Thyroid radio Flashcards

1
Q

Technetium-99m has an uptake mechanism similar to _______

A

Iodine

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2
Q

What type of image do we get in scintigraphy ?

A

2D

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3
Q

What are the techniques used in thyroid ?

A

US

Scintigraphy

CT/MRI - useful only in some px

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4
Q

what do we assess with US on thyroid ?

A

Evaluation of the :

** number of lesions

** Sites

** Calcifications

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5
Q

vascular evaluation of thyroid can be done with ?

A

color doppler

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6
Q

What radioisotope is indicated for diagnosis of Grave’s disease ?

A

Tc 99m-Pertechnetate

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7
Q

plummers diseases appears as

A

solitary hot nodule

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8
Q

what is the distribution seen with Tc 99m pertechnetate with graves disease ?

A

Homogenous distribution

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9
Q

what is the distribution seen with Tc 99m pertechnetate with multinodular goiter disease ?

A

Inhomogeneous distribution

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10
Q

what is the distribution seen with Tc 99m pertechnetate with subacute thyroiditis ?

A

Markedly reduced uptake

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11
Q

what tracer is used for scintigraphy ?

A

Iodine 131- gamma emitter, has diagnostic use

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12
Q

I-131​ is selectively taken up by what cells ?

A

Thyroid follicular cells with the help of sodium-iodine symporters

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13
Q

what type of emitter is Iodine-131 ?

A

both Beta and Gamma

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14
Q

what is the main thing we check for with scintigraphy of the thyroid ?

A

How the nodules appear.

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15
Q

What is the first line indication test for most patients with UNCERTAIN etiology of Thyrotoxicosis ?

A

Thyroid Scintigraphy

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16
Q

why Iodine-131 is preferred for therapy ?

A

Longer half-life

17
Q

What Radiotherapy used for benign and malignant thyroid disease ?

A

Iodine 131

18
Q

What is the use of Doppler in thyroid nodule imaging ?

A

For vascularization (combined with US)

19
Q

what does increased vascularization means on doppler when checking thyroid nodule ?

A

Usually indicate malignancy

20
Q

1st level instrument for thyroid diagnosis ?

21
Q

what is the 2nd level study for the thyroid ?

A

Scintigraphy

22
Q

what is the procedure we perform in case we want to study one of the nodules we find ?

A

Fine needle aspiration, but it is not diagnostic for Pappilary K.

23
Q

what is the frequency of the thyroid US ?

A

linear high frequency 7.5 Mhz

24
Q

how will appear benign nodular lesion on color Doppler ?

A

Hyper-echogenic signal

Regular nodule margin

25
how will appear Malignant nodular thyroid lesion on color Doppler ?
Hypo-echogenic signal Faded margins
26
what other radionuclides can we use for Thyroid except Tc-99 ?
Tetro-fosmin Sestamibi
27
what does thyroid scintigraphy allows us to highlight ?
1. hyper/hypo functioning of the nodule 2. Ectopic thyroid tissue 3. Metastasis
28
hot nodule on thyroid scintigraphy is probably
benign
29
Cold nodule on scintigraphy is probably
Neoplasia
30
what are the most common places of metastasis for thyroid cancer ?
Pelvis and chest
31
In what cases do we use PET-CT for thyroid K ?
When it's poorly differentiated and with high levels of Thyroglobulin
32
except FDG, what else can we use for PET in thyroid ?
Iodine-124
33
Papillary thyroid carcinoma metastasizes by ;
Lymphatic route
34
Follicular thyroid cancer metastasizes to ;
Blood, lung, and bone.