The role of endogenous hormones in muscle hypertrophy

Question 1

According to Vingren et al 2010 - what is the major promoter of muscle growth and strength in RT for men

Answer 1

Testosterone
“The acute endocrine response to heavy resistance exercise includes secretion of various catabolic and anabolic hormones, including test.”

Question 2

What are the ACSM recommendations for RT?

Answer 2

• large before small muscles
• multi-joint before single-joint
• High before low-intensity exercises

Question 3

What did West et al 2010 expect to find in a study training biceps alone vs biceps + legs

Answer 3

Exercises large muscles first to increase test and GH levels. Biceps training in an environment where muscle was bathed in these hormones.
- Assume PS would be higher in biceps + legs group

Question 4

What did West et al 2010 find in a study training biceps alone vs biceps + legs

Answer 4

Despite bicep being in and increased hormone concentration in biceps + legs group, PS rates didn’t vary between groups. Only acutely.

Question 5

What is the relationship between exercise-induced changes in MPS between men and women, in relation to test levels?

Answer 5

Women have 10-15 fold lower test conc than men, do not experience sig. elevations in post-exercise test when compared with men.
However, exercise-induced changes in MPS are = in men and women, despite ~45 fold difference in exercise induced testosteronemia.