test 2 GP Flashcards

1
Q

General Anesthesia - how long ago was it introduced? what do we know?

A

General Anesthesia was introduced approximately 150 years ago!

Despite more than 100 years of active research – the molecular mechanisms responsible remains an Unsolved Mystery!

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2
Q

3 major reasons that anesthetic drugs are difficult to study

A

Anesthesia is defined: a change in responses of an “intact animal” to external stimuli- link between observed anesthetic state and the state defined in vivo= very difficult
A wide variety of structurally unrelated compounds can produce clinical anesthesia= suggests multiple molecular mechanisms that can produce clinical anesthesia
Anesthetics work at very high concentrations in comparison to drugs; this implies that they have a very low affinity to the receptor and do not stay bound for long= this makes it much more difficult to observe and characterize than high affinity bonding

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3
Q

What is Anesthesia?

A
  • A collection of “component” changes in behavior or perception
  • The components of anesthetic state: unconsciousness, amnesia, analgesia, immobility, and attenuation of autonomic responses to noxious stimuli
  • Difficulty defining anesthesia as our understanding of the mechanisms of consciousness is amorphous at the present (work continuing to be done)
  • New physiologic markers used to define consciousness being studied
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4
Q

How is anesthesia measured?

A
  • Quantitative measures of anesthetic potency must be measured
  • Minimum alveolar concentration (MAC) = partial pressure of gas at which 50% of humans do not respond to surgical stimulation
  • MAC = Dose: Represents the average response of the whole of the population/ not the response of a single subject
  • End-tidal concentration of gas- provides an index of the “free” concentration of drug required to produce anesthesia; since the end-tidal gas concentration is in equilibrium with the free plasma concentration and BIS monitoring
  • MAC only refers to the concentration of agent. NOT the amount of other adjuncts that we have given
  • BIS monitoring has also become a standard of care
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5
Q

Meyer- Overton Rule:

A
  • More than 100yrs ago Meyer and Overton observed that the potency of gases as anesthetics was strongly correlated with their solubility in olive oil- this idea is referred to as: The unitary theory of anesthesia
  • There is a linear relationship between the oil/gas partition coefficient and anesthetic potency (MAC)- theories regarding protein binding also satisfy the Meyer-Overton Rule
  • Anesthetic agents must disrupt the function of neurons mediating behavior, consciousness & memory
  • Anesthesia alters neuronal communication by:
  • altering neuronal excitability- create a more negative rmp= hyperpolarize the neuron which decreases the action potential
  • synaptic transmission- widely considered to be the most likely subcellular site of general anesthetic action
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6
Q

Unitary theory

A

thinking most drugs act same way… but we know there is not one single way so kind of disproven…

Newer research showing more action at the synapses

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7
Q

GABA activated ION Channels:

A
  • Many anesthetics potentiate GABA in CNS
  • GABA receptors are probable targets (other- glycine, neuronal nicotinic & 5HT3)
  • Relevant targets for Amidate & Propofol
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8
Q

Where in the CNS do Anesthetics work?

A
  • Suppress circuits in the spinal cord & brainstem
  • Induce immobility & disrupt autonomic homeostasis

no single site does anesthesia

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9
Q

What we know about anesthesia

A

Anesthetics have powerful and widespread effects on synaptic transmition

Volatile anesthetics directly reduce excitatory synaptic transmission of spinal neurons

Propofol depresses activity in ventral horn neurons via GABAergic mechanism

Isoflurane suppresses interneurons of central pattern generators involved in coordinated movements

Anesthetics can alter descending, afferent, efferent & modulating limbs of reflex arcs for reacting to noxious stimulation

It is clear that all anesthetic acctions cannot be localized to a specific site in the CNS – much evidence allows that different components of the anesthetic state are mediated by actions of disparate anatomic sites

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10
Q

Autonomic Control:

A
  • Anesthetics exert profound effects on cardiopulmonary & thermoregulatory homeostatic circuitry without autonomic centers in the brainstem & hypothalamus
  • Inspiratory neurons in the medulla drive phrenic motor neurons to activate diaphragmatic contraction
  • Halothane suppresses the spontaneous activity of these neurons
  • Anesthetics also have an effect on the cardiovascular reflexes mediated by nuclei in the brainstem
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11
Q

AMNESIA

A

the hippocampus is a plausible target for suppression of memory formation

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12
Q

RETICULAR ACTIVATING SYSTEM (RAS)

A

Is a diffuse collection of brainstem neurons that mediate arousal

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13
Q

CEREBRAL CORTEX

A
  • Is the major site for generating awareness of the external environment; primary sensory areas
  • Disruption feedback by anesthetics may contribute to impaired consciousness
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14
Q

****Extubating Criteria****

A
  • EXTUBATION OF THE TRACHEA MUST NOT BE CONSIDERED A BENIGN PROCEDURE
  • Oropharynx/ hypopharynx cleared of secretions
  • 5 second head lift; sustained hand grasp
  • Adequate pain control
  • Minimal end expiratory concentration of inhaled agent
  • Vital capacity > or = 10ml/kg
  • Negative inspiratory pressure > 20cm H2O
  • Tidal volume >6cc/kgSustained tetany
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15
Q

Report to PACU

A

Greet RN
Offer patients name
Give procedure while hooking up the O2
Put the pulse ox on first
Attach BP cuff and cycle
Put EKG leads on

List antibiotics given
Amount of narcotic
Patient allergies
Any reactions to meds
Any issues with airway or extubating
Make sure the RN is comfortable with patient and report before you leave

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16
Q

Maintenance of LMA General:

A

Get the patient back breathing
Assist when necessary
Let surgeon know that the patient is ready for injection of local
Have propofol ready in case patient moves with the stimulation
Watch over the drapes and make sure that all is well
The Goal is to have patient breathing throughout with little to no support
No vent; no PSV on vent- learn the right way(Is allowable to use PSV-pro setting with LMA- I am just “old school” Follow the K.I.S.S. plan
Depth of anesthesia matters so they don’t get too light or too deep- it’s a nice way to give anesthesia in this situation
I use the patient’s respiratory rate to guide my narcotic administration

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17
Q

Emergence from LMA General:

A

The patient in this case will likely have a nice local block from the orthopod (Orthopedic Surgeon)
Pain isn’t going to be a big issue
Watch over the drapes because tourniquet tolerance is going to be the only thing that will cause discomfort at the end
Back off on gas and perhaps run 70% nitrous oxide (N2O)
If respiratory rate picks up- It’s ok to work in narcotic
As the dressing is going on- 100% FiO2
Increase your flow rate
Untape eyes
Let patient blow off all gas
Reasonable criteria for LMA removal is when the patient is awake- stay out of trouble
LMA is not stimulating, painful or gag inducing
REMEMBER: 2 types of CRNA …..

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18
Q

LMA Removal:

A

Patient opens eyes you pull out the LMA
I put nasal cannula on the patient
Lift the head of the stretcher and ask if they are comfortable and let patient know that everything went well.
Head to PACU (Post Anesthesia Care Unit)

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19
Q

American Society of Anesthesiologists (ASA)

A

Designed a classification system used to define relative risk prior to conscious sedation and surgical anesthesia
There are many other risk assessments available
This one has shown to be the greatest predictor of perioperative risk
Is the most widely used tool

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20
Q

ASA Physical Status Classification of Patients:

A

Class 1: Normal healthy patient
Class 2: Patient with mild systemic disease (no functional limitations)
Class 3: Patient with severe systemic disease (some functional limitations)
Class 4: Patient with severe systemic disease that is a constant threat to life (functionally incapacitated)
Class 5: Moribund patient who is not expected to survive without the operation
Class 6: Brain-dead patient whose organs are being removed for donor purpose
E: If the procedure is an emergency the physical status is followed by an “E”

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21
Q

NPO

A

nothing per ora; (not allowed to orally consume)

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22
Q

PO

A

per ora; (something ingested orally)

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23
Q

Qd

A

each day

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24
Q

BID

A

twice per day

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25
TID
Three times per day
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QID
Four times per day
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Q6h Q8h
Q6h- Every six hours Q8h- Every eight hours
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SAB
Subarachnoid block (this is a spinal)
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LMA
LMA- Laryngeal mask airway
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OET
OET- Oral endotracheal tube
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NET
NET- Nasal endotracheal tube
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GETA
GETA- General endotracheal anesthetic
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TIVA
TIVA- Total Intravenous Anesthetic
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MAC
MAC- Monitored anesthesia care (not to be confused with minimum alveolar concentration)
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LOC
LOC- Level of consciousness
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MAP
MAP- Mean arterial pressure
37
CSF
CSF- Cerebral spinal fluid
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PAW
PAW- peak airway pressure
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CPAP
CPAP- Continuous positive pressure ventilation
40
EBL
EBL- Estimated blood loss
41
IVGA
IVGA- Intravenous general anesthesia
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PEEP
PEEP- Positive end expiratory pressure
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Intrathecal
Intrathecal- inside the dura
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Epidural
Epidural- outside of the dura, In the epidural space (which is a potential space)
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O's
Oxygen slang
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Gas
Gas- commonly the way an anesthesia provider refers to volatile anesthetic agents
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GCS
GCS- Glasgcow coma scale
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HOB
HOB- Head of bed
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CVA
CVA- cerebral vascular accident (stroke)
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MVA
MVA- Motor vehicle accident
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GSW
GSW- Gun shot wound
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OB
OB- refers to obstetrics (usually the unit itself)
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ED/ER
ED/ER- refers to the emergency department/ emergency room (depending upon your age)
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PACU
PACU- Post anesthesia care unit
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Pre-op
Pre-op- Preoperative area
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Vt
Vt- Tidal volume
57
BBSE
BBSE- Bilateral breath sounds equal (a fast way to chart lung sounds that are clear
58
IOP
IOP- Intraocular pressure
59
ICP
ICP- intracranial pressure
60
CABG
CABG- Coronary artery bypass graft (this patient has had CABG- pronounced cabbage)
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CBF
CBF- Cerebral blood flow
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CMR
CMR- Cerebral metabolic rate
63
MDA
MDA- Slang term for anesthesiologists, depending on the Doctor they may find this offensive. No other clinical specialty is defined this way and what if they are a D.O.? Will you refer to them as a DOA?? (please don’t) So understand to whom someone is referring but call them anesthesiologist. If you cannot say that word you are in the wrong field.
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•**Good pre-op evaluation:**
Can reduce cost of surgery Can reduce cancellation rates Increase resource utilization in the OR (Why do we care?)
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Components required in a Pre-op Eval:
Review of the medical record History and physical (pertinent to the surgery) Appropriate diagnostic tests Appropriate pre-op consultations Determine whether the patient’s condition can be improved prior to surgery Answer all questions Obtain informed consent
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Challenges to preop assessment
Pt having outpatient same day Fast turn over Limited time to get to know pt Limited time to create relationship Limited time to engender trust Limited time to answer questions
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three categories used in forms to rate?
Forms are Rated using 3 Categories: Informational Content Ease of Use Ease of Reading
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Classification of Urgency of Surgical Procedures
EMERGENCY- Life, Limb or Organ Saving; surgery \<6hours- examples: ruptured aortic aneurysm; major trauma to thorax or abdomen; acute increase in ICP URGENT- Conditions threaten life, limb or organ; surgery within 6-12 hours- examples: perforated bowel; compound fracture; eye injury TIME SENSITIVE- Stable but requires intervention; surgery within days-weeks- examples: tendon; nerve injuries; cancer ELECTIVE- Procedure planned at patient or surgeon convenience; surgery within 1 year- examples: all other procedures that can be planned in advance
69
Urgency Classifications:
Urgency of surgery must be weighed against the optimization of the patient Consider the implications of urgency (i.e. Bowel obstruction- Increased risk of aspiration = RSI) Planned procedures: (Carotid) may require neuro exam & cardiac workup/clearance Positioning & Necessity of blood products: Can surgery be delayed for optimization or will delay increase morbidity?
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Quick Overview of Each System: Barash p. 587
Dx & Procedure: Anesthetic/surgical Hx; MH/Adverse Rxn; Airway difficulties Airway: Known difficulty airway; Sleep Apnea; Teeth; Mallampati; Mouth opening; Chin length; Neck size & Mobility CNS: Seizures; CVA; Syncope; ICP; Mental status; H/A; Weakness; Spinal cord injury; Psych disorder Infectious: COVID; HIV; VRE; Flu; TB; Foreign travel Age/Gender/Height/Weight: Allergies; reactions; Medications (over the counter/herbals and illicit drugs) CV: Congenital disease; HTN; CAD; CHF; Cardiomyopathy; Valvular disorders; Syncope; Arrythmia; Pacer; PVD; Angina; Dyspnea; Orthopnea; Exercise tolerance GI/Hepatic: Liver disease; Hepatitis; N&V; GERD; Bowel obstruction; EtOH use Renal: Insufficiency; Failure; Dialysis Hematology: Anemia; Coagulopathy; Sickle cell; Chemo; Transfusion Hx Vital Signs: NPO status; IV access; Invasive monitoring; Advanced directives Pulmonary: URI/Bronchitis; Pneumonia; Smoking; Asthma; COPD; Cough; dyspnea; Sleep apnea; O2/Inhaler/Steroid use; Pneumothorax; Vent settings; Tube size/depth Endocrine/Metabolic: DM; Thyroid disease; rheumatoid arthritis; steroid use Other: Pregnancy; Weeks of gestation; Trauma Hx
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PONV? risk?
Positive Risk Factors: Female; Hx of PONV or motion sickness; non-smoker; age\<50yrs; General vs Regional; Volatile agents; Nitrous Oxide; Post-operative opioids; Duration of anesthesia; Type of surgery (chole; laparoscopic; Gyn) Conflicting Data: ASA; Menstrual cycle; Anesthesia provider experience; Muscle relaxant reversal Apfel Risk Score: No risk factors= 10% chance of PONV; 1 risk factor= 20%; 2 risk factors= 40%; 3 risk factors= 60%; 4 risk factors= 80%
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OTC Meds
Ephedra: (wt. loss) Tachycardia; HTN; increased sympathomimetic effects with others (arrythmia with digoxin and HTN with oxytocin) Feverfew: (migraines) PLT inhibitor; Increased breathing risk; rebound H/A with cessation GBL; BD; & GHB (body building/ wt. loss) Illegal; death; seizures; severe bradycardia; unconsciousness Garlic: (antioxidant/lowers cholesterol) decreased PLT aggregation Ginger: (anti-nausea) Potent inhibitor of thromboxane synthetase; Increased bleeding time Gingko: (blood thinner) Increased bleeding in pts on anti-coags Ginseng: (energy/ antioxidant) Inhibits PLT aggregation Goldenseal: (laxative/diuretic) Oxytocic= worsens edema & HTN Kavakava: (Anxiolytic) potentiates sedatives & hepatotoxicity Licorice: (Tx of gastric ulcers) HTN; Hypokalemia & edema St John’s Wort (depression/anxiety) prolongs anesthetic effects Valerian: (anxiolytic/sedative) potentiates sedative effects of anesthesia Vitamin E: (slows aging) Increases bleeding in conjunction with anti-coagulants & anti-thrombin meds
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Estimated Energy Requirements for Various Activities
1 MET: Daily self-care; eat; dress; walk indoors; walk a block or 2 on ground level 2-3mph 4METs: Climb a flight of stairs or walk up a hill; walk on ground level 4mph; run a short distance; heavy work around the house; participate in moderate activities (golf, bowling, dancing, doubles tennis) \>10METs: Participate in strenuous sports like swimming; singles tennis; football; basketball or skiing Exercise tolerance remains one of the MOST important predictors of Peri-op risk for non-cardiac surgery; also helps define the need for further testing
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MOST important predictors of Peri-op risk for non-cardiac surgery; also helps define the need for further testing?
Excellent **exercise tolerance** (even in patients with stable angina) suggests that the myocardium can be stressed without failing
75
Indications for Further Cardiac Testing
Based on an algorithm that integrates clinical hx; surgery specific risk & exercise tolerance Evaluate the urgency of surgery & appropriateness of formal pre-evaluation Determine if the pt. has undergone a recent revascularization or CV work up
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Using the Systems Approach: Airway
AIRWAY- Evaluate the oral cavity Evaluate dentition Thyromental Distance Assess neck size, tracheal deviation or masses Ability of the patient to flex and extend the neck and head Evaluation of trauma patients, patients with severe rheumatoid arthritis or Down’s syndrome requires thorough C-spine eval. The presence of symptoms of cord compression may require X-ray exam Modified Mallampati Airway Classification: 1- Full view of soft palate, uvula, tonsillar pillars 2- Soft palate and upper portion of uvula 3- Soft palate 4- Hard palate only
77
Using the Systems Approach: LUNGS-
LUNGS- History of tobacco use Dyspnea Exercise tolerance Recent upper respiratory infection Stridor Snoring Sleep Apnea Physical exam: Respiratory rate; chest excursion; use of accessory muscles; nail color; decreased breath sounds; wheezing; stridor; crackles History of asthma Last time use of a rescue inhaler Last asthma attack
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Using the Systems Approach: CARDIOVASCULAR-
Look for s/sx of uncontrolled hypertension and unstable cardiac disease (MI, CHF, Valvular disease; arrhythmia) Dyspnea Chest pain Syncope Racing rhythms Irregular beats Palpitations SOB Trouble going up and down a flight of stairs Presence of unstable angina = High perioperative risk of MI Periop period= catecholamine surges; hypercoagulable state therefore exacerbates underlying issues such as angina leading to MI Take BP Listen to the heart for murmur radiating to the carotids= aortic stenosis Abnormal rhythm or gallop= heart failure Presence of Bruits over the carotid= needs further work up for stroke risk M.A.C.E- Major adverse cardiac events Low risk procedure= \<1% risk of MACE High risk procedure= \>1% risk of MACE Advanced age = increased risk of MACE and ischemic stroke Hx of CV disease; DM; Cerebrovascular disease= Elevated risk of MACE The goal is to identify clinical risk and need of pre-op cardiac testing The Revised Cardiac Risk Index (RCRI)- assigns peri-op risk using clinical variables The Revised Cardiac Risk Index (RCRI)- High-risk type of surgery History of Ischemic Heart Disease History of Congestive Heart Failure History of Cerebrovascular Disease Pre-operative treatment with Insulin Pre-operative Serum Creatinine (\>2mg/dL) \*Cardiac complications increase with increased risk factors\* Clinical evidence of heart failure: Dyspnea Limited exercise tolerance Orthopnea JVD Crackles Third heart sound Peripheral edema Diabetes associated with CV disease: Diabetes accelerates atherosclerotic disease Diabetics have a higher incidence of silent MI and myocardial ischemia Diabetes requiring insulin for treatment is a risk factor in the RCRI The pre-op ECG should be evaluated for presence of Q-waves Hypertensive disease: Hypertension is associated with increased incidence of silent MI Aggressive treatment of BP is associated with reduction in long-term MI risk Treat SBP \> 150mmHg Treat DBP \> 90mmHg (in pts 60yrs old or \>) \* Elective surgery should be delayed for DBP \>110mmHg\*
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Importance of Surgical Procedure: cardio
Peripheral procedures are associated with extremely low incidence of morbidity and mortality Major open vascular procedures are associated with the highest incidence of complications High risk procedures: major vascular; abdominal; thoracic and orthopedic surgeries
80
cardiovascular importance of exercise tolerance
One of the most important predictors of perioperative risk for non-cardiac surgery (helps define the need for further testing and invasive monitoring) Patients with good exercise tolerance that have stable angina suggests that the myocardium can be stressed without failing Patients with dyspnea associated with chest pain during minimal exertion= extensive CAD and greater perioperative risk
81
Cardiovascular Patients with Coronary Artery Stents:
Early surgery after stent placement = adverse cardiac events (incidence of periop death and hemorrhage) Delay of non-cardiac surgery for 14 days after balloon angioplasty Delay of non-cardiac surgery for 30 days after bare metal stent placement Delay of non-cardiac surgery after drug eluding stents = 12 months
82
CARDIOVASCULAR- Patients with AICDs:
These devices can be impaired by electromagnetic interference (Bovie) during surgery Review the guidelines for AICDs, pacers and arrhythmia monitors
83
\*\*\*\*CARDIOVASCULAR- Risk of re-infarction under general anesthesia after previous MI:\*\*\*\*\*
MI within 3 months or less = 30% incidence MI within 3-6 months = 15% incidence MI greater than 6 months = 6% incidence \*IF re-infarction occurs, the mortality rate is 50%!\*
84
Presence of pulmonary complications
Post-operative pulmonary complications occur more frequently than cardiac in patients having non-cardiac surgery! Complications include: Atelectasis; pneumonia; exacerbation of COPD; pulmonary edema and respiratory failure requiring post-op ventilation \*POST-OP RESPIRATORY FAILURE = MAJOR CAUSE OF M&M\*
85
Pulmonary Disease- Pre-operative pulmonary testing:
Pulmonary functions testing (PFT) and chest X-rays (CXR)- proven to have limited benefit in predicting peri-operative respiratory failure and complications Decreased serum Albumin levels & Increased BUN = increased risk of peri-operative pulmonary morbidity Predictors- Open aortic, thoracic and upper abdominal procedures are associated with the HIGHEST RISK of peri-operative pulmonary morbidity Cranial, vascular and neck surgeries are associated with a HIGH RISK of peri-operative pulmonary morbidity \*These surgeries lead to decreased vital capacity; decreased FRC; and diaphragmatic dysfunction= hypoxemia and atelectasis\*
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Pulmonary Disease-
Tobacco- Increased carboxyhemoglobin levels Decreased ciliary function Increased sputum production Cardiovascular stimulation from Nicotine \* 4-8 weeks of smoking cessation is needed in order to decrease the incidence of post-operative complications\* (Airways are very Reactive!!)
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Asthma
Find out the patient’s severity! current status; frequency of bronchodilator use; frequency of hospitalization (r/t asthma) and steroid use Consider a “stress dose” if patient takes regular corticosteroids d/t adrenal insufficiency
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OSA- Obstructive sleep apnea
defined as periodic obstruction of upper airway during sleep Leads to chronic sleep deprivation Chronic pulmonary hypertension Right heart failure \* These patients are susceptible to respiratory depressants! Use judiciously!\* OSA Characteristics: Obesity; Large neck; large tonsils; nasal obstruction; upper airway abnormalities Questions- Do you snore? Do you wake yourself up at night from snoring? Are you tired in the daytime? Do you have a hard time breathing?
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•**Endocrine Disease-**•***Diabetes Mellitus-***
The majority of diabetics develop secondary disease in one or more organ systems Increased risk for CAD; HTN; CHF & Peri-op MI Higher incidence of cerebral vascular, peripheral vascular and renal vascular disease DM is the leading cause of renal failure requiring dialysis! Increased peripheral neuropathies= careful positioning Gastroparesis= theoretical increased aspiration risk Stiff joints d/t glycosylation of proteins (could affect airway) Thorough H & P Draw blood glucose on arrival, hgbA1c; Lytes; creatinine and ECG Type 1 Diabetics= hgbA1c \<7.5% Type 2 Diabetics= hgbA1c \<7% - or abnormal lytes or ketonuria = DELAY ELECTIVE SURGERY!! \*optimize these patients then bring them back\* Perioperative sugar management- The periop experience comes with increased serum glucose d/t stress (cortisol and catecholamine release) Glycemic control decreases morbidity, infection rate, stroke incident and improves wound healing Goals- Cardiac surgery= maintain sugar 80-100 mg/dL Goals- non-cardiac surgery= maintain sugar \<200mg/dL Hold oral hypoglycemic meds the day of surgery Continue insulin (consider half dose)
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Endocrine Disease- Thyroid/ Parathyroid Diseases:
Screen for s/sx of hyper/hypothyroidism- Hypo= hypothermia; hypoglycemia; hypoventilation; hyponatremia & heart failure Hyper= THYROID STORM- tachycardia; A-fib; CHF; tremor; muscle weakness & anemia \*enlarged thyroid may create airway difficulty\* Hyperparathyroidism= hypercalcemia (draw Ca++) s/sx= weakness; lethargy; headache; insomnia; apathy; bone pain & epigastric pain
91
Endocrine Disease- Adrenal cortical suppression:
Be suspicious of those on long term steroid use (Cushing’s- moon face; skin striation; truncal obesity & HTN) Make sure that they get a stress dose if steroids were taken for one month or greater within the last 6-12 months (if more than a minor procedure) Max dosing= 100mg hydrocortisone IVP before surgery then q8h x 1 day then 50mgIVP--- highly debated\*
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Endocrine Disease- Renal Disease:
Assess electrolytes Make patient euvolemic prior to induction (likely dry if hemodialysis recently) Be mindful of meds metabolized by kidneys
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Endocrine disease- Liver disease
Coagulopathy (know levels before regional) Decreased plasma proteins- affects drug binding Consider labs if increased ETOH history
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•**Laboratory Test Recommendations-** ## Footnote CBC
CBC- extremes of age; liver or kidney disease; anticoagulant use; bleeding; hematologic disorders; malignancy; type & invasiveness of surgery
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Lab testing Coags
COAGS- liver or kidney disease; bleeding disorder; anticoagulant use; chemotherapy
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Lab testing serum chemistry
SERUM CHEMISTRY (glucose, lytes, renal & liver function)- liver or kidney disease; DM; CNS disease; Endocrine disorder; Elderly; Malnutrition; type & invasiveness of surgery
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Lab testing CXR
CXR- pulmonary disease or clinical findings (r/o pneumonia or pulmonary edema); unstable cardiovascular disease; type & invasiveness of surgery
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Lab testing ECG
ECG- CV disease or clinical findings; pulmonary disease; type & invasiveness of surgery
99
Lab testing pregnancy test
PREGNANCY TEST- possible pregnancy (child bearing years) everyone
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Go forward with surgery?
Are risk factors modifiable? Will delaying the procedure add to peri-op risk or morbidity? What can we do in the peri-op period to decrease this patient’s risk? Do we have enough information to make an informed decision?
101
•**Aspiration Risk**
Emergency surgery Inadequate (light) anesthesia Abdominal pathology Obestity Opiates Neuro deficits Lithotomy Difficult intubation Reflux Hiatal Hernia
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\*\*\*\*Aspiration Risk: Fasting Times-\*\*\*\*
Clear liquids= 2 hour minimum Breast milk= 4 hour minimum Infant formula= 6 hour minimum Non-human milk= 6 hour minimum Light meal= 6 hour minimum
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Aspiration Risk: Medications-
Bicitra: Increases gastric pH in 100% of the cases it is used – Highly effective antacid Famotidine: Increases gastric pH Reglan: Increases gastric emptying (obese; pregnant; diabetics; trauma & emergency surgery)
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Pre-anesthetic Screen
Diagnosis/Procedure Anesthetic/surgical Hx MH/Adverse rxn Airway difficulty Airway Difficult? Sleep Apnea Exam: teeth; mallampati; mouth opening; chin length; neck size and mobility CNS Stroke; mini-stroke; seizures; numbness; tingling; weakness Altered mental status; headaches; neuromuscular disease; spinal cord injury Psych disorders: anxiety, depression.. Etc.. Infectious If/When did you have COVID-19; HIV; MRSA; VRE; influenza; TB; foreign travel- Any Sequalae Age/ Gender/ Height/ Weight Allergies- adverse med reactions Medications Over the counter meds (herbals, illicit drugs) Cardiovascular Congenital heart disease; hypertension; coronary artery disease; heart failure; cardiomyopathy; valvular disease; syncope; arrhythmia; pacer; ICD; vascular disease Chest pain, SOB; racing rhythms; irregular beats; palpitations; able to go up and down stairs without SOB GI/ Hepatic Liver disease; reflux (GERD, Hiatal hernia) Bowel obstruction Alcohol use Renal Insufficiency; failure; dialysis Hematology Anemia; coagulopathy; sickle cell; chemo; transfusions (do this in lay terms) Vital Signs NPO status; IV access; invasive monitors; advanced directives Pulmonary URI; bronchitis; pneumonia; recent cough or cold; asthma - When’s the last time you used a rescue inhaler? Have you ever been hospitalized for your breathing? Endocrine/Metabolic Diabetes; thyroid; rheumatoid arthritis; steroid use
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Legalities of Negligence in Patient Positioning
Problems arising from positioning such as peripheral neuropathies injuries fall under the doctrine “Res ispa loquitur” “the thing speaks for itself” This implies the injury sustained is so evident that it would not have occurred without negligence from someone else Patient only has to prove that there was an injury . . . This is why documenting pre-existing issues is so important
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Types of Nerve Injury Following General Anesthesia
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Goal of close claims project
•The goal of the Anesthesia Closed Claims Project is to identify major safety concerns, patterns of injury and strategies for prevention to improve patient safety by anesthesiologists working in pain management, operating rooms, labor floor, remote locations and critical care.
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Perioperative Neuropathy at night…
Perioperative neuropathy or soft tissue injury when sleeping naturally Wakes us up Hip starts to hurt so we wake up and shift to the other side We can adjust ourselves when something gets uncomfortable Both consciously or unconsciously move and reduce the tissue stretch and compression forces that caused the symptoms
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Mechanisms of Soft Tissue Injury
**\*\*Tissue stretch and compression**\*\* are most commonly associated with positioning-related problems in anesthetized or sedated patients Stretch (especially \> 5% of resting length): Kinks or decreases lumens feeding arterioles and draining venules Direct Ischemia from reduced arteriole blood flow Indirect ischemia from venous congestion Compression: (neuropraxia or axonotmesis) Direct pressure reduces local blood flow and disrupts cellular integrity Results in tissue edema, ischemia and possibly necrosis Padding
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Mechanisms of Positioning Injury
Don’t really know for sure Perioperative Inflammatory Responses Inflammatory neuropathy Microvascular neuropathies Autoimmune disease/Viruses/immunosuppression Radiation-induced Systemic inflammation from drugs
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Goals of Proper Positioning
Gives the surgical team a clear view of the surgical site Provides the best access to the surgical site for the surgeon Gives anesthesia the best position for the optimal administration of drugs Can reduce bleeding before/during/after the surgery Decreases the risk of pressure and nerve related injuries Can prevent or reduce risk of respiratory problems (especially when anesthesia is involved) Prevents/reduces risks associated with circulatory issues
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Team Member Responsibilities
Surgeon - Optimal procedural exposure Anesthesia - Physiologic requirements (ABC’s) -Ongoing assessment -Ensure patient safety Nursing -Safe transfer -Use of adequate padding and positioning aids - Ongoing assessment
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Key Points Associated with Positioning
A through assessment of risk factors for complications related to positioning should be an interral part of the preoperative evaluation A history of surgeries related to positioning. Knee back hip of neck surgery may need special positioning considerations
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Basic Principles of Positioning
Shared responsibility Must document every change and how you protected patient If head, neck or whole body moves must recheck and document breath sounds Hypotension biggest physiologic consequence of position changing Patients are unconscious and relaxed – can often be put in positions not tolerated.
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Common Perioperative Neuropathies
\*\*Ulnar Neuropathies\*\* most common Brachial Plexopathies Median Neuropathies Radial Neuropathies Lower Extremity Neuropathies
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Ulnar Neuropathy
Most COMMON perioperative neuropathy Key factors associated with ulnar neuropathy: Direct extrinsic nerve compression (often medial aspect of elbow) Intrinsic nerve compression (associated with prolonged elbow flexion) Inflammation Male, high BMI, older, prolonged postop bed rest
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Timing of postoperative symptoms
Most develop during postoperative period Studies suggest that those patients that develop ulnar neuropathy experience their first symptoms at least **_24-48_** hours postoperatively Medical patients can also develop ulnar neuropathies during hospitalization
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Anatomy and Elbow flexion
Ulnar nerve passes behind medial epicondyle and under the aponeurosis that holds the two muscle bodies of the flexor carpi ulnaris together Proximal edge of aponeurosis (cubital tunnel retinaculum) is thick, especially in men The retinaculum stretches from the medial epicondyle to the olecranon Flexion of the elbow stretches the retinaculum and puts a lot of stress on the nerve as it passes underneath
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Impact of elbow flexion
**_Ulnar nerve is the only major peripheral nerve in the body that always passes on the extensor side of a joint…….. the elbow!_** All other major peripheral nerves primarily pass on the flexion side Peripheral nerves start to lose function and can develop ischemia when stretched \>5% of their resting length \>90 (110) degree elbow flexion stretches the ulnar nerve
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Positioning the ulnar nerve
Abduct less than 90 degrees Supinate the arm Use padding
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Outcomes of Ulnar Neuropathy
About 40% of sensory-only ulnar neuropathies resolve within 5 days About 80% resolve within 6 months Only a few combined sensory and motor ulnar neuropathies resolve within 5 days About 20% resolve within 6 months and most result in permanent motor dysfunction and pain Compression or stretch injury
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Ulnar nerve injury
Compression at nerve between table and medial epicondyle Prevent by supination, avoid hypotension and hypoperfusion Pad arms properly Manifested by \***inability to abduct the 5th finger** Weakness/ atrophy of hand muscles **\*“claw-hand”\*** Numbness, tingling or pain in the lateral aspect of the hand on the side of the ulnar nerve injury
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Other contributing factors for Ulnar Neuropathy
Patient characteristics prolonged bedrest and high body mass index Men: 1.5 times larger tubercle of the coronoid process, less adipose tissue, thicker cubital tunnel retinaculum Abnormal ulnar nerves before surgery (Contralateral neuropathy) Poorly formed fibrotendinous roof of the cubital tunnel External compression in the absence of stretch
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Brachial Plexus Injury
Most common is patients undergoing sternotomy (especially those with internal mammary artery mobilization) Patients in prone and lateral have a higher risk than supine Things to think about: Brachial plexus entrapment Prone positioning Anatomy of shoulder abduction
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Brachial Plexus Entrapment
Prone and lateral position patients Brachial plexus can become entrapped between compressed clavicles and rib cage Prone position Better if arms can be tucked Some patients can have somatosensory-evoked potential changes when their arms are abducted (surrender position)
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Causes of injury to brachial plexus
Shoulder braces may compress nerve roots and stretch the plexus Turing the head (unconscious patient) may stretch the brachial plexus Spreading the sternal retractor causes the clavicle and rib to pinch the plexus. Unilateral retraction may cause stretching of the nerves.
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Brachial plexus pic
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Anatomy of shoulder abduction
Abduction \> 90 degrees places the distal plexus on the extensor side of the joint and possibility of stretching the plexus Goal is to avoid abduction \>90
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Brachial plexus injury - occurs from
Excessive external rotation or abduction of arm Avoid \> 90 degree abduction Avoid arm falling off of table! Watch lateral head rotation If prone watch flexion and abduction of arms overhead Lateral position requires an axillary (chest) roll which avoids compression of humerus into axilla
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Long Thoracic Nerve Dysfunction
Scapular winging Serratus anterior muscle that is supplied by the long thoracic nerve that branches immediately from C5-C7, sometimes C8 Long thoracic nerve palsy allows the dorsal protrusion of the scapula Traumatic in nature Viral/inflammatory?
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Nerve Injury - what happens median, axillary, ulnar, musculocutaneous, radial
Manifestations depend on which nerves are injured in the plexus: Median – “Ape hand” deformity, inability to oppose thumb - Muscular men with large biceps are susceptible to median nerve injury if the arm is fully extended during surgery Axillary – inability to abduct the arm Ulnar – “Claw hand” deformity Musculocutaneous – inability to flex forearm Radial – wrist drop
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Axillary Neurovascular Injury
Abduction of the arm on the arm board \> 90 degrees Head of the humerus into the axillary neurovascular bundle Compression and stretch injury Compression or occlusion of vessels with decreased perfusion Mastectomy
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Median Neuropathies
Mostly in men between 20 and 40 years old Men with large biceps and decreased flexibility Prevents complete extension at the elbow Creates a shortening of the median nerve over time Usually motor dysfunction and don’t readily resolve Around 80% with motor dysfunction are still there 2 years after initial onset IVs in the antecubital area Things to think about: Stretch of the nerve: nerves become ischemia if stretched \>5% of their resting length which can kind penetrating arterioles and exiting venules decreasing perfusion pressure Arm support
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Arm Support
When muscular men are anesthetized, their arms are fully extended at the elbow and placed on armboards Full extension of the elbow stretches chronically contracted median nerves and promotes ischemia (at the level of the elbow) Very important to support/pad the forearm and hand to prevent full extension
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Radial Neuropathies
More common that median neuropathies Injured more often by direct compression (in contrast to median nerve injury due to stretch) Radial nerve injury is usually compression of the nerve in the mid-humerus area (arising from roots C6-8 and T1) Things to think about: Surgical retractors: compression of radial nerve by bars used to hold abdominal retraction holders Lateral position (impinged by overhead arm boards) Unsupported arms/ poles/ repeated cycling of the BP cuff
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The Third Amigo….
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radial nerve pic
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Radial Nerve Injury
Can be injured if compressed against spinal groove of humerus and other object (ie. Either screen or excessive cycling NIBP Symptoms include wrist drop, weakness of abduction of thumb and loss of sensation in web space between thumb and index finger.
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Lower Extremity Neuropathies
Common peroneal Sciatic nerve Obturator nerve Lateral femoral cutaneous nerve Femoral nerve
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do you need to be careful positioning the hip?
Great care must be exercised when placing the hip in unusual positions. Excessive flexion or abduction can injure the lateral femoral cutaneous or obturator nerves respectively.
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Obturator Neuropathy
Hip abduction \>30 degrees can cause strain on obturator nerve Obturator passes through the pelvis and out the obturator foremen Excessive hip flexion of thigh can cause compression Excessive traction in abdominal Sx Motor dysfunction is common Inability to adduct the leg with decreased sensation over the medial side of the thigh
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Lateral Femoral Cutaneous Nerve
Prolonged hip flexion \>90 degrees can cause ischemia One third of the nerve’s fibers pass through the inguinal ligament as it passes through the thigh (originates at L2-3) Hip flexion \>90 degrees causes lateral displacement of the anterior superior iliac spine and stretch of the inguinal ligament Nerve fibers are compressed by the stretch and can become ischemic and dysfunctional This nerve carries \*\*\***only sensory fibers**\*\* so no motor disability occurs But can have disabling pain and dysesthesias of the lateral thigh
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Sciatic Nerve
Can be stretched with external rotation of the leg Sciatic and its branches (common peroneal and tibial nerves) cross the hip and knee joints and are stretched by hyperflexion of the hips and extension of the knees
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Peroneal Neuropathy
Usually associated with direct pressure of the lateral leg, just below the knee, where the peroneal wraps around **head of the fibula** Injured by leg holders (candy cane) that hold the leg and foot Impinge the nerve around the head of the fibula Can cause prolonged foot drop and trouble ambulating
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Saphenous Nerve Injury
May be injured when the medial tibial condyle is compressed by leg supports May be injured during difficult forceps delivery or by excessive flexion of the thigh to the groin
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Physiological changes related to change in body position
Most changes are related to gravitational effects on cardiovascular and respiratory systems Changes in position redistribute blood within the venous, arterial, and pulmonary vasculature Pulmonary mechanics also change with varying body positions
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Cardiovascular changes with Positioning
Changing from erect to supine increases venous return and stroke volume Parasympathetic stimulation regulate heart rate and contractility to adjust to increased preload Obesity (wedge under Rt hip), pregnancy, and abdominal tumors can reduce venous return (preload) when in the supine procedure
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Starling’s Law
The Frank-Starling law states that the force or tension developed in a muscle fiber depends on the extent to which the fiber is stretched. In a clinical situation, when increased quantities of blood flow into the heart (increasing preload), the walls of the heart stretch.
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Pulmonary changes with Positioning
In supine position, functional residual capacity and total lung capacity are reduced due to changes to the diaphragm This is exaggerated in obese patients Anesthesia and muscle relaxants further reduce these volumes due to diaphragm position with relaxation Trendelenburg position also reduces lung volumes Any position that limits movement of the diaphragm, chest wall or abdomen may increase atelectasis and intrapulmonary shunt
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Common Surgical Positions list:
_Four basic surgical positions:_ Supine Prone Lithotomy Lateral _Variations_ Trendelenburg Reverse Trendelenburg Fowlers Jackknife High and low Lithotomy
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Supine
Patient on back Arms on arm boards or tucked Check orientation of arm (arms \< 90 degrees) Make sure arm is supinated (palm up) Place additional padding under elbow if able Check fingers Check IV lines and SaO2 probe FRC is decreased by 20% Abdominal contents limit movement of the diaphragm Decreased muscle tone from GA Small airways close sooner  hypoxia VQ changes cause shunting hypoxia Obesity and pregnancy problems Compression of the IVC Pressure on occiput alopecia Pad back of head Check often in long cases Keep hips and knees slightly flexed Blanket/ pillow under knees Legs uncrossed Heels, occiput and elbows padded Cervical, thoracic and lumbar spines should be in straight alignment Arms If at side must be padded and tucked Watch fingers !!!!! On arm boards Padded, palms up (supinated) less than 90 degree angle
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Complications of Supine
Peripheral neuropathies which can occur in any position Backache Ischemic pressure injuries Pressure Alopecia Prolonged compression of hair follicles produce hair loss Pain and swelling where the occiput has been supporting weight in the head down position Associated with tight face mask straps, hypotension and hypothermia Pressure-Point issues Hypothermia and vasoconstrictive hypotension Heels, sacrum and elbows
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Arm Restraints
Restraint too tight Pressure compresses the anterior interosseous nerve (branch of the median nerve) in the upper forearm Can resemble compartment syndrome in the lower extremity
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Nerve Injury and Supine Position
Brachial plexus neuropathy Sternal retraction Long Thoracic Nerve Injury Axillary trauma from humeral head Radial nerve compression Median Nerve Dysfunction Ulnar Nerve Neuropathy Back pain Compartment syndrome
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Lateral Decubitus
Positioned on side often with assistance of supports or bean bag Arms parallel and padded Maintain good anatomical alignment Pillow between legs and feet Keep bottom leg flexed to stabilize the trunk Chest roll placed Check radial pulse of dependent arm
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Chest Roll
Support placed caudad to the downside axilla Axillary Roll??? Lifts the thorax enough to relieve pressure on the axillary neurovascular bundle Helps prevent decreases in blood flow to the hand and arm Questionable Decrease shoulder pain after postop
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Common Peroneal Injury and Lateral Position
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Flexed Lateral Decubitus
Flexion should be under the iliac crest Chest roll Neck neutral Pillow between knees and flexed Padding under ankles/feet
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Flexed Lateral Position
Flip the table so the flank and thorax are horizontal Feet/legs below the atria causing pooling of blood Lumbar stress Thoracotomy Not very common For Kidney surgery: Lateral jackknife with elevated kidney rest
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Lateral decubitus
VQ mismatching: Dependent lung: Underventilated More perfusion Nondependent lung: Overventilated Less perfusion Causes incr. VQ mismatching hypoxia
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Lithotomy
Patient is supine with arms extended laterally \<90 degrees Each lower extremity is flexed at the hip (about 90 degrees) and knees bent parallel to the floor **Extremities should be elevated and lowered slowly and together** Seen most often in GYN and Urology cases Hip flexion \>90 degrees can increase stretch of the inguinal ligaments
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Lithotomy Stirrups
Various types of stirrups Candy cane Allen stirrups Knee cradles Move legs at same time when positioning patient in and out of lithotomy
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Lithotomy Positions low high exaggerated
**Low:** About 30-45 degrees Reduces perfusion gradients **High**: Suspend the patients feet high with stirrups Patient’s legs almost fully extended on the thighs flexed 90 degrees or more on the trunk Significant uphill gradient for arterial perfusion to the feet Avoid hypotension Stretch of sciatic nerve Compression of femoral canal by inguinal ligament **Exaggerated** Pelvis flexed ventrally on the spine, thighs forcibly flexed on trunk and lover legs aimed skyward Associated with compartment syndrome
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things to think about Lithotomy
Can auto transfuse up to 500 cc of blood Remember this will shift back when legs go down and can cause a decrease in BP Can impair ventilation due to upward pressure More prominent in obese pt’s Nerve injuries !!!! Most common problem with lithotomy Injuries: Sciatic, common peroneal, femoral, saphenous and obturator Hand injury (fingers in bed)
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Common Peroneal Nerve
Common peroneal nerve damage Occurs from compression of lateral aspect of fibula head (improper padding against stirrups) FOOT DROP Elevate and flex simultaneously Avoids stretching of one side of the nerve \> 4 hrs in lithotomy increases risk of injury Ischemia, edema to skin and muscles
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Femoral Nerve
Femoral nerve injury Excessive angulation of the thigh on the abdomen Excessive traction during abdominal Sx Decreased flexion of the hip Decreased extension of the knee Loss of sensation over superior aspect of the thigh and medial or anteromedial side of the leg
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acute compartment syndrome of hand
In the immediate postoperative period, she developed compartment syndrome of the right hand that required multiple fasciotomies and multidisciplinary management by plastic surgery, orthopedics, and rehabilitation medicine. Acute compartment syndrome of the hand is a potentially devastating and infrequent condition observed after trauma, arterial injury, or prolonged compression of the upper limb
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Compartment Syndrome
Perfusion to an extremity is inadequate Characterized by ischemia, hypoxic edema, elevated tissue pressure within fascial compartments and extensive rhabdomyolysis Lateral position(arm) and lithotomy (legs) Associated with: Systemic hypotension and loss of driving pressure to the extremity (elevation) Vascular obstruction from excessive flexion, knee or pelvic retractors External compression from straps Lithotomy for \>5 hours common factor
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Prone Position
Used for posterior fossa of the skull, posterior spine, buttocks and perirectal and lower extremities (Achilles) Head neutral ET tube placement and patency Check bilateral eyes/ears for pressure points Head turned Check dependent eye/ear ETT placement Be aware of potential vascular occlusion Arms at side or “surrender position” \< 90 degrees to prevent stretching of brachial plexus
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Supine to Prone
Need multiple people to assist Disconnect all lines/monitors if possible Patient is log rolled gently so there are no abnormal movements or twisting of body parts Using normal ROM arms are placed beside the pt’s head or brought down to the sides of the body Chest rolls from below clavicles to iliac crest Provide adequate lung expansion and help alleviate pressure on abdomen Protect male genitalia and female breasts Full monitoring reinstituted ASAP, ET tub positioning reconfirmed
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Prone
Pillow under lower legs and ankles help flex knees and prevent pressure on toes Head on special pillow with cut out area free of pressure on face/eyes Head positioned to side may impair drainage on one side or neutral Elastic stockings and active compression to minimize pooling of venous blood Cardiac: Compression of abdominal viscera Pooling of blood in extremities Decreased preload, CO, BP, SV Increased SVR and PVR Pulmonary Decreased total lung compliance Increased work of breathing ETT dislodgement Other Check and document face and eye free of pressure every ? min Blindness from retinal ischemia ION- Ischemic optic neuropathy Corneal abrasions
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Reverse Trendelenburg
Cholecystectomy, head and neck procedures Shifts the abdominal contents caudad Prevent patients from slipping off the table May have hypotension may result in decreased venous return and perfusion to brain Facilitates exposure, aids in breathing (increased FRC)
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Trendelenburg
Causes further pressure upwards on diaphragm from abdominal contents and further decreases lung expansion Increases ICP by decreasing venous drainage Increased IOP (pt with glaucoma) Activation of baroreceptors ^ pressure; ^ baroreceptor discharge; inhibits systemic vasoconstriction(SNS) & enhances vagal tone Increased risk of aspiration Mendelson syndrome: aspiration of \> 25cc of gastric contents with a pH of \< 2.5
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What are the physiologic effects and risks associated with Trendelenburg position?
Further increases translocation of blood to central compartment (along with lithotomy) Intracranial and intraocular pressure increases What should you think about before extubation? Facial and upper airway edema (Can the patient breath around the ET tube with the cuff deflated) What pulmonary changes can occur? Decrease in pulmonary compliance, FRC and vital capacity Shoulder braces and brachial plexus injury
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What injuries can occur to the eye?
What is the most common injury to the eye? Corneal abrasion What are some other injuries to the eye? Chemical injury, direct trauma (pressure and crush), blurred vision
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How does the head position affect the position of the ET tube?
Flexion of the head may move the endotracheal tube toward the carina; extension moves it away from the carina. A general rule is that the tip of the endotracheal tube follows the direction of the tip of the patient’s nose. Sudden increases in airway pressure or oxygen desaturation may be caused by mainstem bronchial intubation.
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Sitting (Beach Chair)
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_Awake_ Vs Anesthetized in Sitting Position
Awake- MAP, SV, CO, PaO2 all decrease Alveolar-arterial oxygen gradient and pulmonary and vascular resistance all increase An autonomic response helps compensate for the above by increasing SVR by up to 50-80% Cerebral perfusion pressure decreases by about 15%
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Awake Vs _Anesthetized_ in Sitting Position
General Anesthesia: * The autonomic response is inhibited by general anesthesia causing vasodilation and decreased CO * GA causes vasodilation, myocardial depression, and impaired venous return that further impairs cerebral blood flow
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More Physiologic Changes in Beach Chair
Flexion of the head may obstruct the internal jugular and cause cerebral venous engorgement or hypoperfusion (swelling in the face, eyes) Extension of the head can impair cerebral blood flow causing cerebral ischemia, obstruction of ET and pressure on the tongue
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\*\*\*\*Cerebral Perfusion Pressure (CPP)\*\*\*\*
Cerebral vasculature dilates and constricts to maintain constant blood flow to the brain CPP = MAP – ICP (or CVP) Autoregulation occurs when MAP in between 50 and 150 m Hg Poorly controlled HTN the curve is shifted higher to the right
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CPP and BP in Sitting Position
Supine: BP in arm is similar to CPP in the absence of ICP Beach chair: MAP and BP in the arm is higher than Cerebral perfusion Monitored at external auditory meatus (represents the base of the brain) which is about 20 cm above the heart (15 mm Hg difference) Cuff site (blindness and stroke due to inaccurate BP ) 1 mm Hg decrease/1.35 cm height (20 cm ~ 15 mmHg change)
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Sitting Position Complications
Potential complications from sitting position **Venous air emboli** Need to take measures to detect and extract VAE Hypotension (fluids, vasopressors, decrease agent) Brainstem manipulations resulting in hemodynamic changes Risk of airway obstruction Decrease venous return (stockings or compression devices) Macroglossia (avoid chin against chest)
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Midcervical Tetraplegia
Hyperflexion of the neck, with or without rotation of the head Stretching of the spinal cord resulting in compromise of the vasculature of the midcervical region Paralysis below the general level of the 5th cervical vertebra Sitting position Prolonged head flexion for intracranial surgery in the supine position
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Sitting Position……..VAE
VAE: venous air embolism Caused by open venous system above level of the heart Atmospheric pressure \> venous pressure and vein sucks air in Detection by listening to heart sounds with Doppler at R 2nd intercostal space A sudden decrease in CO2, hypoxia, arrhythmias, hypotension and a millwheel murmur (usually a late sign)
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Venous Air Embolism Treatment
Stop the problem Flood area with water if necessary 100% O2 and Stop N2O Aspirate from CVP Durant’s position Vasopressors Get ready to do CPR
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Face Masks
Can cause pressure damage over nose Facial nerve damage from fingers over mandible Face straps can cause injury or even necrosis to face, ears and eyes and alopecia
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Visual Injuries
Corneal abrasions are the most common Chemical irritation from preparation solutions Direct trauma from face mask Pressure from the hands while intubating Pressure effects from lateral and prone position Poor eye taping techniques Blindness more rare Etiology probably ischemic optic neuropathy Large volume blood loss Prolonged hypotension Duration of surgery Prone or lateral position Edema Patient’s at Risk DM Smokers Obese ETOH abuse Anemic HTN Consent ALL Patient’s at Risk
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Potential Etiology of POVL
Acute venous congestion of the optic canal Wilson Frame Head is lower than the heart Obesity can increase intraabdominal pressure in prone patients Long durations All the above can contribute: to venous congestion in the optic canal reduction of optic nerve perfusion pressure perioperative visual loss. Thought about possibility of visual loss. People need to know it’s a possibility during consent… prone spine surgery- does pt want to know about it 80% of pts want to know… Closed practice claims 5% are for the eye- ( most common is corneal abrasion. ION ischemic – neuropathy .8 % and corneal is just 1%. Done surgery if only ive known about blindness I would not have done the procedure. Had to describe it – who will bear responsibility – surgeon cant be pt didn’t understand and anesthesia would check to make sure they understand if didn’t would not start till pt understood. Rare event ION place extreme stroke even death above vision.
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Ways to Help prevent eye?
Reduce venous congestion in the optic canal Keep head above the heart or at the same level Colloids vs Crystalloids Reduce intra-abdominal pressure Limiting duration of surgery
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Prevention is the best practice
Avoid positions that permit stretching of the nerves Avoid pressure to areas that carry nerves prone to injury (ulnar cubital tunnel, peroneal) Padding and support should distribute weight over wide areas Patients position should be neutral whenever possible Anesthesia and muscle relaxants increase malposition injuries Extremes of weight is obviously a risk ASK the patient what is comfortable
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Which patients should we position before inducing anesthesia?
Patients with a history of back pain or previous surgery Patients with history of knee and hip arthroplasty Neck pain Shoulder pain Rheumatoid arthritis Anyone that complains of pre-existing injury…. ALWAYS CHART WHAT YOU DID (patient positioned for comfort in stirrups before induction, neck neutral, hands padded per patient request and comfort)