Test #1: Muscle Physiology & Muscle Actions of the Lower Extremity Flashcards
(159 cards)
What is a by-product of Glucose metabolism?
ATP (adenosine triphosphate)
Where is ATP stored?
Skeletal muscle
How much and for what purpose is ATP stored in skeletal muscle?
Small amounts to initiate contraction.
How many seconds does this initial amount of ATP fuel activity?
About 6 seconds
Once the initial small amount of ATP is depleted, what must occur for muscle contraction to continue?
New supplies of ATP must be regenerated
What is a secondary source of energy in skeletal muscle after the 6 seconds of ATP is depleted?
Creatine Phosphate (CP)
How many seconds does Creatine Phosphate fuel activity?
About 20 seconds
Once the Creatine Phosphate is depleted, what must occur for muscle contraction to continue?
More energy must be generated
How many pathways for generating energy for skeletal muscle?
2 pathways
What are 2 pathways for energy to be generated for skeletal muscle?
- Aerobic respiration; and 2. Anaerobic respiration
Aerobic Respiration
a. Requires O2
b. In Mitochondria
c. Is a slow process
d. High yield of ATP (36 molecules)
e. No lactic acid
f. Glucose + O2 > CO2, H20 + 36 ATP
Anearobic Respiration
a. Does not require O2
b. In Cytosol
c. Is a fast process
d. Low yield of ATP (2 molecules)
e. Lactic acid is a by-product
f. Glucose > Pyruvic Acid + 2 ATP; Pyruvic Acid > Lactic Acid + H+
How quickly is lactic acid reused within the body?
30-60 minutes after activity
Liver (converts back to glycogen)
Heart or Kidneys (uses as fuel)
Sweat it out
During activity, what is the cause of muscle burn?
Lactic acid and hydrogen ions (H+) from anaerobic respiration.
What is muscle pain the day after an activity?
Delayed Onset Muscle Soreness (DOMS)
How long after an activity for DOMS?
12-24 hours
What is the cause of DOMS?
Microtears in connective tissue or muscle tissue.
What is muscle fatigue?
Occurs when a muscle is no longer able to contract even though it’s stimulated to do so.
How many causes for muscle fatigue?
3 causes
What are the 3 causes for muscle fatigue?
- Lack of oxygen; 2. Change in Ph; and 3. Electrolyte Imbalance
Muscle Fatigue: Lack of O2
A lack of O2 forces the use of anaerobic pathway which builds lactic acid.
Muscle Fatigue: Change in Ph
Lactic acid gives off Hydrogen ions (H+); this greatly lowers Ph which irritates muscle physiology.
Muscle Fatigue: Electrolyte Imbalance
Sodium (Na), Potassium (K) and Calcium (Ca) need to be in proper balance or muscles cannot contract.
Muscle Contraction: All or none principal
When a skeletal muscle cell is stimulated to contract it contracts fully or not at all.