test2

Question 1

metacentric chromosome position

Answer 1

in the middle

Question 2

Submetacentric chromosome

Answer 2

off center

Question 3

Acrocentric

Answer 3

Near one end

Question 4

Telocentric

Answer 4

is at one end

Question 5

what is pleitrophy

Answer 5

a single gene with multiple phenotype effects

Question 6

what is marfan syndrome

Answer 6

• is autosomal dominant
• encodes connective tissue fibrillin
• causes aneurisms, eye defects, weak bones

Question 7

what are the effects of Porphyria Variegata

Answer 7

-red urine, delirium, abdominal pain

Question 8

Amorph

Answer 8

null mutation(loss of function)

Question 9

Hypomorph

Answer 9

reduced expression of gene product(partial loss)

Question 10

Hypermorph

Answer 10

Increased expression of gene function

Question 11

Neomorph

Answer 11

New function of mutant protein

Question 12

Antimorph

Answer 12

New activity that effects wild type function

Question 13

Overview of meiosis (what happens)

Answer 13

chromosomes duplicate once, nuclei divide twice (2N->n)

Question 14

What happens in Prophase 1

Answer 14

Crossing over occurs

Question 15

what happens in prophase 1- leptotene

Answer 15

chromosomes thicken

Question 16

what happens in prophase 1- zygotene

Answer 16

homologous chromosomes enter synapsis

synaptoneal complex forms

Question 17

what happens in prophase 1- pachytene

Answer 17

synapsis is complete

crossing over occurs

Question 18

whats happen in prophase 1- diplotene

Answer 18

synaptic complex dissolves

tetrad of 4 chromosomes is visable

Question 19

what happens in prophase 1- diakinesis

Answer 19

chromatids thicken and shorten

Question 20

what happens in metaphase 1

Answer 20

tetrads line along middle

Question 21

what happens in telophase 1

Answer 21

Nuclear envelope reforms (2 sis chromatids)

Question 22

swyer syndrome

Answer 22

2n=46, XY

don’t develop female secondary characteristics

Question 23

Androgen Insensitivety syndrome

Answer 23

2n=46yy

lack of androgen receptors

Question 24

klinefelter syndrome

Answer 24

47, XXY
genatilia and internal male
result of nondisjunction event

Question 25

Turner Syndrome

Answer 25

45XO female external genetalia + internal result of nondisjunction event

Question 26

47,XXX syndrome

Answer 26

some phenotypically normal, while some have underdeveloped secondary characteristics

Question 27

47, XYY condition

Answer 27

phenotypically male, usually over 6 f

Question 28

dihybrid cross ratio

Answer 28

9:3:3:1

Question 29

9:7 ratio indicates

Answer 29

complementary gene action

Question 30

9:3:4 ratio indicates

Answer 30

``` recessive epistatis (labradors, ee masks effect of B) ```

Question 31

12:3:1 ratio indicates

Answer 31

dominat epistasis 1 the dominant allege of one gene masks both alleles of the other gene (grey horses)

Question 32

13:3 ratio indicates

Answer 32

dominant epistasis 2 | the dominant allele of one gene masks the dominant allele of the other gene

Question 33

15:1 ratio indicates

Answer 33

Redundant gene | only one dominant allele of 2 genes is necessary to produce phenotype

Question 34

Frans Janssens

Answer 34

observed chiasmata at chromosomes during prophase of meiosis 1

Question 35

T.H Morgan

Answer 35

Suggested chiasmata were sites of chromosome breakage + exchange

Question 36

Creighton/ McClintock

Answer 36

direct evidence that recombinant depends on reciprocal exchange of chromosomes

Question 37

Sturtevant

Answer 37

proposed that recombinant frequencies could be used as a measure to measure distance