Test 76: Derm Flashcards
(43 cards)
Hansen disease infects what organs
skin and nerves
Infection of Hansen disease can be associated with contact with what
Armadillo
Difference b/w Tuberculoid leprosy and Lepromatous leprosy
Tuberculoid: Th1 immune
Lepromatous: Th2, lethal
Merocrine glands release what
watery security product via exocytosis with no loss of cell membrane
Apocine glands secrete
membrane-bound vesicles containing the secretory product
Holocrine galnds release
entire content of cells via cell lysis
What type of glands are involved with acne
Sebaceous gland which is a type of holocrine gland
Exposure to what rays causes photoaging
UVA
What happens in photo aging of skin
- epidermal atrophy
- flattening rete ridges
- decrease collagen fibril production
- increase degradation of collagen and elastin in dermis
- increase cross-linking of collagen
Axillary lymph node dissection is a risk factor for the development of what?
Chronic lymphadema involving the ipsilateral arm
- predisposes to angiosarcoma
Stewart-Treves Syndrome
angiosarcoma
What is Cherry Hemangioma
- Benign capillary hemangioma of elderly
- Does not regress
- frequency increases with age
What is strawberry hemangioma
- Benign capillary hemangioma of infancy
How does strawberry hemangioma present
- appears first few weeks of life
- grows rapidly
- regresses spontaneously by 5-8 years
4 year old caucasion male has recurrent skin and respiratory infections. Light skin and silvery hair. Horizontal nystagmus. Peripheral blood smear: giant cytoplasmic granules in neutrophils and monocytes
Chediak-Higashi syndrome
Wiskott-Aldrich syndrome
- Eczema, thrombocytopenia
- combined B and T disorder
Chediak-Higashi syndrome is a defect in what
neutrophil phagosome lysosome fusion
Poison ivy dermatitis produces what in skin
Urushiol
- causes immune response
Androgenetic alopecia causes hair loss primarily where on head
anterior scalp and vertex
What is the main pathogenic factor for androgenetic alopecia
Dihydrotestosterone (DHT)
MOA for Finasteride
5alpha reductase inhibitor
Inheritance pattern for androgenetic alopecia
Polygenic inheritance
What is used to treat alopecia areta
intralesional glucocorticoids
Terbinafina is used to treat what
Tinea capitis
