terms and models TERM 2 Flashcards

(131 cards)

1
Q

reasons for atypical development

A

pre-natal effects
environmental effects
genetic effects - spontaneous mutations
multifaceted effects - ASD, ADHD

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2
Q

Autism and airport bags

A

improved overtime in accurately rejecting bags when target wasn’t present

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3
Q

16p11.2

A

duplication/deletion of certain part of chromosome

varied presentation leads to developmental delay

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4
Q

chromosomes

A

chromsome arm- short = p, long = q

chromosome region - labelled with numbers (lower = closer to centre)

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5
Q

genes

A

DNA lives inside.. > genes (21,000 types) > chromosomes (100/1000s genes) > cell

DNA inside genes inside chromosomes

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6
Q

copy number variants

A

duplicate or deletion

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7
Q

williams syndrome

A

deletion of 7q11.2
1 in 10,000
- distinct facial features, cardiac & cognitive abnormalities, highly sociable personality

cognitive profile:
- strengths in verbal, visuospatial IQ

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8
Q

agent that causes change in embryo

A

teratogen

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9
Q

down syndrome

A

duplicate of 21st chromosome
can be full or partial duplication

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10
Q

physical characteristics of DS

A

short neck
flat face
upward slanting eyes
wide short hands - deep crease
poor muscle tone

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11
Q

cognitive characteristics of DS

A

short attention span
impulsive
slow learning
delayed speech development
variable IQ (30-70)

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12
Q

chromosomes

A

small arm - p
large arm - q

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13
Q

fetal alcohol syndrome

A

alcohol = teratogen (changes embryo)
depends on when during gestation period alcohol is consumed
binge drinking worsens symptoms

ethanol = alters DNA and protein synthesis

Canada - 2-3% of school children

shares impairments with ADHD

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14
Q

intellectual disability

A

affects 1.4%
diagnosis based on IQ tests

classified as:
Mild: 52-69 (IQ)
moderte: 36-51
severe: 20-35
profound: <19

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15
Q

ADHD

A

inattention
hyperactivity and impulsivity

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16
Q

Autism

A

Deficits in social interaction
restricted, repetitive behaviour

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17
Q

atypical development

A

delayed, advanced development
the extremes of individual differences in development

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18
Q

patterns of atypical development

A

typical
delay - attainment gap, develop slower
delay with catchup - same as delay but catch up to advanced
lower starting point - rate of development normal but don’t catch up
advanced - good skill (more typical)

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19
Q

regression

A

skill developing typically then child loses aspect of skill (actively get worse)
seen in language and motor skills
typical in ASD, intellectual disabilties

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20
Q

development across multiple domains

A

social - eye contact, empathy, turn-taking

adaptive behaviour - living skills

cognitive - memory, IQ

physical - microcephaly (smaller head, macrocephaly (large head)

motor skill - balance

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21
Q

vineland adaptive behaviour scales

A

communication - receptive (understanding), expressive (spoken), written

daily living skills - personal, domestic, community (use of time, money)

socialisation - interpersonal relationships, play and leisure, coping skills

motor skills - fine, gross

maladaptive behaviour - internalising, externalising

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22
Q

scoring standardised tests

A

convert raw scores to standard scores against age-gender pp
removes individual differences

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23
Q

investigating atypical development

A

consider performance against appropriate control

investigate developmental trajectories

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24
Q

benefits of standardised scores

A

can standardise performance
easy to interpret
not one set way - allows for comparison

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25
specific experimental designs
face perception ToM response inhibition (go-no go)
26
williams syndrome
genetic test to confirm - blood tests identify absence of ELN gene FISH test - fluorescent in-situ hybridization
27
down syndrome
screening pregnancies - 12 weeks 'combined' test: blood tests and nuchal translucency scan (checks build up of fluid behind the neck) if high risk, given amniocentesis to confirm
28
conditions trickier to diagnose
comorbidity between ADHD and autism - 70% but listed as two separate conditions in DSM-5
29
diagnosing autism
referral then assessment Repetitive movements, use of objects, ritualised patterns and speech Fixated interests that are intensely abnormal Hyper or hypoactivity to sensory input or unusual interest in sensory aspects of the environment PERSISTENT DEFICITS IN SOCIAL COMMUNICATION AND SOCIAL INTERACTION ACORSS CONTEXTS
30
diagnosing ADHD
standardised tests: conners rating scales - 3 forms = parent, teacher, self-report - converted to t-scores strengths and difficulties questionnaire inattention, hyperactivity, impulsivity
31
tools used to diagnose autism
ADOS - autism diagnostic observational schedule = semi-structured interview to study presence/absence of certain behaviours - map behaviours into coding section of the manual and calculate pp score ADI - autism diagnostic inventory M-CHAT screening on children, study = 114x more likely to be diagnosed with autism when screening was positive (may not be accurate)
32
mean age of diagnosis for autism and aspergers
autism - 5.5 years asbergers - 11 years
33
mean age when parents first has concerns
autism - 18 months asperges - 30 months
34
infant siblings approach to autism
1 in 5 children with older sibling with autism will go on to be diagnosed
35
EEG - autism
12 months - low risk group had higher coherence in the brain repeated with same group and found similar results biomarker = level of coherence
36
eye tracking - autism
neurotypical - more time looking at people ASC - looked at geometric patterns
37
fNIRs
optical imaging method light that doesn't exit the cortex has been absorbed main absorber of near-infrared light= Hb infants with higher chance of having ASC (sibling with ASC) had reduced activity in temporal cortex in response to social stimuli
38
prevalence of ASC
2008 - 1 in 88 2010 - 1 in 68 2012 - 1 in 69 2014 - 1 in 58
39
evidence of genetic influence in autism
co-occurence = monozygotic twins = 77%, dizygotic twins = 31% co-occurs with other genetic conditions broad autism phenotype - increase in autistic features seen in MIAFS (multi-incidence of autism families) and SIAFs (single incidence of autism families) AUTISTIC TRAITS TOO MILD TO ALLOW DIAGNOSIS (seen in relatives to autistic person - without diagnosis)
40
sotos syndrome
macrocephaly - advanced bone growth 1 in 14,000 deletions on chromosome 5 including NSD1 gene 83% with sotos score above clinical cut-off for ASC
41
complex genetics in autism
65 different genes associated not one single gene - possible interactions between genes 10-20% of ASC cases are associated to genetic abnormality
42
environmental epidemiology
observation of human populations to infer the environmental cause of a condition important to avoid bad science
43
Wakefield measles
suggested link between autism and MMR vaccine more people then contracted measles no real evidence found in repeat studies with larger sample of 650,000 people
44
environmental facts linked to autism
prenatal viral infection/ stress maternal diabetes/ obesity teratogens pollution pesticide exposure during first 8 weeks of pregnancy parental age
45
Hills criteria of establishing causality
biological gradient temporality strength experimental coherence consistent analogy plausibility specificity = BTSECCAPS using meta-analyses
46
odds ratio
statistical method for understanding association between exposure and outcome OR = 1 - no relationship OR < 1 - negative correlation, greater... leads to less effect of... OR > 1 - positive correlation, greater exposure... leads to greater effect of...
47
gene-environment interaction for autism
alteration to MET gene AND increased exposure to air pollution = increased risk of autism
48
co-production
process of conducting research in partnership with the population you are focusing on levels: consultation - no formal involvement involvement - still largely led by clinicians participate - take part in defined activity co-production 'nothing about us without us'
49
why is co-production used
effective in informing theory and applying to general life good for ethics better insights challenges preconceptions
50
COVID-19 and down syndrome
40+ = 4x more likely to be hospitalised 10x more likely to die decreased disability programmes 33% with DS were more irritable, 52% more anxious and 41% more sad
51
COVID and ADHD
533 parents 34.71% of parents reported worsening in Childs behaviours, 30.96% reported an improvement in behaviour
52
male to female ratio for autism
4:1
53
extreme male brain theory - Baron-Cohen
ASC has typical male profile (low empathy and high systemising) foetal testosterone associated with Individual Differences in eye contact, development and autistic traits in typically developing children
54
gender differences in systemising quotient and empathising quotient
neuro-typical males score higher on systemising autistic females score similar to neurotypical males neuro-typical females score high on empathising autistic male and females score lower
55
ratios for autism in different studies (MALE:FEMALE)
loomed meta-analysis overall = 4.2 to 1 high quality studies = 3.32 to 1 only pp with existing ASC diagnosis = 4.56 to 1 population identifying ASC diagnosis = 3.25 to 1 suggests females have greater risk of having ASC overlooked
56
females and ADHD
3/4 females with ADHD undiagnosed diagnosed on average 5 yrs later than males camouflage scores higher (masking symptoms to fit in) - girls more likely to be inattentive early studies primarily on boys
57
williams syndrome strength - relative (delayed in comparison to neurotypical)
known cause verbal language ability fluency syntax grammar
58
williams syndrome weakness
pragmatics (understanding meaning of words) executive functions - inhibitory control WM visuospatial abilities
59
autism strengths
attentional to detail good visual search skills - good at conjunction and feature search - outperformed neutrotypical regardless of task
60
weakness of autism
unknown cause theory of mind - understanding emotions executive fucntions working memory - research is equivocal
61
PECS
speech and language therapy - help Williams and autism stages: 1. picture exchange - swapping picture for item 2. generalise to others 3. two picture exchnage 4. sentence construction 5. verbs, adjectives 6. answer question 7. commenting
62
play therapy
directive (therapist takes lead) or non-directive (less structured) storytelling, role play etc reduced ADHD and social anxiety - increase social-emotional competency
63
music therapy
better verbal recall when info was sung for those without lessons with training = good recall with spoken info possibly aids verbal working improve concentration
64
applied behavioural analyses
intensive - 40 hrs per week positive conditioning relies on parents to reinforce behaviour outside therapy effectiveness - groups who received therapy outperformed on IQ, non verbal IQ, expressive and receptive language and adaptive behaviour
65
therapies helping Williams syndrome
physiotherapy - help poor muscle tone applied behavioural analyses early start Denver model music and play therapy PECS
66
life expectancy of williams syndrome
similar to neurotypical individuals can be shortened due to comorbid conditions
67
life expectancy of autism
16yrs earlier than neurotypical people rises to 30 yrs earlier when they have intellectual disability
68
autistica
'personal tragedies, public crisis' campaign to revise national strategy supporting autistic adults revised to reduce gap in life expectancy by doing greater research and developing policies/treatment
69
life expectancy of down syndrome
1949 - 12 yrs currently - 60 yrs why? - improvements in living conditions, more than half have congenital heart codnitions
70
williams syndrome - adulthood
study: mean age = 26, mean IQ = 61 almost identical cognitive profile to children with WS stayed low levels of social adaptation, reading, spelling
71
adult life - howling and udwin
Williams syndrome- 79% had heart problems 71% attended college - only 33% attained qualifications 62% still lived with family 51% had depression/anxiety 30% day centres 20% full time educuation still 18% part time employment 16% lived independently 2% residential support 1.6% full time employment
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support in adulthood - WS
limited support for adults 23% of parents dissatisfied with medical help 33% unhappy with educational provision 20% unhappy with workplace assistance
73
adulthood in down syndrome
physical: accelerated ageing (due to elastin), developmental gap widens with age cognitive: memory decline in-line with neurotypical individuals difficulty to properly investigate due to comorbid
74
alzheimers
excessive amounts of two proteins: amyloid and tau (tangles) gene that codes for amyloid is located on same chromosome duplicated in downs syndrome 100% individuals 40+ yrs show plaques associated with Alzheimers
75
Down syndrome and alzheimer's
30-39 yrs - 33% show signs of AD 40-59 yrs - 55% 60+ = 75% age of onset typically 65yr+ in neuro-typical people presents differently
76
causes for lost generation (late diagnosis) - autism
change in diagnostic criteria comorbidity reduced stigma - generational differences better recognition gender differences - camouflaging
77
support after diagnosis as an adult
dissatisfying treatment options limited pathways to speech and language therapy for adults
78
future aims
autism strategy = requirements regarding minimum levels of support superseded by think autism = 15 priority areas for development
79
motivation for studying maths
24% of adults in uk have maths ability lower than threshold to function use maths in daily lives globally: 1/5 adults unable to deal with two step calculations
80
order we learn math skills
in order: non symbolic number learn count list symbolic number arithmetic operations rational umbers algebra
81
symbolic number mapping
two forms- number words (one) and arabic digits (1)
82
number word acquisition
children learn count sequence by rote (memorising) before understanding meaning learn meaning of number two by 24-36 months culture dependent
83
morphological bootstrapping hypothesis
language with singular and plural distinction help children to learn the meaning of numbers faster
84
counting principles
one-to-one stable order abstraction order irrelevance cardinality
85
one-to-one principle
each object only counted once each number word paired with one object all objects paired with number word
86
stable order principle
number words are recited in a fixed order 1,2,3,4,5
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abstraction principle
any array of sets can be counted regardless of characteristics (shape, colour, size) e.g. can count 3 dogs and 3 cats as 6 animals
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order irrelevance principle
order in which objects are counted doesn't matter leads to the same result
89
cardinality principle
last number in count sequence describes how many there were in total (count to five = five objects) describes order and quantity
90
testing cardinality principle
grabbers - only procedural knowledge pre-number-knowers - number children give isn't related to number asked subset-knowers - numbers too high = unable to grasp cardinal principle knower - successful (usually around 3-4yrs)
91
arabic digit acquisition
actual written digit (e.g 3 ) required later than number words explicitly taught in schools
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jimenez - connecting spoken word to written word
2-4 yrs A - quantity to number word B - number word to quantity C - number word to digit D - digit to number word E - quantity to digit F - digit to quantity
93
connecting number words, digits, quantities
3-4 yrs six mapping tasks mapping between numerals and quantities more difficult than between number words and quantities/numerals
94
ordinality
relation between items in a sequence emerges later than cardinality 7-12 yrs: adjacent (2,1,3) and non adjacent sequences (3,5,8) accurate
95
number order task
choose numbers in order from smallest to largest asap more appropriate for younger children
96
order judgement task
presented with 3 numbers - decide if sequence in ascending order or not asap struggle when order is not adjacent sequence and not in order
97
home numeracy environment
parents involvement no consensus on specific components that should be included to capture parents involvement small positive correlation between one and maths achievement (advanced activities)
98
obersvaetional studies/questionnaires - maths
parent number talk: record parent utterances related to maths language (number words and magnitude comparison) quantify code words home numeracy environment - direct: explicite activities targeting maths indirect: everyday activities coincidentally involving maths
99
HNE and parent factors
most studies involve mothers when both parents participate, only mothers activities linked to children maths skills mothers with higher education = expose children to more advanced numeracy parents attitudes/anxiety towards maths influences children
100
early numeracy skills
large individual differences children who enter kindergarten with poor numeracy don't catch up - lack of early identification meta-analysis: - early maths skills strong predictor on later maths and reading skills + overall academic performance
101
predictors of numeracy
pathways to mathematics model: 3 pathways -quantitative -working memory -linguistic
102
quantitative skills
subitising = determine number of items in set without counting produced maths outcome 2 yrs later non symbolic arithmetic = adding/subtracting with mainpulations counting estimation = estimate dots without counting number comparison = non-symbolic (dots), symbolic (digits) - asked which side has more dots/digits
103
working memory pathway
verbal WM - asked to repeat list of numbers in reverse visuospatial WM - predicted math outcome grade 1/2 yrs later contribute equally
104
linguistic skills pathway
phonological awareness (knowledge of sound structure) and receptive vocabulary (words understood) strongest predictor of maths grades: may be used as baseline test
105
pathways to mathematics
verbal WM visual WM linguistics account for variability in arithmetic (44-79%), word problems (53-61%), number system knowledge (48-64%) and geometry (26-84%)
106
early intervention for maths skills
domain general interventions for WM and linguistic skills not been proven successful training quantitative skills better 60% that struggled w maths in kindergarten continued to have difficulty in grade 5
107
criteria for evaluating early interventions
include children at risk and a comparison group random assignment pretest, intermediate post test and delayed post test
108
developmental dyscalculia
specific impairment of mathematic ability affects 3.5-6.5%
109
effects of DD
difficulties with: number sense - early childhood sorting objects recognising patterns/groups comparing/contrasting magnitude learning numbers and how to count matching numbers with amounts
110
effects of DD - school
difficulty remembering basic maths understanding whats written
111
effects of DD - adults
difficulty with more advanced maths
112
two theories of DD
domain specific - underlying core deficit is a numeral defcitit domain general - impairment in non-numerical mechanisms
113
four criteria - specific learning disorder
A - difficulty learning for 6 months - figures, numbers, calculations b - skills lower than expected for age - interfere with daily living. confirmed using standardised measurements c - difficulties begin during school d not better explained by other factors
114
symptoms of DD
slow to develop basic skills frustration struggle with time poor sense of direction poor LTM difficulty playing strategy games/keeping score
115
DSM-5 of DD
disorder manifested in learning difficulties - lasts for at least 6 months dropped the use of IQ discrepancy criterion (difficulties didn't differ depending on IQ level)
116
comorbidity of developmental dyscalculia and other learning disorders
1/2 to 2/3 comorbid with e.g. ADHD, motor deficits reasons unclear implication = less able to use compensatory mechanisms due to other deficits
117
domain specific: symbolic processing deficit
access deficit - difficulty accessing numerical magnitude representations from symbols longer response time for symbolic comparison (e.g. 5 and 9 - which is more?) smaller/ absent size congruity in DD and make more mistakes - magnitude comparison
118
domains specific: approximate number system deficit
deficit in system responsible for processing numerical magnitude information deficits processing large non symbolic information and magnitude children with maths learning disability had poorer ANS acuity problem: several studies fail to find ANS deficit in children with DD
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domain general: working memory
deficits in visuospatial working memory at behavioural and neural level in DD
120
domain general: attentional/executive deficits
inhibition and shifting impaired in DD
121
mathematics anxiety
anxiety that appears with the manipulation of numbers in ordinary life and academic situations appears with and without general anxiety up to 2/3s of variance might be unexplained by test anxiety can lead to global avoidance may be present form as young as 6 years old
122
diagnosing maths anxiety
no formal diagnosis many people wouldn't meet criteria for normal anxiety
123
measuring maths anxiety
rely on self-report questionnaires mathematics anxiety rating scale - 98 items (adapted to different ages) MARS-A - adults MARS-E -4/6th grade MAQ - 6-9yrs SEMA - 7-10yrs
124
maths anxiety and maths achievement
negative correlation many conflicting studies
125
maths anxiety - deficit theory
consequence of poor performance = maths anxiety
126
maths anxiety - debilitating anxiety model
leads to avoiding maths - depletes cognitive resources anxiety treatment = improved math
127
maths anxiety - reciprocal theory
bidirectional relaitionship Higher anxiety = poor performance; poor performance = higher anxiety
128
maths anxiety and low working memory
lower verbal short term and working memory scores with high maths anxiety lower WM capacity
129
maths anxiety and high working memory
higher cortisol (stress) = poorer performance more negative impact on math anxiety in this with high WM cortisol can have positive effect in those without math anxiety and high WM
130
risk factors for math anxiety
low maths ability and WM genetics environmental reasons e.g teachers, expectations
131
alleviating maths anxiety
systematic desensitisation = gradual exposure while maintaining relaxed state expressive writing, focused breathing maths training