Threadgill

Question 1

What is meant by the term antimetabolite?

Answer 1

Inhibitor of a key metabolic pathway usually one involved in the biosynthesis of DNA

Question 2

What are the four main groups of antimetabolite drugs used in the chemotherapy of cancer?

Answer 2

Folate ‘antagonists’
Pyrimidine ‘antagonists’
Purine ‘antagonists’
Sugar modified nucelosides