Test 2 (Week 5) Flashcards
(86 cards)
endometroid adenocarcinoma is associated with which specific gene mutation?
PTEN
Vulvar melanoma is mucin, PAS stain _____.
negative
Why does Prempro suck so bad that it’s trial got canceled?
increased risk of heart attacks, stroke, breast cancer, and blood clots
What’s Mifepristone (RU 486) used for?
abortifacient; combined w/ misoprostol
Brenner tumors have a predominant stromal component with island of _____.
transitional epithelium (look like bladder epithelium)
where do follicle cysts originate?
enraptured Graffian follicles
What is Chandelier sign?
cervix is tender (moving abscess) and painful to patient
What are the possible side effects of infertility treatment?
ovarian hyperstimulation, pulmonary complications (atelectasis and ARDS), CV complications (thrombosis and embolism)
abnormal vaginal discharge with strong “fishy” odor =
bacterial vaginosis
What causes bacterial vaginosis?
Replacement of lactobacilli and normal flora with overgrowth of anaerobic bacteria; this alters the normal vaginal environment
What’s the most common cause of bloody nipple discharge?
intraductal papilloma
extramammary Paget’s disease is mucin, PAS stain ____.
postive
What’s the only place you can cultivate pathogenic Treponema palladium?
rabbit testes.
What’s the major side effect of Diethylstilbestrol (DES)?
teratogenic; increased risk of child developing vaginal or cervical cancer if used in utero
Most common breast tumor in adolescent and young adults
fibroadenoma
What’s the most common causes of Salpingitis?
chlamydia or gonorrhea
How does serous “papillary” carcinoma spread?
–Spread through the fallopian tubes to the peritoneal cavity, thus worse prognosis –Lacks cell-surface adhesion molecules; spreads via exfoliation
What’s the causative agent of syphillis?
Treponema pallidum
Which cell type predominates in chronic endometritis ?
plasma cells
What’s the most common cause of anovulatory cycle?
obesity; peripheral fat makes estradiol
What is Fitz-Hughes-Curtis syndrome?
perihepatitis caused by chlamydia and gonorrhea on liver; can see “violin string” adhesions of parietal peritoneum to liver
What’s the shape of Treponema pallidum
corkscrew
What stain can you use to diagnose extramammary Paget’s disease?
mucin stain +
What is endometriosis?
Endometrial glands, stroma or both outside the uterine corpus.