TIVA Opioids

Question 1

MOA, effects:

Answer 1

Act on mule, kappa and gamma receptors as agonsits

-> constipation, repiratory depression, analgesia, sedation, bradycardai, increase in PaCO2, histamine release with bronchospasm, hypotension
- decreases cerebral blood flow, cerebral blood volume, cerebral O2 consumption, and intracranial pressure

Question 2

Uses:

Answer 2

Diarrhea, analgesia, sedation, cough

Question 3

Side effects:

Answer 3

Urinary retention, decreased peristalsis, respiratory dderpression, cardiac depression, N/V

Question 4

Examples with doses:

Answer 4

Morphine - 10-15mg
Pethidine - 100mg
tramadol - 100mg
Fentanyl - 100 micrograms

Question 5

Side effects of NSAIDs

Answer 5

Gastric and duodenal ulcer (w/ rish of GI bleeding),
Increased risk of heart attack and stroke
Renal function impairment, aplastic anemia