
What 2 methods can be used to measure shunting?
- Direct measurement
- Estimation
How do we directly measure shunting?
- Give 100% O2 for 15 min
- measure CaO2 and CvO2
CaO2 means ____.
CvO2 means ____.
CaO2 = O2 content of arterial blood CvO2 = O2 content of venous blood
CaO2 - CvO2 normal is ____ ml/dl.
5 ml/dl
How do we estimate shunting?
- PaO2 / PAO2 ratio
- Alveolar-arterial gradient
- PaO2 / FiO2 ratio
What is the A-a gradient?
The alveolar (PAO2) to arterial (PaO2) pressure difference
PAO2 means ____ pressure
PaO2 means ____ pressure
PAO2 = alveolar O2 pressure PaO2 = arterial O2 pressure
Why is the A-a gradient always positive?
You always have more O2 in the lungs than in the body tissue
What is a normal A-a gradient?
10-20 mmHg
increases within this range as the pt ages
What does A-a gradient show?
How efficiently the lung is managing pulmonary capillary O2 and alveolar O2
If the A-a gradient is large, this indicates a dysfunction in the ___.
lung
(it’s not picking up the O2 like it should
Issues that can lead to large A-a gradient:
- V/Q mismatching
- shunting
- diffusion abnormalities
What is the formula to find PAO2?
PAO2 = FiO2 (PB - PH2O) - PaCO2 / RQ
Abbreviation for fraction of inspired oxygen:
FiO2
Abbreviation for barometric pressure. What is normal?
PB
760 mmHg
Abbreviation for pressure of water vapor. What is normal?
PH2O
47 mmHg
Abbreviation for respiratory quotient. What is normal?
RQ
0.8
PaO2 / FiO2 normal value:
greater than 286
the lower the number, the worse the lung function