Test 2 Steroids Flashcards
(33 cards)
Westcort®
- hydrocortisone valerate
- potent
- topical -> poison ivy, contact dermatitis
- relief itching or skin inflammation
- caution with dermatological infections (ex. fungal infections)
- ointment or cream 0.2%
Cortef®, Cortenema®
- hydrocortisone
- oral: long term use for patients who do not produce cortisone
- enema: used for digestive hyper-immune diseases
Solu-Cortef®
- hydrocortisone
- Endocrine disorder / inflammatory disorders
- Systemic injectable
Deltasone®
- prednisone
- Treatment of allergic & inflammatory diseases
- tapered doses for allergic reactions
- Metabolized to prednisolone
- 5-60mg/day
Orapred®
- prednisolone
- Treatment of allergic & inflammatory diseases
- pay attention to solution concentration
Medrol®
- methylprednisolone
- Treatment of allergic and inflammatory diseases
- 4mg dosepak
- common side effect: insomnia
Solu-Medrol®
- methylprednisolone
- acute treatment of allergic & inflammatory diseases
- systemic injection
- used in ER
Decadron®
- dexamethasone
- Treatment of allergic & inflammatory diseases and asthma
- Note concentration with liquid dosage form 1 mg/mL vs. 0.5mg/5 mL
- potent
- dosepak not used often
Celestone®
- betamethasone
- potent
- Treatment of allergic & inflammatory diseases
- Topical and injectable dosage forms
- Topical foam, injectable suspension
Kenalog®
- triamcinalone
- inflammation
- injection and cream
- doctors use this with special formulations
Nasacort AQ®
- triamcinalone
- Chronic treatment of allergic rhinitis
- 2 sprays in each nostril daily
Flonase®
- fluticasone propionate
- Flonase Allergy is an OTC product (2 sprays in each nostril daily for a week and taper down to 1-2 sprays daily)
- prescription: may start with loading dose: ii sprays in each nostril BID, down to ii sprays each nostril QD
- Therapeutic effects are not seen immediately
- suspension: shake well before use
Veramyst ®
- fluticasone furoate
- different ester form of fluticasone
- Rx only
- used for allergic rhinitis
- Therapeutic effects are not seen immediately
- suspension: shake well before use
- 2 sprays in each nostril daily
Flovent ® MDI
- fluticasone
- Chronic treatment of asthma
- Therapeutic effects are not seen immediately
- high potency
- 3 strengths: 44, 110, 220 mcg
Advair ®
- salmeterol and fluticasone
- Steroid & Long-Acting-Beta-2 agonist combination
- chronic treatment of asthma: one puff BID 150/50, 250/50, 500/50
- COPD: one puff BID 250/50
Symbicort ®
- budesonide and formoterol
- MDI
- Steroid & Long-Acting-Beta-2 agonist combination
- Chronic treatment of asthma: start at 80/4.5 strength, after 2 wk increase to higher strength if need
- Chronic treatment of COPD: 160/4.5 mg
- 2 inhalations BID
Pulmicort®
- budesonide
- Chronic treatment of asthma
- Available as a solution for nebulization Pulmicort respules (only steroid that has a nebulizer solution )
- BID dosing
Rhinocort AQ®
- budesonide
- Allergic rhinitis
- for chronic treatment
- there is a OTC product
- start with two sprays daily then decrease to one spray in each nostril daily
Principles of Asthma treatment
- prevent symptoms by reducing inflammation
- must be taken daily
- do not expect quick relief
- acute / rescue meds used to treat active asthma attack or bronchospasm
key indicators for considering diagnosis of asthma
- wheezing
- history of: cough, wheeze, chest tightness, diff. breathing
- symptoms occur / worsen in the presence under certain circumstances
- symptoms occur / worsen at night
possible asthma if symptoms occur / worsen in the presence of these conditions
- Exercise
- Viral infection
- Animals with fur or hair
- House-dust mites (in mattresses, pillows, upholstered furniture, carpets)
- Mold
- Smoke (tobacco, wood)
- Pollen
- Changes in weather
- Strong emotional expression (laughing or crying hard)
- Airborne chemicals or dusts
- Menstrual cycles
Goals of therapy to achieve asthma control
♦ Prevent chronic and troublesome symptoms
♦ Require infrequent use (≤2 days a week) of inhaled SABA for quick relief of symptoms
♦ Maintain (near) “normal” pulmonary function
♦ Maintain normal activity levels
♦ Meet patients’ and families’ expectations of satisfaction with asthma care
♦ Prevent recurrent exacerbations of asthma and minimize the need for ED visits
♦ Prevent progressive loss of lung function; for children, prevent reduced lung growth
♦ Provide optimal pharmacotherapy with minimal or no adverse effects
What are common side effects with steroids?
♦ short-term - insomnia - upset stomach (take with food) - increased appetite -> weight gain ♦ long-term - increased blood pressure / sugar - moon face - osteoporosis - decrease growth of children - increased susceptibility to infections - adrenal suppression - peptic ulcer disease
Qvar®
- beclomethasone
- inhaled corticosteroid
- for chronic asthma
- 40/320 inhale BID