Ticket and Viro

Question 1

Which of the following bacteria is named after an investigator of typhus who was a victim of this disease?
a. Rickettsia akari
b. Ehrlichia erwingii
c. Rickettsia prowazekii
d. Ehrlichia chaffeensis

Answer 1

C

Question 2

Which of the following antimicrobials should not be used in treating RMSF? a. Doxycycline
b. Fluoroquinolones
c. Trimethoprim-sulfamethoxazole
d. Chloramphenicol

Answer 2

C

Question 3

Which of the following is also known to be an extrahuman reservoir of endemic typhus causative agent in the US?
a. Flying squirrel louse
b. Mites
c. Rat flies
d. Soft ticks
e. Hard ticks

Answer 3

A

Question 4

Identify the presumptive disease based in the Weil-Felix reaction. [OX-19 positive; OX-2 negative; OXK negative]
a. Epidemic typhus
b. Scrub typhus
c. Q fever
d. RMSF
e. Endemic typhus

Answer 4

E

Question 5

Which of the following is considered as reservoir host of rickettsialpox causative agent?
a. Wild rodents
b. Hard ticks
c. Humans
d. Dogs
e. None of the choices
6. All of the following infection

Answer 5

A

Question 6

All of the following infections manifest the presence of eschar, EXCEPT
a. Flea-borne spotted fever
b. Boutonneuse fever
c. Rickettsialpox
d. Endemic typhus

Answer 6

D

Question 7

7. Scrub typhus develops suddenly after 10-day incubation period with severe headache, fever and body pain. Which of the following vector can caused the above-mentioned disease?
   a. Rat fleas
   b. Chiggers
   c. Hard ticks
   d. Soft ticks
   e. Human louse

Answer 7

B

Question 8

Which of the following infections exhibits a small ulcer with a black crust at the site of a tick bite?
a. Rickettsialpox
b. Murine typhus
c. Rocky mountain spotted fever
d. Brill-Zinsser disease
e. Mediterranean spotted fever

Answer 8

E

Question 9

Q fever is characterized by both acute and chronic infections. Endocarditis is the most common form of chronic infections which is associated with which antigenic phase of the organism?
a. Phase 1
b. Phase 2
c. Phase 3
d. Phase 4

Answer 9

A

Question 10

Why is it necessary to process suspected specimens with C burnetii at BSL-3?
a. It can cause severe pneumoniae
b. The treatment is difficult due to because it is dependent on the phase of infection
c. It is acquired via inhalation
d. All of the choices

Answer 10

C

Question 11

11. All of the following statements are true about C. burnetii, EXCEPT
    a. The organism multiplies within vacuoles
    b. Doxycycline is the drug of choice for acute infections
    c. It is transmitted primarily by arthropod-bites
    d. It is the causative agent of Q fever
    e. Small obligate organisms similar to GN bacteria

Answer 11

C

Question 12

mountaineer from Costa Rica took a hike through a forested and brushy area near his home. The next morning, he noticed and removed a large insect from his thigh. About 7 days later, he experienced an abrupt onset of fever and malaise. He now seeks medical attention because he is concerned about a possible infection transmitted by the tick. Which of the following is known to be vector of the disease process?
a. Rat flea
b. Wood tick
c. Human body louse
d. Lone star tick
e. Chigger
13. All of the follo

Answer 12

B

Question 13

Which of the following histopathological cell is common in patients with RMSF?
a. Bacteria located intracellularly
b. Intracellular vacuoles
c. Morulae within neutrophils
d. Perivascular lymphocytes
e. Morulae within monocytes

Answer 13

A

Question 14

All of the following are TRUE about the Ricketssia, EXCEPT
i. Fastidious and obligate extracellular bacteria
ii. Cannot be culture using cell free media
iii. Multiply via transverse fission
iv. Humans are only accidental host except R. prowazekii
a. III and IV
b. I and III
c. II and IV
d. IandII

Answer 14

B

Question 15

Ehrlichiae and chlamydiae resembles each other, however they differ in
a. Cell wall synthesis
b. ATP synthesis
c. Nuclei acid synthesis
d. Protein synthesis

Answer 15

B

Question 16

17. All of the following statements regarding R. akari are correct EXCEPT
    i. It causes rickettsialpox
    ii. Ticks of the genus Amblyomma are responsible for transmission
    iii. The disease is mild
    iv. Disease is more common in urban than in rural areas
    a. I
    b. II
    c. III
    d. IV
    e. None of the choices

Answer 16

B

Question 17

Observing typical morulae in granulocytic leukocytes confirm that the patient is infected with
a. E. chaffeensis
b. C. burnetii
c. R. rickettsia
d. A. phagocytophilum

Answer 17

A

Question 18

Since C. burnetii can be transmitted by milk when animals like cows and goats are infected, what is the best sterilization method to destroy viable organisms?
a. Autoclaving
b. Filtration
c. Boiling
d. Radiation
e. High temperature, short time Pasteurization

Answer 18

E

Question 19

20. Identify the presumptive organism based on the Weil-Felix reaction. [OX-19-negative; OX-2- negative; OXK-positive]
    a. R. prowazekii
    b. O. tsutsugamushi
    c. R. akari
    d. R. rickettsia
    e. C. burnetii

Answer 19

B

Question 20

Ricketssial organisms are recovered in blood. What is the ideal time of collection for testing?
a. Decline period
b. Incubation period
c. Period of illness
d. Prodromal period
e. Convalescent period

Answer 20

E

Question 21

This disease is a recrudescence of an old typhus infection
a. Q fever
b. Trench fever
c. Rickettsialpox
d. Brill-Zinsser disease

Answer 21

D

Question 22

Which of the following infectious disease is often mistaken as rickettssialpox?
a. Anthrax
b. Syphilis
c. Rocky mountain spotted fever
d. Herpes
e. Measles

Answer 22

D

Question 23

Which of the following is the principal vector of endemic infection?
a. Xenopsylla cheopsis
b. Dermacentor andersonii
c. Leptotombidum delicense
d. Pediculus humanus corpons

Answer 23

A

Question 24

All of the following laboratory tests can be employed in diagnosing HME and HGE, EXCEPT
a. Platelet
b. CBC with WBC differential count
c. Urinalysis
d. SGPT/ ALT
e. None of the choices

Answer 24

C

Question 25

26. Which of the following diagnostic tests is most widely used in diagnosing rickettsial infections? a. Weil Felix test b. Complement fixation c. Polymerase Chain Reaction d. Cell culture using cell lines e. Indirect immunofluorescence and enzyme immunoassay

Answer 25

E

Question 26

diseased characterized by malaise, headache, rigors and fever developed in members of several families living in an unheated war-damaged house in an Eastern European country. Erythematous 2-6 mm macular red rashes appeared on the people’s trunks and later their extremities. Some of the people had coughs. The presumptive diagnosis is epidemic typhus. What is the hallmark of infection of rickettsial infections? a. Low grade fever b. Contact dermatitis c. Vasculitis d. Headache and body malaise e. All of the choices

Answer 26

D

Question 27

Which of the following statements is not true about R. prowazekii life cycle? a. Scratching the area of the bite allows the rickettsia excreted in the feces to penetrate the skin b. Rickettsiae are transmitted from one generation of lice to another c. The louse obtains the organism by biting infected human beings and transmits the agent by fecal excretion on the surface of the skin of another person d. Whenever a louse bites, it defecates at the same time

Answer 27

B

Question 28

Which specific structure is responsible for the ability of Rickettsia to adhere endothelial cells? a. Glycocalyx b. Outermembrane protein A c. Lipopolysaccharides d. Pili and fimbrae

Answer 28

B

Question 29

Which of the following antimicrobial is known to be the treatment of choice for Ehrlichiae? a. Doxycycline b. Fluoroquinolones c. Trimethoprim-sulfamethoxazole d. Chloramphenicol e. Penicillin G

Answer 29

A