Term 2 Flashcards

1
Q

Nervous System

A

Controls homeostasis through nerve impulses (action potentials) conducted along axons of neurons. At axon terminals, impulses trigger release of neurotransmitter molecules. The result is either excitation or inhibition of specific other neurons, muscle fibers (cells), or gland cells.

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2
Q

Nervous System

Types of cells of the nervous system

A

Neurons( Nerve cells) Neuroglia

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3
Q

Nervous System

Neurons (nerve cells) properties

A

Excitability: ability to RESPOND to a stimulus

Conductivity: ability to TRANSMIT a signal

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4
Q

Nervous System

Neuroglia properties

A

Specialized cells that support the neurons in some way

Ex. They phagocytize foreign substances, produce cerebrospinal fluid, and form myelin sheaths around axons

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5
Q

Nervous System organization

A

Central nervous system (CNS)

Peripheral nervous system (PNS)

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6
Q

Nervous system organization

Central nervous system (CNS)

A

Consists of the brain & spinal cord which are surrounded and protected by the skull and vertebral column respectively

May be thought of as the central control center of the body, receiving and interpreting or integrating all stimuli and relaying nerve impulses to muscles and glands where the designated actions take place

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7
Q

Nervous system organization

Peripheral nervous system

A

Includes all of the neural tissue outside the CNS. it delivers sensory information to the CNS and carries motor commands to peripheral tissues and systems.

Somatic nervous system (SNS)

Automatic (autonomic) nervous system (ANS)

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8
Q

Nervous system organization

Peripheral nervous system

Somatic nervous system

A

Division of the PNS composed of:

Somatic Afferent SENSORY division - which receives sensory information and conveys it to the spinal cord and brain via nerves.

Somatic Efferent MOTOR division - which regulates the contraction of skeleton via neuronal pathways that descend from the brain and spinal cord to lower motor neurons

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9
Q

Nervous system organization

Peripheral nervous system

Autonomic nervous system

A

Consists of sensory neurons that convey information from receptors in the viscera to the CNS and motor neurons from the CNS that conduct impulses to smooth muscle, cardiac muscle, and glands. Since its motor responses are not normally under conscious control, the ANS is involuntary.

Motor portion: sympathetic and parasympathetic division. With a few exceptions, the viscera receives instructions from both.

Sympathetic neurons - involve expenditure of energy

Parasympathetic neurons - restore and conserve body energy

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10
Q

Nervous System

Neurons - Three principled parts

A

The cell body

Dendrites

An axon

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11
Q

Nervous System

Neurons

Cell body

A

Vary in shape and size Has a large nucleus which contains a nucleolus, as well as several structures that are responsible for metabolism, growth and repair of the neuron - endoplasmic reticulum, lysosomes, mitochondria, neurofilaments, neurotubules, and Golgi apparatus

Neurofilaments: provide a skeletal framework for the axon

Neurotubules: function in the intracellular transport of the proteins and other substances, in both directions between the cell body and the ends of the processes

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12
Q

Nervous System

Neurons

Dendrites

A

Thread-like projections which are actually extensions of the cell body

Conduct nerve impulses towards the cell body

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13
Q

Nervous System

Neurons

Axons

A

A neuron generally has just one axon which extends from the cell body Carries nerve impulses away from the cell body to the next neuron, muscle or gland

Originates from the AXON HILLOCK

The initial segment, the site where the nerve impulse is initiated, lies immediately after the axon hillock

May have side processes called COLLATERAL BRANCHES end in a spray of small axon branches or TELODENRIA which end I tiny swellings called end bulbs

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14
Q

Nervous System

Neurons

Synapse

A

The junction between the end bulb of one axon and the cell body, dendrite, or axon of another neuron

A site where information is transferred from one cell to another

Ex. Neuron, muscle,gland

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15
Q

Nervous System

Neurons

Neurolemmocyte

A

Schwann cells

Form myelin sheaths around axons in the PNS

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16
Q

Nervous System

Neurons

Oligodendryte

A

Form myelin sheaths in the CNS

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17
Q

Nervous System

Myelination of axons

A

Some axons are covered with layers of a lipid sheath called myelin

Myelin sheath is formed by specialized non-neural cells called SCHWANN CELLS in the PNS and OLIGODENROCYTES in the CNS

The outer layer, or sheath, of the cells is the NEUILEMMA sheath

A myelin sheath is segmented, interrupted at regular intervals by gaps called NODES OF RANVIER. The distance between nodes is the INTERNODE.

There are myelinated and unmyelinated axons

A myelinated nerve fiber transmits a nerve impulse faster

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18
Q

Nervous System

Types of Neurons - Structural Classification

Multipolar Neurons

A

Have many processes consisting of many dendrites and a single axon

Ex. association (interneurons) and motor neurons

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19
Q

Nervous System

Types of Neurons - Structural Classification

Bipolar Neurons

A

have two processes: a dendrite and an axon which conducts action potentials to the CNS

Sensory neurons

Relatively Rare but play an important role in relaying information concerning sight, smell, and hearing

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20
Q

Nervous System

Types of Neurons - Structural Classification

Unipolar Neurons

A

Have one process, an axon Most sensory neurons are unipolar

Their peripheral ends have dendrite-like processes that respond to stimuli, producing action potentials that are conducted by the axon to the CNS

The branch that extends from the periphery to the neuron cell body, conducts action potentials to the cell body. According to a functional definition of a dendrite, it could be classified as a dendrite

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21
Q

Nervous System

The Reflex Arc - Location

Afferent Neurons

A

Convey information from the tissues and organs of the body to the CNS

Unipolar neurons are the most common in the PNS

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22
Q

Nervous System

The Reflex Arc - Location

Efferent or Motor Neurons

A

Convey nerve impulses away from the CNS to effectors (muscles and glands)

All motor neurons that control skeletal muscles are multipolar neurons

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23
Q

Nervous System

The Reflex Arc - Location

Interneurons (Association) Neurons

A

Lie between sensory and motor neurons in the neural pathways of the CNS

Responsible for the distribution of sensory information and the coordination of motor activity

Multipolar neurons

24
Q

Endocrine System

A

Releases its messenger molecules, called hormones into the bloodstream. The cardiovascular system then delivers hormones to virtually all cells throughout the body

25
Nervous VS Endocrine The __ system causes muscles to contract and glands to secrete their product VS The __ system alters metabolic activities, regulate growth and development, and guides reproductive processes.
The NERVOUS system causes muscles to contract and glands to secrete their product The ENDOCRINE system alters metabolic activities, regulate growth and development, and guides reproductive processes.
26
Nervous VS Endocrine \_\_ most often produce their effects within a few milliseconds. \_\_ generally take several hours to bring about their responses.
NERVE IMPULSES most often produce their effects within a few milliseconds. HORMONES generally take several hours to bring about their responses.
27
Nervous VS Endocrine The effects of activating the __ system are generally briefer than the effects produced by the __ system
The effects of activating the NERVOUS system are generally briefer than the effects produced by the ENDOCRINE system
28
Endocrine System organization
Endocrine glands Exocrine glands
29
Endocrine System organization Endocrine Glands
Endocrine glands and specific cells are ductless, secreting products called hormones into extracellular spaces from which they enter the blood stream and circulate throughout the body to their target areas
30
Endocrine System organization Exocrin glands
Exocrine gland secretions, such as sweat and salivary glands, empty directly into ducts that transport them to specific locations
31
Endocrine System Hormones
Specialized chemical substances produced and secreted by an endocrine cell or organ Effective only at specific target cells Like neurotransmitters, they influence their target cells by chemically binding to integral proteins or glycoprotein molecules called receptors
32
Endocrine System Hormones Circulating
Hormones that can pass into the blood and act on distant target cells ENDOCRINES
33
Endocrine System Hormones Local
Hormones that act locally without first entering the bloodstream. PARACRINES act on neighboring cells AUTOCRINES act on the same cell that secreted them
34
Endocrine System Chemical Signal Classification Autocrines
Released by cells and have a local effect on the same cell that released it
35
Endocrine System Chemical Signal Classification Paracrine
Released by cells and affect other cell types locally without being transported in the blood
36
Endocrine System Chemical Signal Classification Hormone
Secreted into the blood to reach their target
37
Endocrine System Chemical Signal Classification Neurohormone
Produced by neurons and function like hormones
38
Endocrine System Chemical Signal Classification Neurotransmitter
Released by neurons at a synapse and influences a postsynaptic cell
39
Endocrine System Chemical Signal Classification Pheromone
A chemical signal secreted into the environment that modify the behavior of other individuals
40
Endocrine System Chemical Signal Classification Autocrine example
Prostaglandins
41
Endocrine System Chemical Signal Classification Paracrine examples
Histamine prostaglandins
42
Endocrine System Chemical Signal Classification Hormone examples
Thyroxine Insulin
43
Endocrine System Chemical Signal Classification Neurohormone example
Oxytocin Antidiuretic hormone
44
Endocrine System Chemical Signal Classification Neurotransmitter/neurohumor example
Acetylcholine Epinepherine
45
Endocrine System Chemical Signal Classification Pheromones example
Sex pheromones are released by humans and many other animals. they are released in the urine of animals, such as dogs and cats. Pheromones produced by women influence the length of the menstrual cycle of other women
46
Endocrine System Chemical Classification
Amines Polypeptides and Proteins Steroids Ecosanoids
47
Endocrine System Chemical Classification Amines
Hormones derived from the amino acids Tyrosine and Tryptophan. They include hormones secreted by the adrenal medulla and thyroid Ex. Epinephrine, thyroid hormones, serotonin
48
Endocrine System Chemical Classification Polypeptides and Proteins
Consist of chains of amino acids Synthesized on rough endoplasmic reticulum and exported from the cell Ex. Insulin (pancreas), erythropoietin (kidney), antidiuretic hormone (posterior pituitary)
49
Endocrine System Chemical Classification Steroids
Lipids derived from cholesterol Ex. Testosterone, progesterone, estrogens and cortisol
50
Endocrine System Chemical Classification Ecosanoids
Derived from arachidonic acid, a fatty acid Exert control over many body systems Ex. Thromboxane A2 is made by platelets. it causes vasoconstriction and promotes platelet aggregation. these actions prevent excessive blood loss when a blood vessel is damaged or severed
51
Endocrine System Hormone Transport in Blood Water-soluble
Catecholamines, peptide, and protein hormones are water-soluble hormones They circulate in watery blood plasma, and in free form (not attached to plasma proteins)
52
Endocrine System Hormone Transport in Blood Steroid and Thyroid
On entering the blood, steroid and thyroid hormones attache to specific transport proteins, which are synthesized by the liver. The (shuttle) proteins have 3 functions 1. they improve the transportability of the lipid-soluble hormones by making them temporarily water-soluble 2. retard passage of the small hormone molecules through the filtering mechanisms in the kidney, thus slowing the rate of hormone loss in the urine 3. provide a ready reserve of hormones already present in the bloodstream
53
Endocrine System Mechanism of Action Water-soluble
Peptides, proteins, and catecholamines (water-soluble hormones) exert at least some of their physiological responses through the increased synthesis of cAMP. These include anitidiuretic hormone (ADH), oxytocin (OT), calcitonin (CT), epinepherine, and norepinephrine Besides cAMP, several other substances are known as second messengers. These include calcium ions (Ca2+), cyclic guanosine monophate (cGMP), inositol trisphosphate (IP3) and diacylglycerol (DAG) The hormonal mechanism called the FIXED-MEMBRANE-RECEPTOR MECHANISM, involves the formation of second messengers
54
Endocrine System Mechanism of Action Water-soluble Fixed-Membrane-Receptor Mechanism
Catecholamines, peptides, and proteins hormones are water-soluble. their receptors are integral proteins on the plasma membrane of target cells Since these hormones can deliver their message only to the plasma membrane, they are called FIRST MESSENGER. a SECOND MESSENGER, commonly cyclic (cAMP), is needed to relay the message inside the cell where hormone-stimulated response can take place. cAMP is synthesized from ATP by adenylate cyclase, an enzyme attached to the inner surface of hte plasma membrane. cAMP and other second messengers alter cell function in specific ways. Ex. elevated cAMP increses cardiac muscle contraction
55
Endocrine System Mechanism of Action Lipid-soluble (Steroid and Thyroid)
Because steroid hormones are lipid-soluble and pass easily through the plasma membrane, their receptors are inside the target cells. The hormone mechanism called the MOBILE-RECEPTOR MECHANISM, involves stimulus of protein synthesis. Cortisol, aldosterone, thyroid hormones, testosterone, estrogen and progesterone are mobile-receptor hormones and have their receptor hormones and have their receptors localized in the cytoplasm All other hormones usually use the fixed-membrane-receptor mechanism
56
Endocrine System Control of Secretion Negative Feedback Mechanism
A hormone is release in response to a specific stimulus and usually, its action reverses or negates the stimulus through a negative feedback mechanism Ex. control of insulin secretion by blood glucose levels
57
Endocrine System Control of Secretion Positive Feedback Mechanism
The effect of a positive feedback mechanism is amplification of the stimulus and increasing release of the hormone until a particular process in complete and the stimulus ceases. Ex. during child birth, the hormone oxytocin stimulates contraction of the uterus. uterine contractions, in turn, stimule more oxytocin release.