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Biomedical Physiology > Test 2 Drugs > Flashcards

Test 2 Drugs Flashcards

(55 cards)

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0
Q

prozac

A

SSRI- selective serotonin re-uptake inhibitor
causes serotonin to last longer in the synapse
used to treat depression

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1
Q

dopamine

A

is a catecholamine

secreted by limbic system neurons- enhances reward, drive, and motivation

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2
Q

norepinephrine

A

a catecholamine

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3
Q

epinephrine

A

a catecholamine

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4
Q

sertonin

A

(5-HT)

indolamine

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5
Q

histamines

A

in posterior hypothalamus
important in modulation of sleep
controls which memories and learning are forgotten

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6
Q

glutamate, aspartate

A

excitatory amino acid derivatives

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7
Q

angel dust

A

PSP

amino acid derivative that binds well to glutamate receptors

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8
Q

GABA

A

inhibitory NT

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9
Q

benzodiazapines

A

anti- anxiety drug

enhances GABA production to activate gabanergic neurons- causes an overall calming effect

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10
Q

Glycine

A

inhibitory NT that effects Cl- channels to hyperpolarize the neuron so it is less likely to respond to stimulus

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11
Q

strychnine

A

a poison
is an antagonist of glycine- glycine receptor blocker
causes too much stimulation

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12
Q

substance P

A

found in nocioceptors (transmit pain)

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13
Q

capsaicin

A

can bind to TRPV1 protein on pain and heat sensing neurons

can deplete substance P and cause temporary relief from pain

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14
Q

opioids

A

cause sense of euphoria/well-being

in limbic system

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15
Q

endophins

A

opioid

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16
Q

enkaphalius

A

opioid

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17
Q

dynorphins

A

opiod

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18
Q

opium

A

bind opioid receptors and cause euphoria

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19
Q

morphine

A

binds opioid receptors= euphoria

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20
Q

nitric oxide

A

excitatory in CNS

in PNS it is a potent relaxer of endothelial walls

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21
Q

viagra

A

increases nitric oxide levels to relax blood vessels going to penis
treats erectile dysfunction

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22
Q

resperine=serpasil

Study These Flashcards
A

blocks uptake of NE into synaptic vesicles so it is exposed to MAO in the cytoplasm that breaks it down
leads to decrease in sympathetic activity

23
Q

albuterol

Study These Flashcards
A

epinephrine mimic that binds to B2 receptors to open airways

24
asthma medication
B2 agonist or M1/M3 inhibitor
25
neosynephrine (claritin)
decongestant active ingredient is pseudoephedrine potent a1 receptor stimulator agonist causes vasoconstriction of the vessels supplying blood to the glands---therefore decrease their ability to secrete
26
pilocarpine
mimics the effect of Ach but not detected by acetylcholinesterase so ach stays in the synapse longer used to treat glaucoma- N and M receptor agaonist- increase in ciliary muscle contraction
27
Duvoid
M receptor stimulator used to treat non-obstructive urinary retension increase contraction of detrussor muscle, decrease in sphincter muscle contraction
28
nicorete/ nicoderm
N receptor agaonist has biphasic action ~low dose stimulate N1 and N2 ~high dose inhibits N1 and N2
29
trimethaphan (arfonad)
N1 receptor antagonist (blocker) used during anesthesia to produce controlled hypotension blocks autonomic input
30
atropine
aka belladonna M receptor blocker used to make pupils dialate from deadly nightshade flower
31
mydriacyl
M receptor blocker | what is now used to dialate eyes b/c it doesn't last as long as atropine
32
detrol
M receptor blocker | used to treat bladder instability or incontinence
33
bentyl
M receptor blocker used to treat IBS by decreasing gut motility
34
scopolamine (hyoscine)
derivative of deadly nightshade | used to put women in twilight sleep during childbirth
35
Demsec
drug that blocks synthesis of NE/E by blocking tyrosine hydrozylase that converts L-tyrosine to L-dopa decreases the sympathetic effect was once used to treat hypertension by reducing NE/E
36
methyl-dopa (aldomet)
false NT (instead of L-dopa) gets converted to alpha methyl norepinephrine and released in synapse but does not bind to a1 or B1 receptors acts as though there is no NT it DOES bind a2 receptors in axonal terminal and shuts down stimulation of sympathetic used to treat hypertension
37
ismelin
blocks release of NE/E | used to treat hypertension
38
serpasil (reserpine)
blocks transport of NE back into synaptic vesicles (uptake 1) so it increases amount of time MAO can breakdown NE
39
Dextrine
synergizes and makes NE/E bind better (false displacement) | used to treat hypertension and narcolepsy
40
epi-pen
epinephrine mostly binds to a1 receptors and promote sympathetic effects increase blood pressure and treat shock
41
levophed (norepinephrine)
binds a1, a2 B1, B2 receptors | used to treat hypotension and increase blood pressure
42
phenylephrin (pseudoephrine)
synthetic NE/E- is the active ingredient in nasal decongestants bind a1 of smooth muscles around vessels going to nasolacrimal glands and increases vasoconstriction stops runny nose but incresases blood pressure
43
clonidine (catapress)
a2 agonist | used to treat hypertension, increases vasodilation, decreases blood pressure
44
isuprel (isoproternol)
binds both B1 and B2 used to treat shock increases cardiac output and blood pressure
45
dubotrex
B1 specific agonist | increase heart rate and strength of contraction and cardiac output
46
proventil (maxair)
B2 specific agonist used to treat asthma will also impair B2 receptors in the GI tract
47
Yupotar
B2 specific agaonist | used to delay labor by decreasing uterine contractions
48
prazosin (minipress)
block a receptors on smooth muscle cells around arteries so decrease blood pressure used to treat hypertension
49
indreal (propranolol)
blocks B1 and B2 used to treat hypertension decrease HR and blood pressure
50
lopressor tenormin toprol-XL
B1 specific blockers for hypertension
51
coreg
B1, B2, and a1 blocker | decreases blood pressure
52
hytrin
block a receptors on smooth muscle cells around arteries so decrease blood pressure used to treat hypertension
53
flomax
block a receptors on smooth muscle cells around arteries so decrease blood pressure used to treat hypertension for those with enlarged prostate, used to block sympathetic effects that block urination
54
Cardura
block a receptors on smooth muscle cells around arteries so decrease blood pressure used to treat hypertension for those with enlarged prostate, blocks sympathetic effects to allow urination

Biomedical Physiology (3 decks)

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