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drugs and behaviour > Test 1 > Flashcards

Test 1 Flashcards

1
Q

What is antabuse?

A

Competes with acetylaldehyde for AD

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2
Q

What is alcohol dehydrogenase?

A

Catalyzes the oxidation of secondary and primary alcohols.

The more AD present, the higher tolerance

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3
Q

What is Kidney Nephrons?

A

Bowmans capsule —>

Glomerulus —>

     Urinary bladder
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4
Q

What is the pH of a solution?

A

A measure of the hydrogen ions

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5
Q

Define patency

A

The amount of drug you need to get the desired effect

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6
Q

What is antagonism?

A

When one drugs diminishes the effect of another

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7
Q

Speed effectiveness of 4 parental drugs

A

I.V. > I.P. > I.M. > S.C.

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8
Q

What is the super additive effect?

A

Combing drug effectiveness

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9
Q

What does a low ED50 mean?

A

The drug is more potent

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10
Q

What is an example of a conditioned response in the paw-lick test?

A

Tolerance

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11
Q

Define latency

A

Delay

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12
Q

What does MED50 mean

A

Median effective dose (when 50% of the drug users are effected)

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13
Q

What are 4 way of drug administration?

A

Parental, Oral, Transdermal, and Inhilation

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14
Q

What does an MLD50 mean?

A

Median Lethal Dose (the dose at which 50% of drug participants died)

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15
Q

What are the 4 types of parenteral administration?

A

Intravenous, intramuscular, subcutaneous, and interperitionel

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16
Q

What is the force of diffusion?

A

Moving from a high concentration to a low concentration

17
Q

What are the 4 kinds of ions in MP

A

Na+ ions, K+ ions, Cl- ions, and proteins

18
Q

What is an example of a Unconditioned Stimulus in the paw-lick latency test

A

The drug (morphine)

19
Q

What will happen if you give an injection in the white room with NO morphine

A

After tolerance develops in a white room, the rats becomes hyperalges (more sensitive to pain). They have an extremely short latency (delays) to lick their paws.

20
Q

Give an example of a unconditioned response in the paw-lick latency test.

A

Increasing the latency (delay) to lick their paws

21
Q

Give an example of a conditioned stimulus in the paw-lick latency test.

A

The white room (triggers tolerance)

22
Q

What is a GABA neurotransmitter?

A

It is a universal inhibitory neurotransmitter

23
Q

What are forces that maintain the resting potential in neurons?

A

The Na+ and K+ pump and selective permeability

24
Q

What is the resting potential of a neuron?

A

Diffusion and electrostatic pressure

25
Q

How do neurons communicate?

A

Through the action potential where both the inside and the outside of the cell is 70 MV and the neuron is polarized

26
Q

Define angonist

A

To enhance

27
Q

Define antagonist

A

To weaken

drugs and behaviour (2 decks)

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