Teratogens- Cole Flashcards Preview

Repro weeks 3-4 Jake > Teratogens- Cole > Flashcards

Flashcards in Teratogens- Cole Deck (27):
1

what marks the time that fetuses are susceptibile to teratogens?

when implantation occurs

2

what is a malformation?

anomalie due to an intrinsic factor

3

what is a deformation?

anomalie due to extrinsic factor

4

what is the dongenital disease associated with cataracts, PDA, microcephaly?

congenital rubella

5

what is the most common fetal infection, characterized by microcephaly, microphthalmia, IUGR?

CMV

6

what is the infection characterized by microcephaly, retinal dysplasia, microphthalmia?

herpes

7

what is associated with limb hypoplasia and muscle atrophy?

VZV

8

what is the triad of toxoplasmosis?

hydrocephalus, calcification in the brain, and chorioretinitis

can also see, mental retardation, microcephaly

9

what are teh characteristcis of syphilis?

dental abnormalities, deafness, skin and bone lesions, mental retardation

10

what type fo problems usually result from fevers and high temperatures?

CNS related, cleft lip /palate

11

what can diazepam cause to fetus?

cleft lip and palate

12

what can streptomycin lead to ?

sensorineural deafness

13

what leads to hypoplastic nose, microcephaly, or hydrocephaly, , seizures...

warfarin syndrome

14

what can anticonvulsants ( valproic acid, diphenylhydantoin lead to?

neural tube defects

15

what is the culprit if you see decrease in oxygen, sodium, potassium, and number of platelets?

thiazide diuretics

16

wehat does thalidomide lead to?

phocomelia

17

what can methotrxate, aminopterin, busulfan ( anti neoplastics) lead to?

microcephaly, cranisynostosis, micrognathia, low set ears, most die in utero or within first year of life

18

what can accutane and rogaine lead to? ( retinoic acid?

trianglular face, craniofacial malformation, heart problems, retardation

19

a mother that is adicted to heroin ( opiate) can do what to the child?

passes on the addiction to opiates to the baby, the baby will show signs of withdrawal

20

what can tobaccoo lead to?

IUGR

21

what are some signs of fetal meth?

shaking and tremors, cerebral injury, fits of rage, coordination problems, cerebral palsy is common

22

what is the most common teratogen?

alcohol

23

what are the features of a fetal alcohol syndrome baby?

short palpebral fissures, flat midface, thin upper lip, epicanthal folds

24

what does DES exposure lead to ?

T shaped uterus, and increased chance of vaginal adenocarcinoma

25

what aer the most common problems with diabetic mothers?

heart and neural tube defects

26

what does obesity increase the chance of?

neural tube defects

27

wat does hypoxia lead to?

cerebral palsy