TABLET, PILLS, SUPPOSITORIES Flashcards Preview

DOSAGE FORMS 2023 > TABLET, PILLS, SUPPOSITORIES > Flashcards

Flashcards in TABLET, PILLS, SUPPOSITORIES Deck (55)
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1
Q

Are solid dosage forms usually prepared with the aid of suitable pharmaceutical excipients.

A

Tablet

2
Q

varies in size, shape, weight, hardness, thickness, disintegration, depending upon the use and method of manufacturing.

A

Tablet

3
Q

Add necessary bulk to a formulation to prepare tablets of the desired size

A

Diluent or Filler

4
Q

Promotes adhesion of the particles of the formulation, allowing granulation to be prepared and maintaining the integrity of the final tablet.

A

Binders or Adhesives

5
Q

Promote breakup of the tablets after administration to smaller particles for drug availability.

A

Disintegrant

6
Q

Prevent material from sticking to the punches and dies.

A

Antiadherents

7
Q

Enhance flow properties of the powder mixture.

A

Glidants

8
Q

To reduce friction during compression.

A

Lubricants

9
Q

2 types of Miscellaneous adjuncts.

A

Flavorants, Colorants

10
Q

3 types of Coating

A

Sugar coated
Film coated
Enteric coated

11
Q

refers to tablets having pieces broken out or chipped, usually around the edges.

A

Chipping

12
Q

Cracked in the center

A

Cracking

13
Q

It occurs when the upper segment of the tablet separates from the main portion of the tablet and comes off as a cap.

A

Capping

14
Q

It is due to the same causes as capping except that the tablet splits and comes apart at the sides and is ejected in two parts.

A

Lamination

15
Q

Molded tablet

A

Tablet triturates

16
Q

small, usually cylindrical, molded, or compressed tablets containing small amounts of usually potent drugs mixed with a combination of sucrose and lactose or any suitable diluent.

A

Tablet triturates or Molded tablets

17
Q

quickly disintegrate in the presence of moisture.

A

Table triturates or molded tablets

18
Q

easily adjust the composition for any number of dosages.

A

Tablet triturates or molded tablets

19
Q

their small size will limit their use to substances effective in small doses.

A

Tablet triturates or molded tablets

20
Q

are generally prepared by mixing the active drug with lactose, dextrose, sucrose, mannitol, or some other appropriate diluent that can serve as the base.

A

Molded tablets

21
Q

Molded tablets are generally prepared by mixing the active drug with ______, ______, ______, ______ or some other appropriate diluent that can serve as the base.

A

Lactose
Dextrose
Mannitol
Sucrose

22
Q

This base must be readily water soluble and should not degrade during the tablet’s preparation.

A

Molded tablet

23
Q

it is the preferred base but mannitol adds a pleasant, cooling sensation and additional sweetness in the mouth.

A

Lactose

24
Q

The base ordinarily used for molded tablet triturates is?

A

Lactose

25
Q

Lactose containing in what percent?

A

10-20% of sucrose

26
Q

Drugs that react chemically with sugars require special bases such as precipitate calcium carbonate, precipitated calcium phosphate, kaolin, or bentonite.

A

Lactose

27
Q

Drugs that react chemically with?

A

Sugars

28
Q

Give 1 advantage of lactose

A

Rapidly absorbed

29
Q

TABLET TRITURATES

Synonym:
Uses:
Method of preparation:
Appropriate container:
Storage condition:
Ingredients:

A

Molded tablets
Tablet excipients (diluent) and sweetener
Wide mouth bottle
Machine molding
Store at room temperature
Lactose, 95% alcohol, API, Moistening Agent

30
Q

solid oral dosage form consist of one or more medicaments incorporated in a small, round, spherical or ovoid mass that are intended for oral administration.

A

Pills

31
Q

formerly the most extensively used oral dosage form, but they have been replaced largely by compressed tablets and capsules.

A

Pills

32
Q

easy to make and compact in quantity.

A

Pills

33
Q

masked bitter or unpleasant tastes and odors.

A

Pills

34
Q

stable for long periods and can be administered in this form if the dose is not too large.

A

Pills

35
Q

What are the 2 types of Pills

A

Compressed pills
Dispensing pills

36
Q

This excipient formed a ______, very adhesive liquid that was usually prepared in advance of compounding the pills.

A

Colorless

37
Q

What are the 4 generic pill excipients?

A

Lactose
Glycerin
Powdered acacia
Benzoic acid

38
Q

used as a preservative and might be omitted if only a small batch of pill mass was being compounded.

A

Benzoic acid

39
Q

What is the active ingredient of pills?

A

Benzoic acid

40
Q

gave mass the appropriate consistency of adhesiveness, firmness and plasticity.

A

Excipient

41
Q

Steps in making pills

A

Hand rolling
Packaging
Forming a mass and kneading using a mortar and pestle

42
Q

What are the 4 classes of pills

A

Parvules
Boluses
Granules
Pills

43
Q

(small pills)-20mg and less potent substance with coloring agents

A

Parvules

44
Q

20 mg to 60mg it contains sugar

A

Granules

45
Q

60mg to 500mg comes in variety of sizes, shapes, coating and color

A

Pills

46
Q

(big pills) 700mg to 2000mg for veterinary use.

A

Boluses

47
Q

MAGNESIUM SULFATE PILLS

Synonyms:
Uses:
Method of preparation:
Appropriate container:
Storage condition:
Ingredients:

A

Epsom salt
Saline laxative
Hand molding
Wide mouth
Place it in tight container store at room temperature
Magnesium sulfate, Hard soap, API, Purified water, Moistening agent

48
Q

Latin word of suppositories

A

Supponere

49
Q

What is supponere means?

A

To place under

50
Q

Solid dosage forms of various weights and shapes, usually medicated, intended for insertion into body orifices.

A

Suppositories

51
Q

What happen to the suppositories after you insert it?

A

Dissolve or melt

52
Q

prepared extemporaneously by incorporating the medicaments into the base and the molten mass is then poured at a suitable temperature into molds and allowed to cool until set.

A

Suppositories

53
Q

3 types of suppositories

A

Rectal, Vaginal, urethral suppositories

54
Q

What are the methods of preparation of suppositories?

A

Hand rolling
Compression
Fusion

55
Q

SUPPOSITORIES

Synonyms:
Latin name:
Uses:
Formulation:

A

Glycerol suppositories
Suppositoria glycerini
Laxative
-glycerin, sodium carbonate, stearic acid, distilled water
Melt molding