The Cell & Cell Structure Flashcards

(122 cards)

1
Q

two main factors that cause HL

A

Infants may be born with hearing loss caused by a viral infection that was acquired during pregnancy - an environmental factor
At other times, the cause is genetic; the development of the auditory-vestibular system depends on sequential activation of multiple genes, problems with any one gene can cause a genetic hearing loss

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2
Q

How many genes need to be affected to cause a genetic HL

A

just one

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3
Q

something that happens later in life, after birth, environmental thing
meningitis - causes HL and can become deaf in one or both ears

A

Acquired HL

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4
Q

inherited it from parents and could be born with it or it could happen later in life
some cancer genes, but breast cancer is in older girls

A

genetic HL

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5
Q

why is HL complex?

A

because the process of hearing is complex

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6
Q

can HL be a combo of genetic and environmental factors?

A

YES
more susceptible to antiobiotics for example

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7
Q

How can understanding genetic causes of HL be important?

A

knowledge allows dr’s to inform families about chances of having children with HL and influences the way the HL is treated.
if person’s HL will get worse, sometimes predicted if the specific cause of it is known

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8
Q

syndromic condition

A

two or more systems are affected

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9
Q

nonsyndromic conditions

A

only one system is affected

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10
Q

is it common for kids to have genetic HL even if the parents do not?

A

YES
HL can be passed onto future generations

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11
Q

Why should we study cell biology in a genetics course in audiology?

A

The cell is the basic unit of structure and function in all organisms

Genes control the shape, size, and function of cells
The study of cell structure and function helps us understand how genetic disorders disrupt the cellular processes

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12
Q

two main types of cells

A

prokaryotic and eukaryotic cells

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13
Q

have a plasma membrane (cell wall) but do not have a membrane-bound nucleus or other membrane-bound organelles (little organs - structures within cells)

A

prokaryotic cells

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14
Q

little organs - structures within cells

A

membrane-bound organelles

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15
Q

typically unicellular cells
most bacteria are this

A

prokaryotic cells

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16
Q

DNA is found in a coiled loop (chromosome) floating in the cytoplasm

A

prokaryotic cell

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17
Q

posses both a plasma membrane and nuclear membrane along with other organelles

A

eukaryotic cells

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18
Q

nucleus has dna

A

eukaryotic cells

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19
Q

all large complex species including humans have these cells

A

eukaryotic cells

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20
Q

where are human chromosomes found?

A

in the nucleus

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21
Q

body

A

soma

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22
Q

cells that differentiate into tissues and organs the body

A

somatic cells

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23
Q

Cells from which a new organism can develop
egg and sperm

A

germ cells

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24
Q

everything but your sex cells
cannot build new life

A

somatic cells

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25
which cells can build a new life organisms develop from here
germ cells
26
what are cells formed from
molecules
27
The last common ancestor of life on earth was the closest thing to an autonomous biologic unit
cell
28
what do all cells use
same molecular building blocks Similar methods for storage Similar cell maintenance methods Similar methods for expression of genetic information Similar processes of energy metabolism Similar methods for molecular transport and cell signaling Similar processes for cell development and structure
29
how is genetic information expressed?
the way you look, walk, eye color, function etc is determined by genes
30
ow a gene shows up in the persona, how the gene manifests itself on the person
gene expression
31
expression of the gene that makes you function how you are
phenotype
32
how cells communicate with each other
cell signaling
33
how do cells help us understand why something went ary?
because at the cellular level, life is remarkably similar
34
the transfer of information from one cell to another
cell signaling
35
how do cells signal eachother?
by direct contact with eachother by release of substance (hormone or NT) from one cell that is taken up by another cell
36
why do we need cell signlaing?
important for cells to grow and work normally
37
How do cells interact
cell signaling
38
junction bw two cells
synapse
39
how do receptors on a receiving cel l work
shape of it and NT have to match, if it doesnt meat it, the signaling will not happen and whatever it is signaling is the changing in the cell and therefore will not happen
40
dynamic and active component of cells It prevents the free flow of molecules in and out of the cell It controls the exchange of materials between the external environment and the cell
plasma membrane
41
compartment with a watery interior that is separated from the external environment by a surface membrane (or wall)
plasma membrame
42
what is the plasma membrane composed of
a bilayer (2 layers) of phospholipid molecules
43
what is a phospholipid
A lipid containing a phosphate group in its molecule, e.g., lecithin
44
describe the structure of a phospholipid
consists of two hydrophobic fatty acid "tails" and a hydrophilic "head" consisting of a phosphate group
45
what is hydrophobic
water hating
46
what is hydrophilic
water loving
47
which part of the plasma membrane is hydrophobic?
tails
48
which part of the plasma membrane is hydrophilic
head
49
How do the two phospholipid layers orient
hydrophilic heads face toward the outer and inner surfaces of the plasma membrane hydrophobic tails are buried within the interior of the membrane
50
which part of the bilayer is exposed to the water
hydrophilic heads
51
which part of the bilayer is the plasma membrane
hydrophobic core
52
what are phospholipid membranes impermeable to
water (because they are water hateing) all ions all hydrophilic small molecules (how they control egressing and ingressing)
53
what do proteins in the membrane do?
some allow specific ions and small molecules to cross through others serve to attach cells to surrounding cells others give the cell its shape or allow its shape to change
54
why are proteins different shapes in the membrane/
different shapes are for different functions - they allow different ions to get through
55
what gives cells their molecular identity?
molecules on the plasma membrane
56
what are molecules cell properties important for
blood type determination of compatibility in organ transplants
57
what does the plasma membrane enclose
cytoplasm and organelles
58
complex mixture of molecules and structural components
cytoplasm
59
bilayer, made of phospholipid with hydrophobic and philic, multiple protein chains on it and these are responsible for given the cell the identity and controls what goes in and out of the cells (ions and molecules, etc.)
plasma membrane
60
gives the form and shape to the cells
cytoskeleton
61
system of microfilaments and microtubules that provide each cell strength and rigidity, helping each cell to maintain it’s characteristic shape
cytoskeleton
62
helps anchor cellular structures and is important for organizing the cell
cytoskeleton
63
cell motility is facilitated by
microfilaments
64
are fine, thread-like protein fibers, plays a role in cell motility & contractility.
microfilament
65
straight, hollow cylinders found throughout the cytoplasm of all eukaryotic cells functions, ranging from transport to structural support.
microtubules
66
Define the organelles Control their ionic composition so that it is different
organelles
67
Each has a unique set of proteins that enables it to carry out its function
organelle
68
specialized structures within the cytoplasm
organelles
69
Network of membranes that export protein from cells
ER
70
associated with ribosomes it functions in the synthesis and processing of proteins
Rough ER
71
Lacks ribosomes if functions in lipid synthesis (fat)
smooth ER
72
synthesize and process proteins
Ribosomes
73
factories that make your proteins
rough ER
74
makes lipids
smooth ER
75
made up of RNA and protein
ribosomes
76
serves as the primary site of biological protein synthesis
ribosomes
77
link amino acids together in the order specified by messenger RNA (mRNA) molecules
ribosomes
78
Flattened membrane sacs that receive proteins from the ER Proteins are further processed here before being forwarded to their final destination
golgi
79
Membrane-enclosed sacs that contain digestive enzymes They break down or recycle worn-out and obsolete cells parts
lysosomes
80
Largest organelle surrounded by 2 phospholipid bilayer membranes
mitochondria
81
Energy source of cells that produce most of the adenosine triphosphate (ATP) in eukaryotic cells
mitochondria
82
what is ATP
energy source that is used to drive most energy-requiring cellular processes
83
what were mitochondria originally
believed to originate as bacteria that took up residence in eukaryotic cells and over time became welcome collaborators
84
genetic mutations to antibiotics form where
mitochondria
85
still contain small genomes that encode essential proteins revealing their bacterial origins
mitochondria
86
cell organelle involved in energy transformation
mitochondria
87
contains our DNA
nucleus
88
Largest, most prominent of the membrane-bounded organelles which characterize eukaryotic cells
nucleus
89
Responsible for growth and reproduction of the cell
nucleus
90
Enclosed with a double membrane that allows direct communication between the nucleus and cytoplasm
nucleus
91
dense regions in the nucleus that synthesize ribosomes
nucleoli
92
Dark strands and clumps of chromatin (chromosomes) are seen throughout here
nucleus
93
Contains the cell’s genetic information (DNA) organized into genes that determines the shape, structure, and range of functions carried out by the cell
nucleus
94
where is genetic information contained?
chromatin that turns into chromosomes in the nucleus
95
complex of DNA and proteins that make up a chromosome is called
chromatin
96
Chromatin are organized into
chromosomes
97
rod-shaped microscopic structures carrying the genes that carry genetic information transmitted from generation to generation
chromosomes
98
As the cell prepares to divide, the chromatin condenses and coils to form _______
chromosomes
99
where do genes lie
on chromosomes
100
How do individual chromosomes take the form of two chromatids?
individual chromosomes connect at the centromere to create the X formation
101
consists of a single, double-stranded DNA molecule
chromosomes
102
consists of two DNA strands joined together by their centromere
chromatid
103
appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division Specifically, it is the region where the cell's spindle fibers attach.
centromere
104
short arm of chromosomes
p arm
105
long arm of chromosomes
q arm
106
explain the 46 chromosomes in humans
22 pairs of autosomes one pair (XX XY) are sex chromosomes
107
what would you see on chromosome for down syndrome?
extra chromosomes of 21
108
where chromatids join
centromere
109
Number of sets of chromosomes in a biological cell
ploidy
110
condition in which each chromosome is represented twice as a member of a homologous pair, one set from each parent
diploid
111
humans are always _____
diploid
112
One full set of chromosomes occurring in a mature germ cell or half the number of chromosomes (23) found in a normal somatic cell (22X or 22Y)
haploid
113
general appearance of somatic chromosomes
karyotype
114
identical
homologous
115
chromosome disorders are diff than single gene mutations
true
116
one gene on a chromosome that has gone ary, genetic mutation
single
117
an extra or a lack of chromosome, most are not compatible with life because you have taken a whole bunch of genes
chromosome mutation
118
how the gene will manifest, how you will look, function, behave, etc.
gene expression
119
Describes alleles present in a gene
genotype
120
genetic composition of an individual, i.e., the fundamental characteristic of an organism in terms of hereditary factors
genotype
121
Describes the expression of an allele combination present in a gene
phenotype
122
The manifest characteristics of an organism collectively, i.e., traits that result from both its hereditary and its environment – nature and nurture
phenotype