the genetics project Flashcards
(38 cards)
hemophilia and colorblindness are
sexlinked genes
in a karyotype ____ are labelled with #s and ___ are labeled with lettes
autosomes and sex chromsomes
karyotypes tell us 3 things
1) species (different species have different amounts of chromosomes )
2) gender
3) chromsomal disorders
chromosomal disorder types
1-translocation
2 trisomy
3 monosomy
whats a translocation
when part of a chromosome breaks off and attached to another
2n
of chromsomes in somatic cells
n
of chromsomes in gametes
in a karyotype, what are the dark regions of a chromsom
heterochromatin- the non expressed genes so tightly coiled that mRNA can do anything and they aren’t ex spressed
in a karyotype, what are the lighter regions of a chromosome
euchromatin-the expressed genes.
13 trisomy
pataus syndrome
21 trisomy
down syndrome
XXY
klinefelter
XO
turners syndrome
XXX, XXXX, XXXXX, XXXY, XXXXY
multiple sex chromsomes
D-G translocation
fragment beaks off D and goes to G
in a pedigree a double line =
consanguinous marriage (marriage within a family)
in a pedigree, a diamond is
someone whose sex is not known
what if the baby of a RH - mom is Rh +
doctors give her chemicals to ssuppress the anitgens-they protect the +fetal cells
what happens when antigen and antibodies react
the antibodies clump the antigens together and make blood clots- if a red blood cell is broken, it can release toxic reactions
who won nobel prize for resesarch on blood groups
landsteiner
agglunates def
cells clot together
how does blood typing work
mix blood with A B RH antigens and wichever clumps, is the type
what is an autologous blood donation
you give blood before surgery, then use your own blood duing surgery and after
duffy antigens and malaria
duffy negative dont get a lot of malaria parasites
