The Extraembryonic membranes Flashcards

(170 cards)

1
Q

The Extraembryonic Membranes

________: encompasses yolk
amnion: enclosing the amniotic cavity
allantois: outgrowth of hindgut

A

yolk sac

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2
Q

The Extraembryonic Membranes

yolk sac: encompasses yolk
_______: enclosing the amniotic cavity
allantois: outgrowth of hindgut

A

amnion

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3
Q

The Extraembryonic Membranes

yolk sac: encompasses yolk
amnion: enclosing the amniotic cavity
________: outgrowth of hindgut

A

allantois

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4
Q

The Extraembryonic Membranes

yolk sac: encompasses yolk
amnion: enclosing the amniotic cavity
allantois: outgrowth of _______

A

hindgut

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5
Q

The Extraembryonic membranes

  • _________: chorio-allantoic membrane
  • can be used as a model to assay angiogenesis: ability of a substanceto develop blood cells
  • growing stages
  • head fold and tail fold: forming the amniotic cavity
A

angiogenesis

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6
Q

The Extraembryonic membranes

  • angiogenesis: ___________ membrane
  • can be used as a model to assay angiogenesis: ability of a substanceto develop blood cells
  • growing stages
  • head fold and tail fold: forming the amniotic cavity
A

chorio-allantoic

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7
Q

The Extraembryonic membranes

  • angiogenesis: chorio-allantoic membrane
  • can be used as a model to ______ angiogenesis: ability of a substance to develop blood cells
  • growing stages
  • head fold and tail fold: forming the amniotic cavity
A

assay

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8
Q

The Extraembryonic membranes

  • angiogenesis: chorio-allantoic membrane
  • can be used as a model to assay angiogenesis: ability of a substance to develop _______ cells
  • growing stages
  • head fold and tail fold: forming the amniotic cavity
A

blood

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9
Q

The Extraembryonic membranes

  • angiogenesis: chorio-allantoic membrane
  • can be used as a model to assay angiogenesis: ability of a substanceto develop blood cells
  • growing stages
  • head fold and tail fold: forming the ______ ______
A

amniotic cavity

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10
Q

Human Extraembryonic Membranes

  • formation of each is ______
  • blastocyst: inner cell mass and trophoblast
  • trophoblast: equivalent of chorion

No head folding
Formation is Independent of amnion

A

different

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11
Q

Human Extraembryonic Membranes

  • formation of each is different
  • ________: inner cell mass and trophoblast
  • trophoblast: equivalent of chorion

No head folding
Formation is Independent of amnion

A

blastocyst

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12
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: ______ _____ _____and trophoblast
  • trophoblast: equivalent of chorion

No head folding
Formation is Independent of amnion

A

inner cell mass

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13
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and _______
  • trophoblast: equivalent of chorion

No head folding
Formation is Independent of amnion

A

trophoblast

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14
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and trophoblast
  • ________: equivalent of chorion

No head folding
Formation is Independent of amnion

A

trophoblast

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15
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and trophoblast
  • trophoblast: equivalent of ______

No head folding
Formation is Independent of amnion

A

chorion

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16
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and trophoblast
  • trophoblast: equivalent of chorion

_____ head folding
Formation is Independent of amnion

A

No

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17
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and trophoblast
  • trophoblast: equivalent of chorion

No head folding
Formation is ________ of amnion

A

independent

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18
Q

Human Extraembryonic Membranes

  • formation of each is different
  • blastocyst: inner cell mass and trophoblast
  • trophoblast: equivalent of chorion

No head folding
Formation is Independent of _______

A

amnion

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19
Q

Human Extraembryonic Membranes

  • ______: from inner cell mass
    Magkakaroon ng butas; fuse to become amniotic cavity
  • natitira: magfoform ng yolk sac
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

amnion

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20
Q

Human Extraembryonic Membranes

  • amnion: from _____ ____ ______
    Magkakaroon ng butas; fuse to become amniotic cavity
  • natitira: magfoform ng yolk sac
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

inner cell mass

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21
Q

Human Extraembryonic Membranes

  • amnion: from inner cell mass
    Magkakaroon ng _____; fuse to become amniotic cavity
  • natitira: magfoform ng yolk sac
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

butas

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22
Q

Human Extraembryonic Membranes

  • amnion: from inner cell mass
    Magkakaroon ng butas; ______ to become amniotic cavity
  • natitira: magfoform ng yolk sac
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

fuse

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23
Q

Human Extraembryonic Membranes

  • amnion: from inner cell mass
    Magkakaroon ng butas; fuse to become _____ ______
  • natitira: magfoform ng yolk sac
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

amniotic cavity

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24
Q

Human Extraembryonic Membranes

  • amnion: from inner cell mass
    Magkakaroon ng butas; fuse to become amniotic cavity
  • natitira: magfoform ng _____ ____
    Unlike in avian (endodermal cells growing around the yolk)
  • rest of cells: will divide to form epiblast and hypoblast
    -formation of primitive streak
  • posterior part of gut: evagination: allantois
A

yolk sac

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25
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in _____ (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: allantois
avian
26
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (_______ ____ growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: allantois
endodermal cells
27
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the ____) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: allantois
yolk
28
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - ______ __ _____: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: allantois
rest of cells
29
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will ______ to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: allantois
divide
30
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form ______ and ______ -formation of primitive streak - posterior part of gut: evagination: allantois
epiblast, hypoblast
31
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of ______ _______ - posterior part of gut: evagination: allantois
primitive streak
32
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - ______ part of gut: evagination: allantois
posterior
33
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of ___: evagination: allantois
gut
34
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: ______: allantois
evagination
35
Human Extraembryonic Membranes - amnion: from inner cell mass Magkakaroon ng butas; fuse to become amniotic cavity - natitira: magfoform ng yolk sac Unlike in avian (endodermal cells growing around the yolk) - rest of cells: will divide to form epiblast and hypoblast -formation of primitive streak - posterior part of gut: evagination: _____
allantois
36
Mammalian Extraembryonic Membranes - as it rolls down the _____ - hatches from zona pellucida - buries itself with inner cell mass on one side, facing - the side where the ICM is growing: the one responsible to secrete enzymes to cut itself to the wall of uterus - chorin growing into the substance of the wall
uterus
37
Mammalian Extraembryonic Membranes - as it rolls down the uterus - hatches from _____ ______ - buries itself with inner cell mass on one side, facing - the side where the ICM is growing: the one responsible to secrete enzymes to cut itself to the wall of uterus - chorin growing into the substance of the wall
zona pellucida
38
Mammalian Extraembryonic Membranes - as it rolls down the uterus - hatches from zona pellucida - buries itself with _____ ___ _____ on one side, facing - the side where the ICM is growing: the one responsible to secrete enzymes to cut itself to the wall of uterus - chorin growing into the substance of the wall
inner cell mass
39
Mammalian Extraembryonic Membranes - as it rolls down the uterus - hatches from zona pellucida - buries itself with inner cell mass on one side, facing - the side where the ICM is growing: the one responsible to secrete ______ to cut itself to the wall of uterus - chorin growing into the substance of the wall
enzymes
40
Mammalian Extraembryonic Membranes - as it rolls down the uterus - hatches from zona pellucida - buries itself with inner cell mass on one side, facing - the side where the ICM is growing: the one responsible to secrete enzymes to cut itself to the wall of uterus - _______ growing into the substance of the wall
chorion
41
Mammalian Extraembryonic Membranes - _____ becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
chorion
42
Mammalian Extraembryonic Membranes - chorion becomes divided into two: ________ : the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
cytotrophoblast
43
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the ______ walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
cellular
44
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are _____ and _____ _______ syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
clear, well differentiated
45
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated _________ : > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
syncitiotrophoblast
46
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are ___ _______from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
not differentiated
47
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a ____ ______ > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
cell membrane
48
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to ___ ______ from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo Blood: maternal contribution
cut itself
49
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the ______, bathe the blood vessels that come from the embryo Blood: maternal contribution
mother
50
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the ______ ______ that come from the embryo Blood: maternal contribution
blood vessels
51
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the ______ Blood: maternal contribution
embryo
52
Mammalian Extraembryonic Membranes - chorion becomes divided into two: cytotrophoblast: the cellular walls > cells are clear and well differentiated syncitiotrophoblast: > cells are not differentiated from each other by a cell membrane > secreting substances to cut itself from the wall - red: spaces: blood from the mother, bathe the blood vessels that come from the embryo ______ : maternal contribution
Blood
53
Mammalian Extraembryonic Membranes - the whole of the _____ is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
embryo
54
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the _____ - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
villi
55
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi _______ only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
concentrate
56
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - ______ ____ forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
umbilical stalk
57
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will ______ -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
disappear
58
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear - _______ of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
capsule
59
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: ______ ______: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to placenta
chorion fondosum
60
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of _____ chorion laeve: chorion is smooth - fetal contribution to placenta
villi
61
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi ______ ______: chorion is smooth - fetal contribution to placenta
chorion laeve
62
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is _______ - fetal contribution to placenta
smooth
63
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - ______ contribution to placenta
fetal
64
Mammalian Extraembryonic Membranes - the whole of the embryo is covered by the villi - villi concentrate only where it started in the beginning - umbilical stalk forms - all the villi will disappear -capsule of embryo is divided into: chorion fondosum: has a lot of villi chorion laeve: chorion is smooth - fetal contribution to ________
placenta
65
Mammalian Extraembryonic Membranes maternal contribution also divided into two: ______ _____ desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
desidua basalis
66
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis ________ ________ Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
desidua capsulares
67
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: _______ _______ - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
desidua parietalis
68
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - _______ capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
dumidikit
69
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - ______ _______membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
chorio-allantoic
70
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane _______ : very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
Allantois
71
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very ________ - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
vascularized
72
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most ______ part of allantois is useful that will become the u. bladder -villi of chorion is made up from the allantois
proximal
73
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the _______ ______ -villi of chorion is made up from the allantois
urinary bladder
74
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder - ______ of chorion is made up from the allantois
villi
75
Mammalian Extraembryonic Membranes maternal contribution also divided into two: desidua basalis desidua capsulares Next to leave - other parts of uterine wall where the baby is not growing: desidua parietalis - dumidikit capsulares with parietalis: kapag naggrow na ung baby sa buong parts - chorio-allantoic membrane Allantois: very vascularized - here: only most proximal part of allantois is useful that will become the u. bladder -villi of chorion is made up from the _______
allantois
76
Mammalian Extraembryonic Membranes ______ ________: in chick: corresponds to chorio-allantois - blood vessels very intricate, forming a network - every time the heart beats, cavity is filled up with blood
umbilical vessels
77
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to ______ ________ - blood vessels very intricate, forming a network - every time the heart beats, cavity is filled up with blood
chorio-allantois
78
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to chorio-allantois - blood vessels very _______, forming a network - every time the heart beats, cavity is filled up with blood
intricate
79
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to chorio-allantois - blood vessels very intricate, forming a ______ - every time the heart beats, cavity is filled up with blood
network
80
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to chorio-allantois - blood vessels very intricate, forming a network - every time the heart ______, cavity is filled up with blood
beats
81
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to chorio-allantois - blood vessels very intricate, forming a network - every time the heart beats, _____ is filled up with blood
cavity
82
Mammalian Extraembryonic Membranes umbilical vessels: in chick: corresponds to chorio-allantois - blood vessels very intricate, forming a network - every time the heart beats, cavity is filled up with _____
blood
83
Mammalian Extraembryonic membranes - different types of ______ - maliit na bukol²: chorionic villi - sow: sobrang daming villi - bitch: just around it - represent chorionic blood vessels
placentation
84
Mammalian Extraembryonic membranes - different types of placentation - maliit na bukol²: _______ ____ - sow: sobrang daming villi - bitch: just around it - represent chorionic blood vessels
chorionic villi
85
Mammalian Extraembryonic membranes - different types of placentation - maliit na bukol²: chorionic villi - ____ : sobrang daming villi - bitch: just around it - represent chorionic blood vessels
sow
86
Mammalian Extraembryonic membranes - different types of placentation - maliit na bukol²: chorionic villi - sow: sobrang daming villi - ____ : just around it - represent chorionic blood vessels
bitch
87
Mammalian Extraembryonic membranes - different types of placentation - maliit na bukol²: chorionic villi - sow: sobrang daming villi - bitch: just around it - represent _______ blood vessels
chorionic
88
Mammalian Extraembryonic Membranes - represents from across organisms: closeness of the relationship of the contributions from the mother and _____ - gradual increase in closeness - maternal wall of uterus: maternal side - chorionic villi: fetal side
fetus
89
Mammalian Extraembryonic Membranes - represents from across organisms: closeness of the relationship of the contributions from the mother and fetus - _____ increase in closeness - maternal wall of uterus: maternal side - chorionic villi: fetal side
gradual
90
Mammalian Extraembryonic Membranes - represents from across organisms: closeness of the relationship of the contributions from the mother and fetus - gradual increase in closeness - maternal wall of _____: maternal side - chorionic villi: fetal side
uterus
91
Mammalian Extraembryonic Membranes - represents from across organisms: closeness of the relationship of the contributions from the mother and fetus - gradual increase in closeness - maternal wall of uterus: maternal side - chorionic villi: ______ _____
fetal side
92
Mammalian Extraembryonic Membranes - represents from across organisms: closeness of the relationship of the contributions from the mother and fetus - gradual increase in closeness - maternal wall of uterus: maternal side - _______ _____: fetal side
chorionic villi
93
Extraembryonic Membranes ___________ - all intact ang epithelium and blood vessels and connective tissues - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of blood
Epitheliochoral
94
Extraembryonic Membranes Epitheliochoral - ___ ______ ang epithelium and blood vessels and connective tissues - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of blood
all intact
95
Extraembryonic Membranes Epitheliochoral - all intact ang ______ and blood vessels and connective tissues - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of blood
epithelium
96
Extraembryonic Membranes Epitheliochoral - all intact ang epithelium and _____ _____ and connective tissues - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of blood
blood vessels
97
Extraembryonic Membranes Epitheliochoral - all intact ang epithelium and blood vessels and _______ ____ - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of blood
connective tissues
98
Extraembryonic Membranes Epitheliochoral - all intact ang epithelium and blood vessels and connective tissues - Baby slips out of maternal _______ - No radical change to mother or baby - No great loss of blood
uterus
99
Extraembryonic Membranes Epitheliochoral - all intact ang epithelium and blood vessels and connective tissues - Baby slips out of maternal uterus - No ______ change to mother or baby - No great loss of blood
radical
100
Extraembryonic Membranes Epitheliochoral - all intact ang epithelium and blood vessels and connective tissues - Baby slips out of maternal uterus - No radical change to mother or baby - No great loss of _____
blood
101
Extraembryonic Membranes ____________ - Maternal blood vessel still surrounded by connective tissue - But there is a common epithelial lining
endotheliochoral
102
Extraembryonic Membranes Endotheliochoral - _______ blood vessel still surrounded by connective tissue - But there is a common epithelial lining
maternal
103
Extraembryonic Membranes Endotheliochoral - Maternal blood vessel still surrounded by _______ _____ - But there is a common epithelial lining
connective tissue
104
Extraembryonic Membranes Endotheliochoral - Maternal blood vessel still surrounded by connective tissue - But there is a common ________ _____
epithelial lining
105
Extraembryonic Membranes ________ - Blood vessel wala nang wall at connective tissue - Blood vessel: mas madali makakuha ng nutrients at maka-empty ng wastes
Hemochorial
106
Extraembryonic Membranes Hemochorial - Blood vessel wala nang ____ at __________ - Blood vessel: mas madali makakuha ng nutrients at maka-empty ng wastes
wall, connective tissue
107
Extraembryonic Membranes Hemochorial - _____ ______ wala nang wall at connective tissue - Blood vessel: mas madali makakuha ng nutrients at maka-empty ng wastes
blood vessel
108
Extraembryonic Membranes Hemochorial - Blood vessel wala nang wall at connective tissue - ______ ______: mas madali makakuha ng nutrients at maka-empty ng wastes
blood vessel
109
Extraembryonic Membranes Hemochorial - Blood vessel wala nang wall at connective tissue - Blood vessel: mas madali makakuha ng _______ at maka-empty ng wastes
nutrients
110
Extraembryonic Membranes Hemochorial - Blood vessel wala nang wall at connective tissue - Blood vessel: mas madali makakuha ng nutrients at maka-empty ng _______
wastes
111
Extraembryonic Membranes ________ - Blood vessel na lang ang nagseseparate - Closest
Hemoendothelial
112
Extraembryonic Membranes Hemoendothelial - ______ _____ na lang ang nagseseparate - Closest
blood vessel
113
Extraembryonic Membranes Hemoendothelial - Blood vessel na lang ang nagseseparate - ______
closest
114
Functions of Placenta - ________: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
Nutritional
115
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has ______ property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
angiogenic
116
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - _______: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
Endocrine
117
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to ______ the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
retain
118
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also _______ mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
accelerate
119
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - ___________ : block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
Immunological
120
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the ______ against the developing fetus. - Recent studies suggest that the placenta uses several mechanisms to block the mother's immune response.
mother
121
Functions of Placenta - Nutritional: provides sustenance to developing embryo - Has angiogenic property: causes the formation of blood vessel supply to where the fetus is growing - Endocrine: provide hormones that enable the uterus to retain the pregnancy and also accelerate mammary gland development - Immunological: block the potential immune response of the mother against the developing fetus. - Recent studies suggest that the _______ uses several mechanisms to block the mother's immune response.
placenta
122
Antigenic Properties of the Embryo and the Placenta - On its ______ ____, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
surface cells
123
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits ____ ______ that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
HLA proteins
124
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - _____ ______ and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
Fetal tissue
125
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the _______ (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
placenta
126
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (________ and _______ of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
syncytiotrophoblast, cytotrophoblast
127
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in _____ ______ to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
direct contact
128
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the _______ organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
maternal
129
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce __ _____ ______ (HLA- A, -B, -C complexes = main complexes of the histocompatibility)
no tissue antigens
130
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (______ ___ ___complexes = main complexes of the histocompatibility)
HLA -A, -B, -C
131
Antigenic Properties of the Embryo and the Placenta - On its surface cells, an embryo exhibits HLA proteins that differ from those of the mother - Fetal tissue and especially that of the placenta (syncytiotrophoblast and cytotrophoblast of the villi) in direct contact to the maternal organism produce no tissue antigens (HLA- A, -B, -C complexes = main complexes of the __________)
histocompatibility
132
Antigenic Properties of the Embryo and the Placenta - Nevertheless,_____ antigens, which do not distinguish between individuals, occurs through the extravillous cytothrophoblast. The HLA -G antigen takes over anti-viral and immunosuppressive functions as well as non-immunologic tasks.
HLA -G
133
Antigenic Properties of the Embryo and the Placenta - Nevertheless, HLA- G antigens, which do not distinguish between individuals, occurs through the ________ cytothrophoblast. The HLA -G antigen takes over anti-viral and immunosuppressive functions as well as non-immunologic tasks.
extravillous
134
Antigenic Properties of the Embryo and the Placenta - Nevertheless, HLA- G antigens, which do not distinguish between individuals, occurs through the extravillous cytothrophoblast. The HLA -G antigen ______ _____ anti-viral and immunosuppressive functions as well as non-immunologic tasks.
takes over
135
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some _______ hormones (e.g., progesterone) have an immunosuppressive effect on the lymphocytes of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the PBIF protein (Progesterone Induced Blocking Factor)
steroid
136
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., ________) have an immunosuppressive effect on the lymphocytes of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the PBIF protein (Progesterone Induced Blocking Factor)
progesterone
137
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., progesterone) have an _____________ _____ on the lymphocytes of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the PBIF protein (Progesterone Induced Blocking Factor)
immunosuppressive effect
138
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., progesterone) have an immunosuppressive effect on the _________ of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the PBIF protein (Progesterone Induced Blocking Factor)
lymphocytes
139
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., progesterone) have an immunosuppressive effect on the lymphocytes of the pregnant woman. _________ seems to play an important immunosuppressive role that is mediated by the PBIF protein (Progesterone Induced Blocking Factor)
Progesterone
140
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., progesterone) have an immunosuppressive effect on the lymphocytes of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the ____ _____ (Progesterone Induced Blocking Factor)
PBIF protein
141
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - Some steroid hormones (e.g., progesterone) have an immunosuppressive effect on the lymphocytes of the pregnant woman. Progesterone seems to play an important immunosuppressive role that is mediated by the PBIF protein (_____ ______ ______ _____)
Progesterone Induced Blocking Factor
142
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The _______ ________ control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
cytotoxic T-lymphocytes
143
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the ____ _______ of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
cell population
144
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through _______, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
cytolysis
145
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "____ _____") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
not self
146
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("___, _____ _______"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
self, but modified
147
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). _______ cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
trophoblast
148
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be _______ as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
destroyed
149
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as ______ ______. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
foreign tissue
150
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its _____ at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
binding
151
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a ___ (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
HLA
152
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (_____ ______) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
identity marking
153
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells __ ___ ______classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
do not produce
154
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce ______ ___, they cannot be recognized by the T-lymphocytes as foreign tissue and so escape destruction.
classical HLA
155
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the _________ as foreign tissue and so escape destruction.
T-lymphocytes
156
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as ______ tissue and so escape destruction.
foreign
157
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The cytotoxic T-lymphocytes control the cell population of the organism and, through cytolysis, destroy foreign cells (foreign to the body, "not self") or those cells of the organism that present a foreign antigen ("self, but modified"). Trophoblast cells would therefore have to be destroyed as foreign tissue. Since the recognition of an antigen presupposes its binding at a HLA (identity marking) protein and since trophoblast cells do not produce classical HLA, they cannot be recognized by the T-lymphocytes as foreign tissue and so _____ destruction.
escape
158
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The ____ (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
NK cells
159
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (_____ ______, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
Natural Killer
160
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, __ __ ___ ___ ________) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
non-B-non-T-lymphocytes
161
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) ____ cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
attack
162
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that __ ___ ____ clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
do not possess
163
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess _____ ______ markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
classical HLA
164
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., _______ cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
trophoblast
165
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the _____ marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
HLA-G
166
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, ______ their cytolytic activity. The fetus is thus protected from the maternal immune defense system.
inhibiting
167
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their _______ activity. The fetus is thus protected from the maternal immune defense system.
cytolytic
168
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The _____ is thus protected from the maternal immune defense system.
fetus
169
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus _______ from the maternal immune defense system.
protected
170
Antigenic properties of the Embryo and the Placenta - placenta blocks cytotoxic maternal cell effects by secreting various factors: - The NK cells (Natural Killer, non-B-non-T-lymphocytes) attack cells that do not possess clasical HLA markers, e.g., trophoblast cells. NK cells, though, are outfitted with a system that detects the HLA-G marker on trophoblast cells, inhibiting their cytolytic activity. The fetus is thus protected from the _______ immune defense system.
maternal