Thyroid Hormones

Question 1

TH3

Answer 1

Hormone that is primarily responsible for the effects of TH. Most T4 is converted to T3 in peripheral tissues. TH receptors have an affinity for T3 5 times higher than to T4

Question 2

MCT and OATP

Answer 2

Protein families that transport T4 and T3 into cells. Damaged MCT8 leads to damaged neurological function.

Question 3

TH Receptor (TR)

Answer 3

Stimulates or inhibits transcription when it is bound to ligand. In the absence of a ligand, TR is not inactive but does the opposite of what it would in the presence of ligand.