Testing

Question 1

What is ENG and what is it used for?

Answer 1

ENG = electronystagmography

helps diagnose vertigo

Question 2

What does xanthochromia mean?

Answer 2

yellow discoloration of CSF

Question 3

What qualities of CSF from lumbar puncture might indicate subarachnoid hemorrhage?

Answer 3

elevated CSF RBCs, xanthochromia, increased OP

Question 4

What would be seen on muscle biopsy in polymyositis?

Answer 4

extensive necrosis of muscle fiber segments with macrophage and lymphocyte infiltration

Question 5

What would be seen on muscle biopsy in dermatomyositis?

Answer 5

perfascicular muscle fiber atrophy

Question 6

CSF sample from a patient with meningitis is most likely to show what?

Answer 6

elevated protein content, no RBCs, an elevated opening pressure, milky/xanthochromic fluid, elevated WBCs (PMNs and lymphocytes), low glucose

Question 7

CSF that is largely normal except for markedly high protein is commonly seen in__?

Answer 7

Guillain-Barre syndrome

protein may exceed 1 g

Question 8

What condition is indicated by CSF fluid with elevation of gamma globulin content?

Answer 8

MS

+ oligoclonal banding studies of the fluid

Question 9

What condition is indicated by extremely high CSF opening pressure?

Answer 9

pseudotumor cerebri

Question 10

What disease has a characteristic EEG with sharp, triphasic, and synchronous discharges?

Answer 10

prion

Question 11

How do you diagnose Friedreich ataxia?

Answer 11

genetic testing - GAA repeat sequence in frataxin gene

Question 12

What is polysomnography?

Answer 12

sleep study

Question 13

Creutzfedt-Jakob disease will show what on CSF analysis?

Answer 13

14-3-3 protein concentrations