Meyer-Overton Rule
the potency of anestheic gases is correlated to their solubility in olive oil
more than 90% of allergic reactions evoked by drugs administered occur within ____ minutes of administration
3
the only manifestation of an intraoperative allergic reaction may be __________
refractory hypotension
conditions associated with deficits in blood volume and extracellular fluid volume
trauma, pancreatitis, burns, bowel obstruction, sepsis, chronic HTN, diuretics, prolonged GI losses
clinical indicators of the adequacy of intraoperative blood volume replacement
HR, BP, CVP, Urinary Output, Arterial oxygenation and pH
consequences of massive blood transfusions
hypothermia, volume overload, dilutional coagulopathy, metabolic acidosis, hyperkalemia, citrate intoxication
AHTR signs and symptoms
acute renal failure, disseminated intravascular coagulation (DIC), —hypotension, hemoglobinurea and diffuse bleeding
