Tissues 11: Signalling between cell I Flashcards Preview

Tissues > Tissues 11: Signalling between cell I > Flashcards

Flashcards in Tissues 11: Signalling between cell I Deck (19)
Loading flashcards...
1

Why do cells communicate

1.Process information
(Sensory stimuli e.g. sight sound)

2.Self preservation
(Identify danger & take action e.g.spinal reflexes and sympathetic nervous system)

3.Voluntary movement
Getting from A to B
Completing tasks

4.Homeostasis
Thermoregulation
Glucose homeostasis

2

What is hypoglycaemia

Having too little glucose in the blood

3

What is the physiological response to hypoglycaemia

Glycogen is broken down
Gluconeogenesis occurs in the liver

4

Which cells are involved in glucose homeostasis

Alpha cells in islets of Langerhans in pancreas

5

What is the process in which Glucagon is secreted

a

6

What is endocrine signalling

Hormone travels within blood to act on distance organ/tissue/cells in the body

7

Give some examples of endocrine signalling in the body

Insulin produced in the liver acts on liver, muscle and adipose tissue
Adrenaline produced in the adrenal glands acting on the trachea and heart

8

What is hyperglycaemia

a

9

What is the physiological response to hypoglycaemia

Glucose uptake
Reduced glycogenolysis
a

10

What is the process of insulin secretion and effect

a

11

What is paracrine signalling

Hormone acts on an adjacent cell

12

Give some examples of paracrine signalling

Nitric oxide produced by endothelial cells in blood vessels
Osteoclast activating factors produced by adjacent osteoblasts

13

Give examples of signalling between membrane attached proteins

Blood borne virus(Hepatits C) detected in bloodstream by APC
APC digests pathogen and
a

14

Plasma membrane proteins on adjacent cells interacting is what form of communication

Membrane-attached proteins

15

Give some examples of membrane attached protein communication

HIV GP120 glycoprotein and
a

16

What happens when a T cell is activated and how is it activated

A cascade of reactions within the cell occurs
TCR is activated
T cell expresses Il-2
a
This is an example of autocrine signalling

17

What is autocrine signalling

Signalling acting on the same cell

18

Give some examples of autocrine signalling

a

19

What is the process of neurotransmission across the synapse

a