Temporal & Mechanistic categories of Pain Flashcards

1
Q

What is temporal pain?

A

the duration of the pain

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2
Q

Temporal aspect of pain is important for what?

A

for our understanding and appropriate treatment of pain

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3
Q

Categories of temporal pain?

A

Transient nociceptive pain
Acute pain
Chronic pain

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4
Q

What is transient nociceptive pain?

A

unpleasant sensation in response to noxious stimuli that does not injure tissue

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5
Q

How is transient nociceptive pain categorized?

A

by temporary unpleasant discomfort by noxious stimulus that does not result in tissue damage

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6
Q

What does transient nociceptive pain include?

A
  • first pain (A delta)

- second pain (C fibers)

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7
Q

What serves as an “early warning sign” that alerts the brain to the presence of potentially tissue-damaging events?

A

transient nociceptive pain

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8
Q

What triggers behavior aimed at avoiding harmful stimuli?

A

transient nociceptive pain

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9
Q

What is acute pain?

A

unpleasant sensation in response to tissue injury and/or inflammation

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10
Q

What is recurrent acute pain?

A

pain that returns periodically but in distinct episodes

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11
Q

What type of pain (acute/chronic/transient) is elicited by tissue damage and inflammation that activates nociceptive afferent neurons at the site of local damage?

A

Acute pain

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12
Q

Acute pain:

Local tissue damage and inflammation temporarily alters the response of what?

A

Peripheral nociceptors (peripheral sensitization) as well as their central connections (central sensitization)

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13
Q

What does acute injury-induced physiological changes produce?

A

hypersensitivity

hyperalgesia & allodynia

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14
Q

What happens in acute pain that promotes healing and prevention of further injury?

A

Acute pain signals the presence of tissue damage and activates physiological and behavioral mechanisms

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15
Q

Chronic pain

A

unpleasant sensation that persists longer than 1 month beyond the normal healing period or that is associated with a pathological process

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16
Q

what pain persists after the triggering event has resolved?

A

chronic pain

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17
Q

What pain is associated with a pathology, and can cause continuous pain over months or years?

A

chronic pain

18
Q

Which pain is not understood to have a protective role?

A

chronic pain

19
Q

Following the identification of the temporal category of pain, what else must be determined in order to select the appropriate treatment?

A

determination of the system affected

20
Q

Pain can be broadly classified into two functional categories.

A
  • Nociceptive pain

- Neuropathic pain

21
Q

Is pure psychogenic pain possible?

A

yes, but rare and difficult to differentiate from the psychological component of pain

22
Q

What is nociception pain further divide into?

A

somatic pain
visceral pain
inflammatory pain

23
Q

Nociception of the mechanistic categories of pain occurs following….

A

mechanical, thermal, or chemical noxious stimulus

24
Q

Nociception subcategories must be determined for proper what?

A

diagnosis and treatment

25
Inflammatory nociceptive pain is associated with the process of tissue repair following what?
tissue damage
26
What is neuropathic pain divided into?
neurogenic and functional pain
27
Which category of mechanistic pain is associated with nervous system disorder?
Neuropathic
28
What does treatment of neuropathic pain depend on?
whether the origin of pain is peripheral (e.g. diabetic neuropathy) or central (e.g. spinal cord injury)
29
Is it possible for a central component of pain to develop following peripheral pain?
yes
30
What is functional neuropathic pain defined as?
a dysfunction of the CNS that results in the excitation of neural systems that can enhance the perception of pain or through the inhibition of endogenous pain modulation system
31
Functional neuropathic pain has a neurogenic component but is better described as a dysfunction of what?
endogenous pain control mechanisms | - i.e. fibromyalgia and post-stroke central pain syndrome
32
Nociceptive: | Somatic (fracture, laceration) responses?
- superficial or deep pain - nociceptive reflex - autonomic response
33
Nociceptive: | Somatic (fracture, laceration) mechanisms?
Mechanical, chemical, or thermal stimulation
34
Nociceptive: | Visceral (colitis) responses?
- constant or cramping - not well localized - autonomic response
35
Nociceptive: | Visceral (colitis) mechanisms?
Distension of viscera
36
Nociceptive: | Inflammatory (arthritis) responses?
- spontaneous pain (diffuse) - hyperalgesia - allodynia
37
Neuropathic: | Neurogenic (neuralgia, spinal injury, thalamic injury, sciatic pain) responses?
- Spontaneous pain (sharp, electrical) - Hyperalgesia - Allodynia
38
Neuropathic: | Neurogenic mechanisms?
Peripheral or central nervous system injury
39
Neuropathic: | Functional (fibromyalgia, post-stroke central pain syndrome) responses?
- Spontaneous pain (diffuse, deep) - Hyperalgesia - Allodynia
40
Neuropathic: | Functional mechanisms?
Hyperactivation or loss of nociceptive tract inhibition