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Flashcards in Test 2 Deck (39)
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1

Hematologic syndrome stages

Dose of 200-1000 rads
Prodromal stage
Latent period
Manifest stage

2

Prodromal stage

Dose of 100 rads or more to whole body, symptoms within mins nausea , vomiting, diarrhea, reduction of WBC

3

Latent period

No visible signs of radiation illness.. Length depends on dose (hr to weeks) smaller the dose the longer the latent period

4

Manifest illness stage

Symptoms vomiting, mild diarrhea.malaise, lethargy, and fever ...depending on dose depends on recovery or death.

5

Gastrointestinal syndrome

Dose of 1000-5000 rads
Prodromal- vomiting diarrhea hrs
Latent 3-5 days
Manifest nausea vomiting diarrhea
Death 4-10 days

6

Cns syndrome

5000 rads
Death within hours to days
Nausea and diarrhea within mins
Confusing burning of skin loss of vision 6-12 latent period
Death always outcome

7

Ld50/30

Whole body exposure will result in 50% of death within 30 days of exposure

8

Ld#

Lethal dose of the % of pop.

9

Mean survival time

Average time between exposure and death

10

Limited body exposure compared to local tissue exposure

This means 10rads is worst to whole body compared to just to the stomach

11

% of skin replaced everyday

2%

12

What % of intentional lining is replaced everyday

50%

13

Erythema

Skin redding

14

Desquamation

Removal of protective layer of skin

15

Moist desquamation

With higher doses and is known the clinical tolerance for protective layer

16

SED50

(Skin erythema dose) is the dose required to affect 50% of persons so irradiated SED50 is = to 600 rads or 6 Gy

17

Temporary sterility

200rads

18

Permanent sterility

500rads

19

Damage from radiation on the 3 levels

Molecular cellular and organic

20

Where indirect hits And what is causes

Free radicals and water molecule are damaged

21

3 main damages from irradiation of DNA

Main chain scission- the break in long chains
Cross linking- spurlike extensions off main
Point lesions- areas on molecules are damaged bc radiation

22

Usually the result of point lesion

Cell damages from low does of radiation

23

Photons striking a cells master molecule DNA

Results in death

24

Somatic effect of radiation called erythema from large dose of radiation

Like a sunburn

25

Ld50/60

Whole body 350 rads 50% of ppl will die in 60days

26

Most radiation resistant

S phase

27

Most radiation sensitive

Mitosis

28

Direct hits of body tissues and cell from _____ particles

Alpha

29

Best example of organic damage from radiation

Leukemia

30

Diagnostic to pt getting a gi with 4 mins of fluoro

Time should show no early or late effects