Thyroid Disorders Flashcards
(29 cards)
Butterfly shaped Gland that is located in the
anterior neck on trachea
Thyroid Gland
What are the two (2) hormone produced by the thyroid gland
Thyroid hormone
Calcitonin
glands are ductless glands and directly release hormones into bloodstream
Endocrine glands
gland which is connected to a duct and do not not produce hormones
Exocrine
They are cells that produce thyroglobulin
Follicle cells
Cells that produce calcitonin
Parafollicular
They are the two thyroid hormones
Triiodothyronine (T3)
Tetraiodothyronine (T4)
Hormone that is released in thyroid when
calcium is elevated in the blood.
Calcitonin
Calcitonin inhibits the activity of
osteoclasts.
Iodide is transported into the thyroid gland by the primary transporter which is?
sodium/iodide symporter
The secondary I– transport enzyme that controls the
flow of iodide across the membrane.
Pendrin
It oxidizes Iodide to iodine
thyroidal peroxidase
Most thyroid hormone is transported by
THYROXINE-BINDING GLOBULIN (TBG)
it is the primary pathway (80%) for the peripheral
metabolism of thyroxine.
DEIODINATION
A condition in which there is an inability of the thyroid gland to supply sufficient thyroid hormone.
Hypothyroidism
Drug that induces hypothyroidism
Amiodarone
Type of hypothyroidism due to gland destruction or
dysfunction
Primary Hypothyroidism
Term for failure of the gland to develop
cretinism
Hypothyroidism due to a pituitary disorder inhibits TSH
Secondary Hypothyroidism
Type of Hypothyroidism where the hypothalamus lacks the ability to secrete TRH
Tertiary Hypothyroidism
also known as congenital hypothyroidism, and what is the diagnosis of this?
CRETINISM
Newborn screening
It is the end state of untreated hypothyroidism.
Myxedema coma
It is the main cause of goiters
Iodine deficiency
Type of Goiter that results from inadequate intake of dietary iodine.
Endemic goiter (Colloid goiter)