Thyroid Drugs

Question 1

Drug indicated for hypothyroidism

Answer 1

levothyroxine

Question 2

drug indicated for graves disease and hyperthyroidism

Answer 2

imidazole

Question 3

hypothyroidism comes with weight loss. Name the other adverse effects included here.

Answer 3

weight loss
headache
increase in appetite
sweating
heat sensitive

Question 4

imidazole sounds like iodine. Explain this link

Answer 4

It is the MOA. Decrease in concentration of iodine which reduces thyroxine formation

Question 5

B blockers block a huge storm. What is it?

Answer 5

thyrotoxicosis

thyroid storm

Question 6

Another drug for thyrotoxicosis?

Answer 6

radioactive iodine which binds to free T4 and inhibits the action

Question 7

what is thyrotoxicosis?

Answer 7

high levels of thyroid hormones

Question 8

causes of thyrotoxicosis (5)

Answer 8

grave's disease
goitre
drugs - amiodarone., thyroid replacement hormone
toxic adenoma
de quervains thyroiditis

Question 9

signs and symptoms of thyrotoxicosis

Answer 9

signs
- tremor, sweaty, tachy, myopathy, dyspnea
symptoms
- heat in tolerance, sweating, fatighure, palpitations, weight loss, increase in appetite

Question 10

tsh supressed, free t4 but normal t3

Answer 10

euthyroid sick syndrome, non-thyroidal illness

Question 11

which drug increases with the use of carbamezapine?

Answer 11

levo-thyroxine

Question 12

what 4 things have an effect on levo-thyroxine?

Answer 12

calcium, iron, PPIs, estrogen, antacids

Question 13

what is the name of the drug that treats hyperthyroidism?

Answer 13

neomarcazole

Question 14

name 2 other drugs that treat thyrotoxicosis

Answer 14

b blockers, radioactive iodine