test Flashcards

(39 cards)

1
Q

glucagon and adrenaline decrease the concentration of

A

fructose 2 6 biphosphate

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2
Q

glucagon increases the levels of

A

phosphoenolpyruvatecarboxykinase

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3
Q

how does glucagon and adrenaline affect pyruvate kinase to encourage gluconeogenesis to occur?

A

by phosphorylating pyruvate kinase

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4
Q

What is bypass 1 in gluconeogensis?

A

to overcome pyruvate kinase pyruvate carbocylase is used instead which form oxaloacetate
This is transformed to phosphoenol pyruvate by phosphoenolpyruvatecarboxykinase

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5
Q

What is bypass 2 in gluconeogensis?

A

to transform fructose 1 6 biphosphate to fructose 6 phosphate
fructose 1 6 biphophatase is used instead.

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6
Q

What is bypass 3 in gluconeogensis?

A

glucose 6 phosphate is converted to glucose

by glucose 6 phosphatase

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7
Q

In the electron transport chain what is complex I called?

A

NADH Q oxidoreductase

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8
Q

In the electron transport chain what is complex II called?

A

succinate q reductase

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9
Q

In the electron transport chain what is complex III called?

A

Q cytochrome c oxidoreductase

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10
Q

In the electron transport chain what is complex IV called?

A

cytochrome c oxidase

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11
Q

What does complex I in the electron transport chain do?

A

4 protons are pumped across for every pair of electrons that pass through

ubiquinone is turned into ubiquinol

via NADH

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12
Q

What does complex II in the electron transport chain do?

A

FADH2

ubiquinone to ubiquinol

no protons are pumped across

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13
Q

What does complex III in the electron transport chain do?

A

4 protons are pumped across and electrons go to cytochrome c

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14
Q

What does complex IV in the electron transport chain do?

A

accepts electrons from cytochrome c and transfers electrons to oxygen to make water

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15
Q

Draw the critic acid cycle:

A

Molecules:
Can I keep selling sex for money officer?

Enzymes:
So, At a dance donavon sipped down five drinks

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16
Q

The larger the value of Ka the _______ the value of the Kd

17
Q

What is the overall equation for the critic acid cycle?

A

Acetyl coA + 2 water molecules —> 2 CO2 + 3NADH + FADH2 + GTP

18
Q

What is the overall equation for glycolysis?

A

glucose —-> 2 pyruvate + 2NADH + 2ATP + 2 water molecules

2ATP is from phosphoglycerate kinase
2 water molecules is from enolase

19
Q

Name the three enzymes in the pyruvate dehydrogenase complex and what they produce:

A

E1 - pyruvate dehydrogenase - CO2
E2 - dihydrolipoyl transacetylase - acteyl coA
E3 - dihydrolipoyl dehydrogenase - NADH

20
Q

What are the 5 fates of pyruvate?

A
ethanol 
lactate
alanine 
oxaloacetate 
acetyl coA
21
Q

What is phosphofructokinase affected by?

A

activated by AMP and ADP
activated by fructose 2 6 biphosphate

inhibited by ATP
inhibited by citrate

22
Q

What is hexokinase affected by?

A

inhibited by glucose 6 phosphate

23
Q

What is pyruvate kinase affected by?

A

inhibited by ATP
inhibited by acetyl coA

activated by fructose 1 6 biphosphate

24
Q

Draw glycolysis out:

A

Molecules:
Gross guys favour butts, but good and dreamy boy 4Ps

Enzymes:
Hungry peter pan and the growling pink panther eat pies

25
chitin has what special feature and what glycosidic linkage?
beta 1-4 | with nitrogen appendage
26
cellulose linkage?
beta 1-4 | straight chains
27
amylopectin and glycogen similarities and differences?
alpha 1-4 and alpha 1-6 | branched except glycogen is more branched
28
amylose linkage?
alpha 1-4 | forms a sphere with OH groups facing outwards so more soluble in water
29
Draw the hill plot for an allosteric enzyme
do it
30
draw LB graph
do it
31
Mecelis Menten equation does not apply to the
homotropic effect
32
What is a holoprotein?
an apoprotein with its prosthetic group
33
What is the structure for immunoglobin domains?
2 layers of antiparallel beta sheets are stacked face to face and a fold occurs once in constant region and one in the variable region
34
What is special about histidine?
it is found in the active sites of most enzymes since it has a pka of 4-8
35
What is special about glycine?
it is small flexible and fits into small spaces
36
proline
causes kinks
37
beta sheets are
flexible
38
when u add a reducing agent how does this denature proteins?
breaks disulphide bonds
39
when u add a rorganiz solvent or a detergent how does this denature proteins?
breaks hydrophobic interactions