Things I always forget Flashcards

1
Q

High Frequency oscillatory ventilation

A

HFOV - very high RR, very small tidal volumes

*helps lower risk of distention in ARDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Extracorpeal membrane oxygenation

A

ECMO - supports hypoxemia without the potentially injurious ventilator setting sometimes needed in severe ARDS

“a treatment that uses a pump to circulate blood through an artificial lung back into the bloodstream… provides heart-lung bypass support outside of the body”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Viruses that are most associated with acute cough

A

influenza A and B, rhinovirus, adenovirus, echovirus, RSV, parainfluenza, coronavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Side effects of antitussives

A

confusion, nausea, constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Three main causes of chronic cough in non smokers, normal CXR, with no ACE I

A
  • GERD
  • Asthma
  • Upper Airway Cough Syndrome (UACS)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Massive hemoptysis causes death via

A

asphyxiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

MRC Dyspnea Scale

A
  1. no trouble except with strenuous exercise
  2. SOB when hurrying at level or walking up slight hill
  3. walks slower than most on level, stops 1 mile, or 15 min
  4. stops for breath after walking 100 yards or few min
  5. too breathless to leave house or SOB when undressing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do patients describe dyspnea with:

a. Asthma
b. HF

A

a. chest tightness

b. air hunger/suffocating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Risk factors of head/neck cancers

A
  • alcohol
  • tobacco
  • EBV
  • HPV
  • marijuana
  • pollutant exposure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sx of cancer of nasopharynx

A

epistaxis, otis media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tumor stagins

A

T1 - less then or equal to 2cm
T2 - greater then 2cm but less then 4cm
T3 - greater than 4cm
T4A - invasion of skin, mandible, ear canal, fascial n.
T4B - invasion of skull, pterygoid plates, encases carotid a.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When should you use sputum cytology to check for lung cancer?

A

pts with poor pulmonary function who cannot tolerate invasive procedures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If there is malignancy in non small cell lung cancer, what can’t you do?

A

surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What two features characterize benign pulmonary nodules?

A
  1. no growth in 2 years
  2. calcification in a diffuse, central, or laminar pattern

*malignant nodules are greater then 2 cm, have speculated edges, located in upper lobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Gold Criteria for COPD

A
  • I Mild: FEV1/FVC < 70%; FEV1 > 80%
  • II Moderate: FEV1/FVC <70%; 50 < FEV1 < 80%
  • III Severe: FEV1/FVC <70%; 30% < FEV1 < 50%
  • IV Very severe: FEV1/FVC <70%; FEV1 < 30% or FEV1 < 50% with chronic respiratory failure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When do you give oxygen therapy to someone with COPD?

A

arterial PO2 = 55 mmHG

or

oxygen saturation = 88% with or without hypercapnia

or

arterial PO2 = 59 mmHG or oxygen saturation = 89% if they have pulmonary HTN, cor pulmonale, edema due to RHF, or hematocrit >55%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Drugs that cause Parenchymal lung disease

A
  • amiodarone
  • methotrexate
  • nitrofurantoin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

many patients with severe or chronic DPLD develop what?

A

pulmonary HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is needed to diagnosis of OSA?

A

polysomnography (PSG)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Leading causes of pleural effusions

A

HF, pneumonia, cancer

  • transudative: suggests HF
  • exudative: suggests cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

CURB-65

A

Confusion
Urea nitrogen >19.6 mg/dL
Respiration rate >/= 30
BP <90 mmHG or <60 mmHg and 65 or older

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

PH can only be confirmed via

A

right heart catheterization or direct measurement of mean pulmonary artery pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When is IGRA preferred?

A

when pts have gotten the BCG vaccination or those that are unlikely to return for TST interpretation

  • for kids 5 and younger, use TST over IGRA
  • neither test can distinguish b/t latent or active TB
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Triad of fat embolism

A

hypoxemia, neuro changes, petechial rash

*onset 24-48 hrs after event

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
How long should you overlap warfarin with heparin? how long should DVT pts be treated?
5 days 3 months
26
Only a normal what can exclude PE?
V/Q *tests for PE dx: contrast enhanced CT or ventilation - perfusion (V/Q) scanning
27
What HF sx can venous insufficiency of legs/varicose veins provide?
edema (not JVD or other HF sx)
28
HFrEF vs. HFpEF
a. systolic, S3, PND, DOE, orthopnea, EF < 40% b. diastolic, stiff ventricles, SOB, DOE, pulmonary edema ; associated with myocardial fibrosis, amyloidosis, acute ischemia, constrictive pericarditis, restrictive cardiomyopathy
29
High output vs. Low output HF
a. EFr but CO inc (prego, hyperthyroid, anemia...) | b. ischemic HD, dilated cardiomyopathy, pericardial dx
30
What causes MCD?
idiopathic 2 to Hodgkin's lymphoma
31
What causes FSGS?
idiopathic 2 to HIV, sickle cell dx, heroin, obesity, interferon tx, congenital malformations IF can have IgM, C3, C1
32
What causes membranous nephropathy?
1 with ABs to phospholipase A2 Receptor 2 to infections, SLE, Drugs (NSAIDs), solid tumors
33
What HS rxn is APSGN?
III *has dec C3 due to consumption
34
1. Subepi deposits | 2. sub endo deposits
1. acute GN | 2. lupus nephritis, MPGN
35
What pattern describes APSGN?
diffuse proliferative GN
36
Type II RPGN
IgA, lupus, hence schonlein Purpura
37
What does HLA DRB1 mean? HLA DQA1?
a. might get good pasture syndrome | b. might get membranous nephropathy
38
normal urinary protein levels
less then 150mg in 24 hrs
39
do corticosteroids and immunosuppressive treatment help with MGN?
nope
40
What do you see on IF in the following: a. APSGN b. Goodpasture c. MGN d. MCD e. MPGN Type I f. MPGN Type II g. IgA neuropathy h. FSGS
a. granular IgG, C3 in GBM and mesangium b. linear IgG, C3 c. granular IgG, C3 d. negative e. IgG, C3 (C1q, C4) f. IgG, C3 (C1q, C4) g. IgA (IgG, IgM, C3 in mesangium) h. IgM, C3
41
What can progress to chronic GN?
``` Crescentic GN (90) FSGS (50-80) MPGN (50) MGN (30-50) IgAN (30-50) Poststrep GN (1-2) ```
42
What is Acute Tubular Injury?
- damage from toxins or ischemia | - 3 stages (initiation, maintenance, recovery)
43
diffuse cortical necrosis
coagulative necrosis and both glomerulus and tubules (cortex is pale due to ischemic necrosis) *obstetric crisis, septic shock, surgery
44
What causes thickened GBM and increased mesangial matrix in DM nephropathy?
metabolic defect linked to hyperglycemia
45
Papillary Necrosis: a. DM b. Analgesics
a. pale, gray | b. red-brown
46
Xanthogranulomatous pyelonephritis is associated with what often?
proteus infection
47
Tubulointerstitial nephropathy
- azotemia + inability to concentrate urine - due to drug toxins - eosinophilia, fever, interstitial renal parenchymal infiltrates - one type is analgesic nephropathy (can show pap nec)
48
Benign nephrosclerosis is not usually associated with renal insufficiency except:
- AAs - superimposition of severe HTN - diabetic nephroapthy
49
Hemolytic Uremic Syndrome vs. Thrombotic Thrombocytopenia Purpura
HUS - normal ADAM, endo injury and activation, intravascular thrombosis; shiva like toxin TTP - abnormal ADAM, platelet activation and aggregation; NEURO INVOLVEMENT, fever, thrombocytopenia, renal failure, microangiopathic hemolytic anemia
50
Atypical HUS
1. inherited mutations of proteins that regular complement 2. multiple acquired cause of endo injury 3. antiphospholipid syndrome, pregnancy, sclerosis, malignant HTN, chemo...
51
TTP is more common in?
females; over 40
52
Most common source of embolus that causes renal infarction
mural emboli from LV
53
Sickle cell nephropathy
- patchy papillary necrosis - hematuria, hyposthenuria (general) - proteinuria (some)
54
Killip Classification of MI
I - absence of rales and S3 II - rales that don't clear with coughing over 1/3 or less of lung fields; S3 III - rales that don't clear with cough over more than 1/3 IV - cariogenic shock
55
Whens should pts. with an MI be given aspirin?
right away; even if fibrinolytic meds have already been given *if aspirin allergy --> P2Y12 inhibitor (-grel) though both should be give for preferably 1 year
56
What pts can be harmed by thrombolysis?
NSTEMI
57
Pts undergoing primary PCI should get what two drugs
glycoprotein IIb/IIIa inhibitors (abciximab) and heparin
58
Absolute CIs to Fibrinolytic Therapy
1. previous hemorrhagic stroke (or other strokes within 1 yr) 2. Intracranial neoplasm 3. Recent heard trauma (even minor trauma) 4. Active internal bleeding 5. Suspected Aortic Dissection
59
Nitrates should be avoided in pts who received PDE5 inhibitors in past ___ hours?
24
60
What meds do you discharge your pt on?
- aspirin | - P2Y12 inhibitor (if they received coronary stent)
61
Post infarction ischemia is more common following what MI?
NSTEMI
62
If sinus tachycardia is due to hemodynamic compromise, what is a CI?
beta blockers
63
Most pts with cariogenic shock have what dysfunction?
Moderate tos evere LV systolic dysfunction
64
What is the most appropriate vasopressor for cardiogenic hypotension?
dopamine
65
What is used for pts with symptomatic post infarction supra ventricular arrhythmias?
amiodarone
66
If you want a CABG, but you're on clopidogrel or ticagrelor, how long do you need to be off them before the surgery? prasurgrel?
a. 5 days | b. 7 days
67
What type of shock do burns cause?
hypovolemic shock
68
What qualifies SIRS?
1. temp above 100.4F or lower than 96.8 2. HR > 90 3. RR > 20 or PaCO2 less than 32 mmHG 4. abnormal WBC *when source of infection is found, it gets labeled as sepsis
69
Hypovolemic shock vs. Cardiogenic shock a. Contractility b. Ventricle size
a. H - preserved C - decreased b. H - small C - dilated/full
70
In shock, vasopressors or inotropic agents are administered only after what?
adequate fluid resuscitation
71
What are non osmotic stimuli for ADH release?
nausea, hypoxia, pain, medications
72
Drugs associated with SIADH
- antidepressants - anticonvulsants - anipsychotics - anti cancer (Cyclophosphamide) - opiates - MDMA (ecstasy)
73
What is Transtubular potassium gradient?
an invalid test you should not order *doesn't actually dx hyper K
74
What does sustained handgrip do to MVP? HCM?
a. increases intensity b. decreases intensity *both are intensified by valsalva and standing