Test 1 Flashcards

(63 cards)

1
Q

What statistical method is used to assess whether or not the number of observed individuals with certain phenotypes are an acceptable fit to an expected Mendelian ratio?

A

chi-square test

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2
Q

maternal inheritance is the dominant mode of inheritance for

A

organelle genes

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3
Q

Syntenic genes can assort independently when

A

They are far apart on a chromosome, and crossing over occurs frequently between the genes.

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4
Q

genetic linkage leads to the production of a significantly greater than expected number of gametes containing chromosomes with

A

parental combinations of alleles

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5
Q

in a dihybrid cross exhibiting complete genetic linkage, what would you expect?

A

two equally frequent gametes containing only parental allele combinations and no recombinant gametes

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6
Q

which progeny phenotypic ratio is expected when a diploid monohybrid is selfed?

A

3:1

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7
Q

which progeny phenotypic ratio is expect in a diploid monohybrid testcross

A

1:1

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8
Q

which progeny phenotypic ratio is expected ina cross between a homozygous dominant and homozygous recessive (diploid)?

A

1:0

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9
Q

what is the phenotypic ratio of a cross between heterozygous dominant and wild-type parents?

A

1:0

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10
Q

sexual reproduction uses _____ to generate ______ gametes, which join at fertilization

A

meiosis; haploid

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11
Q

when a diploid cell divides by mitosis, result is ____

A

identical diploid cells

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12
Q

Mendel performed many types of crosses, including those in which the same genotypes are crossed but the sexes of the parents are switched. These are known as ________.

A

reciprocal crosses

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13
Q

holliday junctions are

A

formed during the process of crossi ng over

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14
Q

one genetic map unit (mu) is the distance between genes for which 1 product of meiosis in ____ is recombinant

A

100

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15
Q

what type of allele is often detected as a distortion in segregation ratios, where one class of expected progeny is missing.

A

lethal allele

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16
Q

Syntenic genes can assort independently when

A

they are far apart on a chromosome and crossing over occurs frequently between the genes.

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17
Q

the alleles of linked genes tend to ____

A

segregate together during gamete production

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18
Q

mitosis

A

1 cell divides into two genetically identical daughter cells (diploid)

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19
Q

meiosis

A

1 cell divides into 4 daughter cells with one gamete from each parent.

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20
Q

blending theory

A

viewed the traits in offspring as a mixture of the parental traits

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21
Q

pure breeding

A

breeding two of the same strains together to produce the same phenotype

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22
Q

crossbreeding

A

allow to observe F1 and F2 traits

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23
Q

reciprocal crosses

A

made when the same crossses are made but from different sexes

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24
Q

test crosses

A

are made when a plant is crossed with the recessive pure breeding parent

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25
AA
homozygous dominant
26
Aa
heterozygous dominat
27
aa
recessive homozygous
28
autosomal dominant inheritance
have one affected parent, both males and females are affected; traits are expressed in each generation.
29
autosomal recessive inheritance
The affected individual has no affected parents.traits can skip generations
30
chromosomal sex
the presence of sex chromosomes associated with males and females
31
phenotypic sex
the internal and external morphology found in each sex
32
XX
female
33
XY
male
34
law of independent assortment
during the formation of gametes segregation of alleles at one locus is independent of alleles at another locus
35
reject null hypothesis
p>0.05
36
recombination happens in
prophase 1 and meiosis 1
37
sythenic genes
genes located on teh same chromosome
38
linked genes
alleles so close together they cannot sort independently
39
parent no recombinantion
1-r
40
recombination
r
41
incomplete penetrance
when traits are occasionally nonpenetant
42
variable expressivity
the same genotype produces a range of phenotypes that vary in degree
43
gene-environment interactions
when the environment influences the phenotype that perhaps explains incomplete penetrance and variable exoressivity in some instance
44
epistasis
gene interaction where alleles at one gene influence the function of alleles at another gene.
45
same complementation group
mutations that do not complement each other
46
feature sthat make bacteria useful to genticist
genome simplicity, uncomplicated genotypes, rappid generation time, large number of progeny, ease of propagation, numerous heritable differences
47
conjugation
the transfer of replicated DNA from a doner to a recipient
48
transformation
the uptake of DNA from the environment. It is a four step process that is preceded by lysis.
49
transduction
the transfer of DNA from one bacterium to another by a viral vector.
50
Fertility plasmid
contains genes that promote its own transfer from donors to recipients
51
Resistance plasmid
caries antibiotic resistance genes that can be transferred to recipient cells
52
prototrophic
WT, complete medium, minimum medium
53
auxotrophic
mutant, complete medium
54
haploinsufficient
one copy of the allele is not enough for wild-type phenotype
55
Lysis
The breakage of a donor cell and fragmentation of the DNA of the donor
56
Cotransformation
Happens when genes are close together
57
Bacteriophage
Viruses (eater of bacteria), infection and parasitize bacteria.
58
a bacterium that is unable to grow on minimal medium is said to be
auxotrophic
59
Joshua Lederberg and Edward Tatum discovered a sex-like process in bacteria using
population of cells with complementing auxotrophs, and the measurement of the generation of prototrophs during microbial mixing
60
Bernard Davis tested the "cross-feeding" interpretation of some data that showed the phenotype of one microbe as capable of being changed by another microbe. His contribution can be summarized as
placing a barrier between bacterial strains with complementing auxotrophs to assess whether contact between cells was required for genetic exchange.
61
An F+ microbial strain would best be described as
a bacterium with a plasmid that confers mating competency (or fertility)
62
An Hfr microbial strain would best be described as
a bacterium is containing a chromosomally integrated plasmid conferring mating competency.
63
what allows the compilation of time-of-entry maps?
the fact that gene entry can proceed in either direction