TCAs Flashcards
1
Q
Drugs
A
- Amitriptyline
- Clomipramine
- Nortriptyline
- Trimipramine
- Lofepramine
- Imipramine
- Dosalpine
2
Q
Mechanism of action
A
Inhibits the reuptake of serotonin and norepinephrine in presynaptic terminals
3
Q
Contraindication
A
- Acute porphyrias
- Arrhythmias
- Heart block
- Severe hepatic impairment
- Manic phase of bipolar disorder
- Taking MAOI
4
Q
Side effects
A
- Prolonged QT interval
- Anticholinergic syndrome
- Agranulocytosis
- Arrhythmias
- Bone marrow depression
